- Mike Grady - Michael Morva
- Cathryn Harrison - Jane Hardy
- Dominic Guard - Mick Brandon
- Rebecca Wheatley - Kelly Martino
- Zara Turner - Annabel Naylor
- Frances Cuka - Angie Kane
- Pam Ferris - Pat Trethowan
- Susan Fleetwood - Lady Cynthia Bottrell
- Susan Penhaligon - Mariah Penrose
- Tenniel Evans - Rev. Charles Stafford
- Jeff Rawle - Rev. Jordan
- Leslie Schofield - Anthony Treen
- Charlotte Coleman - Laura Kessell
- Eric Deacon - Neil Innes
- Emily Joyce - Morna Petheric
- David Bradley - Joe Mawnan
- Eleanor Bron - Edwina Coryn
- Nick Dunning - Jack Carlyon
- Frances White - Marian Pearce
- Anne Stallybrass - Mrs. Tremaine
- John McArdle - Alex Keir
- David Haig - David Miller
- John D. Collins - Armstrong
- Julia Deakin - Stephanie Vinter
- Kenneth Colley - Sam Peploe
- Oliver Ford Davies - Dr. Donald Treloar
- Tamsin Greig - Dr. Hinkley
- Bill Nighy - David Cleeve
- Rosalie Crutchley - Agnes Currow
- Jo Stafford - Sheena Penrose
- John Abineri - DCI Turner
- Anthony Green - John Leigh
- Jack Ellis - Miles Trednor
- Paul Bettany - Ian Greaves
- David Ross - Wainwright
- John McEnery - Ephraim Gardner
- Tristan Sturrock - Paul Mawnan
- Diana Hoddinott - Anne Pender
- Richenda Carey - Jane Rule
- Neil Newbon - Rob Tyzack
- Jim Norton - Owens
- David Bamber - Guy Bottrell
- Malcolm Storry - Bill Hewton
- John Hallam - Lionel Penmore
- Con O'Neill - Ben Walker
- Gwen Taylor - Alma Petheric
- Ronald Hines - George Aston
- Robert Vahey - Tony Goodden
- John Axon - Prison Kitchen Officer
- David Neal - Donald Thorne
- Rosalind Knight - Mrs. Prentice
- Nicholas Gecks - Prof. Faber
- Jeremy Clyde - Lord Hugh Bottrell
- Hilary Mason - Edith Riddle
- Leonie Mellinger - Polly Innes
- David Ellison - Jack Choak
- Tilly Vosburgh - Mrs. Sowden
- Jan Pearson - Mary Clark
- Nigel Terry - Lawrence Vinter
- Dominic Mafham - Owen Mathers
- Charles De'Ath - Stephen Ling
- Ian Bartholomew - Mick Sennan
- Roger Sloman - Gerald Prout
- Michael Fenton Stevens - Marcus Howell
- James Faulkner - Steven Lander
- David Schofield - Joe Penrose
- Martha Cope - Sarah Penna
- Catherine McCormack - Asenath Gardner
- Brigit Forsyth - Ella Jones
- Mary Wimbush - Mrs. Christopher
- John Bowler - Dan Hobden
- Emily Hamilton - Jean Lander
- Kenneth Watson - Carter
- Louise Jameson - Tilly Rawle
- Kate Steavenson-Payne - Josie Perrett
- Susan Wooldridge - Patricia Cleeve
- Mark Chapman - PC Jones (uncredited)
- Barbara Kirby - Registrar
- Rupam Maxwell - Paul Redman
- Pandora Colin - Milli
- Georgine Anderson - Barbara Prout
- Richard Cubison - Armed Police Officer
- David Sterne - Pub Landlord
- Dee Sadler - WPC Angela
- Christopher Ashley - Sgt. Luff
- Laura Brattan - WPC Eva Luff
- Carole Nimmons - Sarah Riddle
- Geoffrey Larder - John Gander
- Alan Stocks - Matthew Riddle
- John Cassady - Landlord
- Peter Stockbridge - Mr. Penrose
- Stephanie Buttle - Hilda Clemo
- Joanne Thirsk - Alice Harvey
- Robert Demeger - James Clemo
- Giles Taylor - Clifford Rule
- Gabrielle Hamilton - Lily Armitage
- Dinah Stabb - Celia Jordan
- Ellie Haddington - Katherine Geach
- Paul Moriarty - Abe Geach
- Mark Letheren - Giles Vinter
- Geoffrey Leesley - Glynn
- Brendan O'Hea - David Jones
- Roy Alon - Harry Tremaine
- Barry Jackson - Alexander Greaves
- Tony Guilfoyle - Bill Clark
- Kevin Molloy - George Garner
- Emmet Bergin - Alan Forbes
- David Westhead - Freddie Tremaine
- Roger Heathcott - Custody Sergeant
- John Bleasdale - Warder
- Robin Browne - ACC Waters
- Geoffrey Bayldon - Judge
- Geoffrey Bayldon - Gilbert Rawle
- Sean Chapman - Bonetti
- Andrew Hilton - Prison Governor
- James Lailey - Soco
- Andrew Greenough - PC
- Andrew Readman - George Warne
- Will Ashcroft - Mr. Dart
- Margo Gunn - Alison Keir
- Adam Kotz - Dave Penryn
- Brenda Cavendish - Mrs. Tregelles
- Brian Gwaspari - Major Tregelles
- Diana Payan - Mrs. Morgan
- Doyne Byrd - Devenish
- Harriet Ashcroft - Ruth
- Tom Eastwood - Barman
- Mark McKenna - Drake
- Maureen Bennett - Georgie Howell
- Jack Hulland - Man in Pub
- Kieron Forsyth - Gary Penhale
- Brian Poyser - Brian Evans
- Martin Hancock - Dave
- Bruce Barnden - Harry
- Richard Dempsey - James Coryn
- Ralph Riach - Dr. Bonner
- Simon Paisley Day - SOCO
- Selina Griffiths - Administrator
- Philippa Howard - Girl in chip shop
- Lennox Greaves - Patrick Rowland
- René Zagger - Rob Mills
- Julia Chambers - Anne Dutton
- Ian Redford - Alan Dutton
- Ken Drury - Div. Com. Thomas
- Jonathan Docker-Drysdale - Dr. Gale
- Cheryl Hall - Mrs. Ling
- Martyn Whitby - Inspector Phillips
- Albie Woodington - Alan Whear
- Lesley Clare O'Neill - Liz Penrose
- Barrie Houghton - John Flemming
- Desmond McNamara - Bill Marrack
- Dido Miles - Professor Tynk
- Jo Anderson - Mrs. Choak
- Sally Edwards - Elizabeth Rawle
- Christian Rodska - Giles Rawle
- John Woodnutt - Dr. Angwin
- Jo-Anne Stockham - Anne Carter
- Naomi Wirthner - Doctor
- Rebecca Raybone - Nurse Avril
- Matthew Scurfield - DS Rinnick
- James Curran - Surgeon
- James Curran - Chief Constable
- Arthur Whybrow - Zeb Pendower
- Grant Masters - Jake Marberry
- Andy Robb - Corliston
- Linda Broughton - Mrs. Nankervis
- Antonio Elliott - Eduardo
- Stuart Organ - Eddie Sowden
- Grace Mitchell - Irene Wycliffe
- Chris Barnes - Brian Buddle
- Anna Skye - Georgie Carlyon
- David Savile - Garforth
- Brian Miller - Harry Venning
- David J. Nicholls - Scrap Metal Merchant
- David J. Nicholls - Ray Gurney
- Neil McCaul - Tom Rees
- Bernard Latham - Edward Tregeddick
- Buffy Davis - Cathy Cotterill
- Robert Perkins - Davie Trelan
- Chris MacDonnell - Insp. Murrish
- Dione Inman - Sally Hobden
- Christopher Driscoll - Caravan Park Owner
- Christopher Driscoll - Inspector Perry
- Elaine Hallam - Fiona Treloar
- Mark Womack - Keith Megson
- Allan Surtees - Don Collins
- Dominic Knutton - Dave
- Toby Ross-Bryant - Owen
- Glyn Grain - Mike Trigg
- Marjorie Yates - Martha Collins
- Shaun Curry - Sgt. Brennan
- Michael Goldie - Fisherman
- John Shrapnel - Dr. Sam Malvern
- Jacqueline Phillips - Janice (SOCO)
- Alan Penn - Burrows
- Martin Ball - Harper
- Jon Croft - Ted
- Jenifer Armitage - Patricia Naylor
- Hans Matheson - Gary Creed
- Eileen Davies - Hannah Creed
- Maryann Turner - Old Woman
- Michael Cronin - Hugh Samford
- Robert Putt - Lionel Samford
- James Vaughan - Paul Gillespie
- Nigel Humphreys - ACC Ken Lyman
- Colin Edwynn - Barman
- Raymond Mason - Len Rawlinson
- Sidney Livingstone - Harry Burrows
- Josephine Butler - Karen Drew
- Pat Rossiter - Rose Burrows
- Clive Kneller - Wisson
- Geoffrey Church - Donald Mason
- Frankie Jordan - Mrs. Rand
- Alan Williams - Mr. Rand
- Sally Armstrong - Joanne Shaw
- Michael Cochrane - Mr. Price
- Katy Cavanagh - Mrs. Vassie
- Jamie Lee - Local PC
- Virginia Fiol - SOCO
- Amanda Abbington - Local WPC
- Tom Mannion - DS Oren
- Alan Bodenham - Westney
- Mark Jefferis - Colin the Landlord
- Marian McLoughlin - Fiona Jay
- Marian McLoughlin - Lynne Carney
- Steve Whyment - Tregeen
- Elizabeth Rider - Trisha Tyzack
- Bruce Byron - Blackie Tremain
- Sally Watts - WPC Hendricks
- Brigid Zengeni - Janet
- Judy Norman - Shirley Trednor
- Peter McNamara - Donald Ferris
