- Summer Glau - Water Wu / Miss Jones
- Paul Lazenby - Bendix
- Gigi Jackman - Nurse
- Sarah Hayward - Waitress
- Rob Heschl - Customer (uncredited)
- Patricia Cullen - Doctor
- Dustin MacDougall - Dealer
- Carlo Yu - Chen
- Michael Denis - Tony Gelardi
- Leo Chiang - Lau
- Jeff Fahey - Jack
- Naiah Cummins - Uni Cop
- Meena Mann - Reporter
- Dimitry Tsoy - Yenling
- Colin Foo - Older Bald Chef
- Paul Chih-Ping Cheng - Dragon Head 2
- Simon Leung - Raymond Tang
- Derek Kwan - Triad Guard (uncredited)
- Julian Paul - Viktor
- Arpad Balogh - Serge
- Raresh DiMofte - Babinov
- Sara Canning - Alana
- David Stuart - Meeting Leader
- Justin Turnbull - Ray
- Billy Wickman - Leo
- Kevin Durand - James Baxter
- Markjan Winnick - Buddy
- Sean Campbell - Carl
- Gail Matthius - Waitress
- Lillian Doucet-Roche - Jill
- Mark Dacascos - Monk
- Mark Dacascos - Kun Zi
- Jesse Irving - Danny
- Cranston Johnson - Frank Fletcher
- Caitlin Stryker - Pam Fletcher
- Rhona Rees - Inspector Alice Riley
- Zak Santiago - Sgt. Joe Torres
- Jesse Hutch - Inspector Boyd
- Danny Wattley - Officer Johnson
- Noel Johansen - Officer Carlson
- Richard Keats - Lawyer
- Khamisa Wilsher - Natalie / Metal Wu
- Amanda Friesen - Barista
- Tommy Flanagan - Alec McCullough
- Serge Houde - The Duke
- Tzi Ma - Mr. Young
- Lewis Tan - Lu Xin Lee
- Celia Au - Ying Ying
- JuJu Chan - Zan Hui
- Travis Caldwell - Gideon
- Anthony Shim - Roland Ong
- Robin McLeavy - Maggie McCullough
- Peter Chao - Young Tommy
- Yalun Tu
- Jessica Chou
- John Wirth
- Iko Uwais
- Jay Daniel Beechinor
- Katheryn Winnick
- Michael Frislev
- Morris Chapdelaine
Iko Uwais interpreta a Kai Jin en la serie.
Katheryn Winnick interpreta a Christine Gavin en la serie.
Tommy Flanagan interpreta a Alec McCullough en la serie.
Byron Mann hace el papel de Uncle Six.
Li Jun Li interpreta a Jenny Wah en la serie.
Lawrence Kao hace el papel de Tommy Wah.
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