- Alvina August - Trina
- Kurt Long - Phil
- Shannon Chan-Kent - Cindy
- Sam Richardson - Toast (voice)
- Tony Hale - Butter (voice)
- Nicole Byer - 40 oz Bottle (voice)
- Eddie Griffin - 40 oz Bottle (voice)
- Cedric the Entertainer - Trash Can (voice)
- Wes Studi - Spoon (voice)
- Elizabeth Bowen - Nancy
- Brandi Alexander - Simone
- Carl McDonald - Alice
- Nick Ouellette - Hipster Barber
- Michael Delleva - Clerk
- Ron Chartier - Appraiser
- Tyson Bellusci - Police Officer
- Stephanie Sy - Beautiful Woman
- Brittany Mitchell - Brittany
- Gabe Khouth - Burnt Toast Man
- Jack McBrayer - Sad Face (voice)
- Jacki Gunn - Receptionist Margaret
- Chris Cound - Boom Box Guy
- Herbert Duncanson - Security Guard
- Diana Pavlovská - Ms. Henschke
- Leanne Allen - Marigold
- Sarah Rodgers - Patience
- Lyle Reginald - Alex
- Adam Kirschner - Process Server
- Janet Glassford - Leasing Agent
- Casey Manderson - Adam
- Paul Snider - Make-Out Guy
- Lil Rel Howery - BPFR T-Shirt (voice)
- Nathan Lee Graham - Darque Noir
- Donna Benedicto - Marley
- Shannon Kook - Ziggy
- Cree Summer - Paper Bag (voice)
- Cassandra Constance Bolinski - Tech Girl
- Sam Rahmani - Zadi
- David Ury - Al Durian (aka Trench Coat)
- Keith David - Bible (voice)
- Justyna Bania - Surgical Mask Woman
- Jarrett Carlington - Rich Boy
- Lossen Chambers - Bus Driver
- Bryan Demore - Tech Bro
- Jasmin Dring - Asian Grandma
- Clare Filipow - Lorna the Mourner
- Krista Magnusson - Police Officer
- Phil Trasolini - Wild Hair Guy
- Link Baker - Officer Wyatt
- Peter Kelamis - Lt. Svoboda
- Susan Hanson - Mrs. Chang
- Miguel Pinzon - Tommy
- Megan Robinson - Abby
- Kimberly Maxwell - Britta
- Cara Mantella - Mary
- Chris Mayers - Matt
- Cherie Danielle - Aimee
- Pierce Lackey - Stern Cop
- Lauren Halperin - Lady with Sign
- John Crow - Activist
- Debra Nelson - Activist
- Cristian Gonzalez - Activist
- Aimee Garcia - Laura
- Marquita Goings - Hype
- Andy Cohen - Dave
- Emily Barnes - Julie
- Dayo Abanikanda - Kyrie
- Isiah Whitlock Jr. - Mr. Jackson
- Tiffany Denise Hobbs - Libby
- Regina Ting Chen - Dr. Julia Cho
- Paul Brian Johnson - Craig
- Sean Hankinson - Frank
- Helen LeRoy - Paula
- Thy Bui - Reporter
- Billy Magnussen - Denny 'Dee Dee' Davis
- Cindy L. Jefferson - Gloria
- Chase Anderson - Ronald
- Bethany Geaber - Dawn
- Raiany Silva - Vicky
- N'dia Lamar - Claudette Colvin
- Angela Davis - Harriet Tubman's Secret Girlfriend
- Donna Biscoe - Annie Malone
- Savannah Rose Scaffe - Motel Clerk
- Ian Hoch - Richard
- Cooper Elliott - Bald Guy
Capítulo disponible en las siguientes plataformas:
