- Becky Ann Baker - Dr. Reeples
- Michelle Barker - Julie McCray
- Jim Burk - Cop #1
- Bostin Christopher - Medical Student
- Rony Clanton - Bernard
- Ana Cristina Oliveira - Aurora
- George DiCenzo - Therapist
- Brother Eden Douglas - Barking Man
- Linda Emond - A.D.A. Strictler
- Santo Fazio - Cort
- Meg Gibson - Forensics Nurse
- Michael Hyatt - CPEP Nurse
- Gloria Irizarry - Mrs. Lopinta
- Eddie Korbich - Ronald Pulitz
- Paul Lazar - Willie Watches
- Saundra McClain - Guest
- Method Man - Self
- Leland Orser - Wendall Rickle
- Kevin Pinassi - Mr. Hooper
- Stuart Rudin - Louie
- Jay O. Sanders - Ed Butowski
- Tyree Michael Simpson - Officer Lopez
- Irma St. Paule - Elizabeth
- Erik Per Sullivan - Tucker Banger
- Matthew Sussman - Emanuel Treyhill
- Christopher Tracy - Extrication Officer
- Ronald Yamamoto - Todd Gardner
- Lisa Panagos - Fantasy Girl (uncredited)
- Andre Royo - Psychiatric Patient (uncredited)
- Ernie Anastos - Self
- Tom Bloom - Barry Rickle
- John Elsen - Reporter
- Kristin Griffith - Carolina Rickle
- Jamie Harrold - Bipolar Patient
- Anibal O. Lleras - Actor
- Anthony Quarles - CO Cruz
- Robert Turano - Sgt. Wilkinson
- Anne Twomey - Judge Manheim
- Curt Hayward - Bipolar Transvestite (uncredited)
- Russell Hornsby - Hospital Receptionist (uncredited)
- Isiah Whitlock Jr. - Reviewer (uncredited)
- Ron Howard
- Brian Grazer
- Tony Krantz
- Peter Berg
Michelle Forbes interpreta a Lyla Garrity en la serie.
Billy Burke hace el papel de Dr. Abe Matthews.
Patricia Clarkson interpreta a Tammy Banger en la serie.
Capítulo disponible en las siguientes plataformas:
