- Jade Alleyne - Ruby Bisme-Lyons
- Maxim Baldry - Viktor Goraya
- Jodie Prenger - Debbie Green
- Noel Sullivan - Tony Watts
- Ian Hislop - Himself
- Paul Merton - Himself
- Alexander Armstrong - Himself
- David Crellin - Stan Thomas
- Krissi Bohn - Lucie Denham
- Dermot O'Leary - Himself
- Sue Devaney - Barbara Hopkins
- Lee Latchford-Evans - Himself
- Bhavik C. Pankhania - Alam Mohamed
- Steve Money - Arthur
- Shannon Hayes - Lizzie Mbeko
- Simon Naylor - Policeman
- Aqib Khan - Vijay Babu
- Julie Peasgood - Herself
- Charlotte Asprey - Madeleine Barry
- Andrew Readman - Trevor Lyle
- Nila Aalia - Question Time Host
- Kath Hughes - Woman in Blue
- Shaun McGowan - Archie Goolding
- Heather Dutton - Lesley
- Jack Kane - Clyde
- Natasha Jayetileke - Channel India Interviewer
- Roger Ringrose - Emergency Newscaster
- Eamonn Riley - Returning Officer
- Beatrice Curnew - British Expert
- Glen Fox - Office Expert
- Charles Armstrong - Economics Editor
- Kate Cook - Finance Expert
- Siri Ellis - Alliance Staff Member
- Andrew Byron - Ukrainian Police
- Nadia Albina - Holly Hill
- Gracy Goldman - Wytel Expert
- Peter McPherson - Stooge
- Tim Bruce - Politics Expert
- Jennifer Leong - Claverton Nurse
- Tamar Baruch - Alodie
- Elie Haddad - Tadeo
- Idriss Kargbo - Nigerian Lad
- Adele Oni - Nigerian Woman
- Dino Fetscher - Ralph Cousins
- Andrew Joshi - Point 5 Newsreader
- Elly Condron - Reporter
- Lee Comley - Network 85 Newsreader
- Michael Moreland - Martin Morris
- Adrianna Bertola - Teenage Girl
- Lynn Roden - Hester Finch
- Dan Starkey - Mr. Briscoe
- Adam Karim - Nurse
- Emma Fielding - Jane Bordolino
- George Bukhari - Jonjo Aleef
- Adam Little - Lee Lyons
- Kieran O'Brien - Woody
- Temi Wilkey - Lulu
- Zita Sattar - Yvonne Bukhari
- Mary Nightingale - Herself
- Rish Shah - Ahmed
- Jake Benson - Guard
- Stuart Wolfenden - Cliff's Dad
- John McGrellis - Head of Security
- Ross Grant - Billy Fitz
- Ellie Haddington - Dr. Moss
- Glen McCready - Voice of Signor (voice)
- Julia Sandiford - Media 24 Newsreader
- Fiona Pegram
- Kate Powis
- Charlotte Dean
- Ed Turner
- Andy Pryor
- Lucy Richer
- Karen Lewis
- Nicola Shindler
- Murray Gold
- Paddy McGuirk
- Jamie Roden
- James Russell
- Helen Dickson
- Jim Mulhearn
Kieran O'Brien hace el papel de Woody.
Alexander Armstrong interpreta a Himself en la serie.
Emma Thompson hace el papel de Vivienne Rook.
Anne Reid hace el papel de Muriel Deacon.
Rory Kinnear hace el papel de Stephen Lyons.
Jessica Hynes interpreta a Edith Lyons en la serie.
Russell Tovey interpreta a Daniel Lyons en la serie.
Ruth Madeley interpreta a Rosie Lyons en la serie.
T'Nia Miller interpreta a Celeste Bisme-Lyons en la serie.
Lydia West interpreta a Bethany Bisme-Lyons en la serie.
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