- Paul Panting - Baldry
- Mary Woodvine - Margaret Ezzard
- Alan Cody - Ted Fisher
- Edward Clayton - Sgt. Cannon
- Linda Slade - Vanessa
- Jason Salkey - Alvin
- Vincent Brimble - Ken Davis
- Ian Brimble - Pete Davis
- Patrick Romer - Foreman
- Richard Willis - Rick Brown
- Miranda Bell - Mrs. Goodwin
- Emily Richard - Paula Tresize
- Mark Kempner - Auctioneer
- Raymond Adamson - Auction Porter
- Sharon Duce - Supt. Le Page
- Peter Gale - John Curran
- Bohdan Poraj - Richard Petheric
- Nigel Anthony - Vernon Randall
- Sarah Thurstan - Christine Stevens
- Pete Lee-Wilson - Kevin Kessell
- Richard Moore - Richard Penmore
- Adam Bareham - Inspector Carson
- James Larkin - Mike Penmore
- Diane Adderley - Pam Wright
- David Baukham - Jed Wright
- Chris Donnelly - Young PC
- Nick Brimble - Tom Durden
- Susan Tordoff - Helen's Sister
- Ian Kirkby - DS Naylor
- Jack Carr - William Perrett
- Darren Tighe - Gary Tregenna
- Mark Lewis - Sam Venning
- Felicity Dean - Lisa Venning
- Neil Maskell - Tully
- Alan Perrin - Noble
- Geoffrey Drew - Crimmens
- Frankie Cosgrave - Mrs. Patterson
- Martin Sadler - Crow
- Graham Bryan - Andy
- Josie Kidd - Ivy Tinnion
- Simon Markey - Forensic Lab Tec.
- Alan Rowe - Minister
- Adie Allen - Janet Miller
- Jeff Nuttall - David Miller
- James Taylor - Consultant
- Quentin Jones - Young Doctor
- Sally Faulkner - Sian
- Norman Gregory - Sergeant Hogg
- John Joyce - Andrew Hardie
- Martin Herdman - Billy Davidson
- Chas Bryer - Joe Charlton
- Michael Attwell - DCC Stevens
- John Abbott - Dan Farthing
- Virginia Clay - SOCO
- Annette Bentley - Sandra Oaksey
- Pauline Turner - Kim
- Calum MacPherson - Brendan Oliver
- John Vine - Raymond King
- John Flanagan - Lassiter
- Gerard Horan - DS Caplin
- Anthony Smee - Rupert
- Dean Harris - Tolman
- Paul Venables - Hugh Barrington
- Chris Jury - Toby Penwarren
- Arthur White - Taxi Driver
- Kate Byers - Laura Starkie
- Andy Mulligan - Cafe Stall Holder
- Bernard Gallagher - Vic Garland
- Mairead Carty - Wendy Chiverton
- Chris Humphreys - Jim Hornby
- Shelagh McLeod - Jane Trier
- Michael Nardone - Joe Duggan
- Clive Francis - Ch. Insp. Bonner
- Raymond Brody - Landlord
- Peter Harding - Tom Dacre
- Cristian Solimeno - DC Hall
- Cristian Solimeno - DC Dick Hall
- Sammy Johnson - Adrian Wright
- Andrew Bicknell - Alan Trier
- Flip Webster - Mrs. Wheeler
- Charlie Hayes - Ruth Wycliffe
- Kenneth Bryans - DC Harris
- Donald Pickering - Sir Martin Cook
- Belinda Sinclair - Patricia
- Tim Wylton - Franks
- John Castle - Selby
- Ann Beach - Mrs. Wimble
- Jan Graveson - Rosie
- Brian Croucher - Det. Supt. Healey
- Morgan Jones - Greg Fry
- Gregory Chisholm - David Wycliffe
- Albert Welling - Technician
- David Firth - Angus
- Annie Leatherby - Group Leader
- Natasha Sutherland - Young Mum
- John Glenister
- Jack Shepherd
- Alan Wareing
- Michael Owen Morris
- Steve Goldie
- Ferdinand Fairfax
- Rob Heyland
- Julian Jones
- Scott Cherry
- Isabelle Grey
- Carolyn Sally Jones
- Patrick Harkins
Jack Shepherd interpreta a Detective Superintendent Wycliffe en la serie.
Bill Nighy interpreta a David Cleeve en la serie.
Catherine McCormack interpreta a Asenath Gardner en la serie.
David Schofield interpreta a Joe Penrose en la serie.
John Shrapnel interpreta a Dr. Sam Malvern en la serie.
Clive Francis interpreta a Ch. Insp. Bonner en la serie.
Rosalind Knight interpreta a Mrs. Prentice en la serie.
Jimmy Yuill interpreta a DI Doug Kersey en la serie.
Helen Masters hace el papel de DI Lucy Lane.
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