- James McCaffrey - Michael Payton / Joe Astor
- James McCaffrey - Michael Payton / Joe Astor (archive footage)
- William Russ - Townsend
- Alan Scarfe - Flagler
- Parley Baer - Finch
- Stephen Macht - Alan Reece
- Frank John Hughes - Bobby Finn
- David Dean - Matt Conlon
- Bruce A. Young - Administrator
- Dale Wilson - John Talmadge
- Cam Clarke - Pulse (voice)
- Nancy Valen - Bianca Carson
- Mackenzie Gray - Fred Tyler
- Reggie Theus - Jeff Desmond
- Blu Mankuma - Mr. Kempler
- Michael Kopsa - Gil Yates
- Michael Fairman - Abe Goldberg
- Jay Brazeau - Dr. Norwood
- Garry Chalk - Quince Toland
- Jaason Simmons - Steve Hoffman
- Kari Matchett - Beatrice
- Tom Wright - Travis Parker
- Barbara Tyson - Stephanie Sloan
- John Newton - Billy Denver
- Colin Cunningham - Peter Markham
- Samantha Ferris - Reporter
- Jerry Wasserman - Philip Leech
- Sam Vincent - Jesse Pollard
- John Cothran - Vance
- Fay Hauser - Mara Wilkes
- Scott Vickaryous - Sebastian
- Ralph Manza - Anton Pollard
- Brandy Ledford - Tina Bloom
- Allison Hossack - Rachel Caine
- Camille Winbush - Lucy Wilkes
- Jason Carter - Alec Conner
- Philip Maurice Hayes - Rafe
- Sean Day Michael - John
- Angel Boris Reed - Gina Corrente
- Ben Derrick - Gene
- Nicole Prescott - Jessie Karns
- Terry Barclay - Don Corman
- Gavin Buhr - Casey
- Deanna Williams - Moderator
- Ted Kozma - Dorne
- Tim Thomerson - Hanson Dekker
- Tim Thomerson - Lyle Hinkle
- Anthony Harrison - Frank Madden
- John 'Bear' Curtis - Bob Derevere
- William S. Taylor - Josef Kwame
- Sami Chester - Nichols
- Lisa McCullough - Andi
- Mark Pellegrino - Yuri
- Josh Cruze - Madison
- Charlie Spradling - Anna
- Charlie Spradling - Dominique
- David Q. Combs - Lobby Guard
- Biff Manard - Guard
- Karen Maruyama - Police Operator
- Ric Roman Waugh - Car Jacker
- Sydney Walsh - Elizabeth Huston
- Lee Chamberlin - Delia Thorne
- Jon Polito - Councilman Strand
- Dawn-Lyen Gardner - Ronnie Wilkes
- Jackie Millines - Injured Officer
- Julia Parton - Reporter
- Brian J. Williams - Burglar
- Richard Burgi - Lane Cassidy
- Carmen Argenziano - Chief Pomeroy
- Quinn Duffy - Tim Rackham
- Paul Freeman - Dr. Samuels
- Julie Merrill - Rachel
- Joseph Carberry - Carl
- Adam Hendershott - T.J.
- Charles Noland - Rimmer
- Jack Shearer - Nate Benedict
- Don Stark - Manny
- Michael Champion - Erick Van Hook
- Annabelle Gurwitch - Nash
- Peter Keleghan - Arnie Nevelson
- Wendie Malick - Iris Nevelson
- François Chau - Bobby Murabito
- Tim DeZarn - Johnson
- Carol Huston - Sally Gerraro
- Brian Mallon - Morrison
- Wendy Robie - Nurse
- Tony Devon - Doug Faison
- Vincent Guastaferro - Lynheim
- Amy Steel - Lisa Hinkle
- Carl Gabriel Yorke - Reporter
- Richard Bradford - Preston Baxley
- Patricia Charbonneau - Ella Keats
- Bryan Cranston - Garrett Berlin
- David Parry - Travis
- Jeris Poindexter - Johnny
- Douglas Rowe - Howard
- Sam Behrens - Frederick Lang
- Joyce Hyser - Claire
- Susan Lentini - Bartender
- Vito D'Ambrosio - Milt Kisco
- John Mese - Matt Shepard
- Signy Coleman - Sylvia
- David Cowgill - Alan
- Scott Lincoln - Stathis
- Leslie Neale - Karen
- John Neville - Leonard Price
- Douglas Roberts - Dr. Daniels
- Andrew Airlie - Dr. Harmon
- Andrew Airlie - Charles Peterson
- Natanya Ross - Kimberly
- Rika Hofmann - Fatima
- Vladimir Skomarovsky - Moro Sarat
- Roger Cross - Carpenter
- Kim Kondrashoff - Security Guard
- Don Charles McGovern - Rowdy
- Joe Norman Shaw - Shelton
- Daryl Shuttleworth - Harding
- Fulvio Cecere - Bartender
- Rik Kiviaho - Masked Commando Leader
- Mike Genovese - Jason
- Mike Genovese - Harold Benning
- Brian Martell - Field Agent
- Glenn Morshower - Walter Powell
- Musetta Vander - Natalya Marakova
- Michael Watson - Ilya Nadgurin
- Jay Acovone - Victor Rand
- Sherman Augustus - Richard Gage
- Sean Campbell - Rick Daley
- Carlo Rota - Harry Ibarra
- Barbara Gates Wilson - Guard
- Jennifer Burry - Jessica St. James
- Frank Cassini - Lieutenant Romero
- Robert Kerbeck - Dr. Block
- Robert Kerbeck - Ben Sakmar
- Garvin Cross - Patrick
- Allan Havey - Jay Lowery
- Maria Canals-Barrera - Carla
- Korrine St. Onge - Tracey
- Skipp Sudduth - Terry Molloy
- Scott Swanson - Carl Liggett
- Luc Corbeil - George Hanscomb
- Alex Diakun - Harold Peterman
- John Heywood - Rent-A-Cop
- Eric Keenleyside - Frank Taylor
- Debra Kurtz - Jewelry Store Clerk in robbery
- Ingrid Torrance - Wallace
- Réal Andrews - Mark Keegan
- Dennis Corrie - Dr. Bishop
- Lochlyn Munro - Second Hitman
- Chandra West - Becky
- Ken Kramer - Alfred Noyes
- Charlotte Lewis - Evangeline Raines
- Byron Lucas - Zach
- Barry Pepper - Johnny Hodge
- Linden Banks - Uncle Rich
- Paul Cowling - Bartender
- Bill Croft - Hyatt Griffith
- Victoria Jackson - Samantha Taylor
- Keegan MacIntosh - Ben Taylor
- Sean Allen - Braxton
- Dean Wray - Lead Cyclist
- Dean Wray - Cyrus
- Anthony Santiago - Reyes
- Don S. Davis - Lloyd
- Janne Mortil - Evie
- Steven Roy - Mick Broussard
- Carrie Schiffler - Sheila Wagner
- Jim Shield - Cletus
- Doug Abrahams - Chief Harris
- Rob Daprocida - Mico
- James Dugan - Raymond
- Brian Gromoff - Drake
- Lalainia Lindbjerg - Clarice
- Camille Mitchell - Ruth
- Seth Peterson - Robbie
- Bud Klasky - Biker (uncredited)
- Don MacKay - Dr. Newhouse
- Tony Nardi - Assistant
- Jamie Rose - Gloria
- Jamie Rose - Marian Franklin
- Rebecca Staab - Valerie Reed
- Scott Olynek - Gang Member
- Chris Bradford - Justin Turner
- Julie Condra - Grace Mayfield
- Myles Ferguson - Kyle Reese
- Christian Goutsis - Jason
- April Telek - Amanda
- April Telek - Hostess
- Stephen Hair - Mr. Reese
- Heather Lea MacCallum - Mrs. Reese
- Tobias Mehler - Sanders
- Todd Sandomirsky - Fosnight
- Walker Brandt - Gwen Reardon
- Oscar Goncalves - Roland
- Debbie Podowski - Monica
- Bernard White - Darius
- Alexandra Bokyun Chun - Lai
- Steve Bacic - Dirk Minyard
- Steve Bacic - Parker
- Mitchell Kosterman - Milo
- Callum Keith Rennie - William T. Lennox
- Gerry Rousseau - Eli Reed
- Rod Wilson - Deekins
- Paul Dunphy - Anchorman
- Kirk Jarrett - Norris
- Ian Patrick Williams - Clarence
- Sean Millington - Reporter #1
- Kathleen Duborg - Reporter #2
- Paul Bittante - Thug - dog handler
- Joy Coghill - Mother Grace
- William deVry - Geoffrey Vollis
- Anne Farquhar - Karen
- Jennifer Gatti - Rachel Davenport / Elizabeth Gantry
- Sharisse Baker-Bernard - Andrea Grant
- Dwight McFee - Phil Tucker
- Tim O'Halloran - Edward T. Hutchinson
- Marty Rackham - Jerome Margosian
- Patrick Brown - Jessup
- Patricia Casey - Rose
- Heather Hanson - Luke's Girlfriend
- Cyril O'Reilly - Luke Riker
- Peter Strand Rumpel - Moke
- Jill Teed - Marshall Trent
- Joel Wirkkunen - Alvin Phelps
- Elan Ross Gibson - Pauline
- Jane Perry - Social Worker
- Raphael Sbarge - Timothy Ramsay
- Michael David Simms - Roger Maddox
- David Kaye - Mayor Tillman
- David Kaye - John Gibson
- Donna White - Neighbor
- Peter Wilds - Nick Marcellus
- Lisa Akey - Barbara Ann 'Bambi' Dexter
- Jeff Burnett - Paul Brickley
- Adrian G. Griffiths - Lambert
- John Pyper-Ferguson - Ray Bollo
- John Pyper-Ferguson - Harper
- William Katt - Arno Krafft
- Bill Macy - Jack Surber
- Bill Macy - Marty
- David Abbott - Chief Mott
- Gordon Currie - Noel Flynn
- Andre Danyliu - Captain
- Keegan Connor Tracy - Darlene Ross
- Keegan Connor Tracy - Charmayne Grimes
- Barry Greene - Kelsey
- Traci Lords - Talia Massey
- David Palffy - Jules Vandeveer
- David Palffy - Porter
- Donnelly Rhodes - John Lazenby
- Carrie-Anne Moss - Stacy Taylor
- Ian Tracey - Mickey Finch
- Alan van Sprang - Karl Warrick
- Julie Bond - Marge
- Mike Dopud - Emil
- Murray Lowry - Sammy Travers
- Jeffrey Max Nicholls - Luke
- Stephanie Niznik - Lena Weisinger
- Jed Rees - Benny
- Manoj Sood - Sintong Nameh
- Kirby Morrow - Tim Vernon
- Charles Payne - Cop
- Garwin Sanford - Michael Anthony Cornell / Alec Brody
- Mark Schooley - Jail Officer
- Kim Tyler - Nancy Cornell
- Zoltan Buday - Firefly
- Brian Jensen - Priest
- Lauren K. Robek - Georgia
- Jonathan Walker - John Morton
- Marek Wiedman - Taxi Driver
- Kate Robbins - Fast Food Manager
- Robert Parent - Skinhead
- Claudette Mink - Louise
- Mark Humphrey - Marshall
- Jay Hilliker - Drive Thru Kid
- Doug Chapman - Simpkins
- Lori Triolo - Gloria Rafferty
- Johnny Cuthbert - Ray Walker
- Stefan Arngrim - Theodore Barnsfield
- Priscilla Barnes - Sheila Dunn
- Robert Culp - Mark Bishop
- Bob Dawson - Colonel Taylor
- Martin Evans - Varik Lendl
- Suki Kaiser - Mrs. Drake
- Phillip Mitchell - John Hightower
- Rick Ravanello - Sergio 'Sonny' Celeste
- Rick Ravanello - Tremaine
- Michael Callan - Albert Corrente
- Nadia Capone - Loretta DeFalco
- Patrick Stevenson - Dave Morris
- Patrick Stevenson - Scott Kincaid
- Terence Kelly - Johnny
- Rob Lee - Sandy DeFalco
- Shawn Macdonald - Harvey Green
- Craig March - Rex
- Shae Marks - Connie Matuszak
- J. Douglas Stewart - Don Myers
- J. Douglas Stewart - Starr / Max
- Silvio Pollio - Kenny Matuszak
- Mark Acheson - Hooper
- Tosca Baggoo - Dr. Manville
- Brennan Elliott - Neil Royce
- Lance Gibson - Bouncer
- Tom McBeath - Harlan Royce
- Julie Patzwald - Samantha Franklin
- Robert Saunders - Police Officer #1
- Gerard Plunkett - Dieter Imhoff
- Gerard Plunkett - Jules Morak
- Nancy Sivak - Andrea Parker
- Michelle Skalnik - Terri Howell
- Pablo Coffey - Forest Ranger #1
- Geoff Adams - Forest Ranger #2
- John Henry Canavan - Ben
- Cory Dagg - Pete
- Michael Mahonen - Dirk Hanley
- Katie Mitchell - Iris Benson
- Teryl Rothery - Julie Stone
- John Tench - Al King
- John Tench - Harris
- Michelle Thrush - Grey Hawk
- Catherine Barroll - Mona Van Dyke
- Joely Collins - Daph
- Michael Cram - Bank Manager
- Roger Haskett - Michael Simms
- Venus Terzo - Lena Graf
- Venus Terzo - Linda Pratt
- Dean Marshall - Freddie Bates
- Scott McNeil - Judd
- Cameron K. Smith - Technician
- Norma Jean Wick - Anchorwoman
- Hrothgar Mathews - Yancey Lofton
- Hrothgar Mathews - Jake Lupo
- Colleen Winton - Dr. Peyton
- Tom Butler - Quincy Simon
- Tom Butler - Miles Devonian
- Brendan Beiser - Young Paxton Oaks
- Clarence Clemons - Leo Duquesne
- Duncan Fraser - Arthur Stephenson
- Duncan Fraser - Boyd Medcalf
- Sharon Heath - Barfly
- Rachel Hayward - Julianna 'Jolie' Morrow
- Rachel Hayward - Maureen Masters
- Woody Jeffreys - Young Dead Albert LaGatta
- John Moore - Dead Albert LaGatta
- James Purcell - Alan Ford
- Stella Stevens - Lorraine
- Kevin McNulty - Metcalf
- Kevin McNulty - Jack Falvo
- Trevor White - Young Bud Minnick
- Pamela Bach-Hasselhoff - Judy Ann Gibson
- David Neale - Colin Fisher
- David Neale - Clark Jellinek
- Eidan Hanzei - Sammy Chun
- William MacDonald - Harper
- Greg Thirloway - David Bowman
- Greg Thirloway - Martin Crown
- Belinda Metz - Shauna Diamond
- Mark Brandon - Walker Van Duzan
- Dean Paul Gibson - Richard Stirnweis
- Hiro Kanagawa - Otomo
- Hiro Kanagawa - Tashogi
- Brad Loree - Eric
- Brad Loree - Bob
- John MacDonald - Gary Pohl
- Deryl Hayes - Seabrooks
- Deryl Hayes - Sam Gideon
- Darcy Laurie - Trini
- Darcy Laurie - Mick Meloni
- Gabrielle Miller - Wanda Stirnweis
- Tamara Phillips - Constance Menzies
- Cynthia Preston - May Beth Andrews
- Christopher Shyer - Elliott Peoples
- Julianne Christie - Betsy Doyle
- Jo Bates - Shelley Levine
- Jo Bates - Andrea Goldberg
- Ken Kirzinger - Stan McGiles
- Barry W. Levy - Bill Stevenson
- Peter Bryant - Fred Solaro
- D. Harlan Cutshall - Cop
- Marya Delver - Marguerite
- Peter LaCroix - James Ellerbee
- Suleka Mathew - Sue Sanchez
- Jennifer McComb - Alicia Markham
- Sheelah Megill - Lanie Miller
- Ty Olsson - Ulysses
- Lindsay Bourne - Doctor
- Tom Cavanagh - Charles Bennett
- Dee Jay Jackson - Sergeant Daniels
- Ingrid Kavelaars - Sarah Bennett
- Udo Kier - Erich Geiger
- Colin Lawrence - Karl Mathers
- Peter Nicholas - Ashford
- Marco Roy - Tompkins
- Marc Baur - Art Pandell
- Richard de Klerk - Todd Doyle
- Rob Freeman - Max Doyle
- Scott Heindl - Bob
- David Lovgren - Brian LeShane
- Joe Maffei - Roy Eldridge
- Ron Sauvé - Nate LeShane
- Brent Stait - Simon LeShane
- Ingrid Tesch - Claudia Doyle
- Chilton Crane - Pamela Riggs
- Roger Barnes - Greg Garrison
- Adrien Dorval - Kerns
- Robert Moloney - Alan Simms
- Robert Moloney - Scott Ramsey
- Robert Fuller - Ethan Cole
- Brenda McDonald - Mrs. Fletcher
- Anthony Ulc - Midkiff
- Brock Johnson - Doggett
- Brock Johnson - Umberto
- Robert Wisden - Matt
- Steve Archer - Malloy
- Lenno Britos - Carlos Aguirre
- Ewan 'Sudsy' Clark - Vincent Brunings
- Danny Wattley - Drucker
- Danny Wattley - Tony
- Paul Hubbard - Matthew Carlisle
- Michael St. John Smith - Clay Toffler
- Richard Steinmetz - Richard Evans
- Karen Fineman - Alice Panshin
- Zak Santiago - Jerry Podwil
- Victor A. Young - Michael Farrelly
- Alex Zahara - Victor
- Will Sanderson - Harry Pollard
- Tim Henry - George Harris
- Tim Henry - Paxton Oaks
- Peter Wingfield - Giles Seton
- Kimberley Davies - Trudy
- Chris Duggan - Chip
- Adam J. Harrington - New Driver #1
- Jim Thorburn - Adam Graves
- Henri Brown - Lyle
- John Dadey - Cronin
- Ken Pogue - Jerome Midland
- Ken Pogue - Warren Keltner
- Benjamin Glenday - Cop #1
- Benjamin Glenday - Paramedic #1
- Stephen Dimopoulos - Garraty
- Stacy Grant - Katy
- Alex Kliner - Rabbi
- Richard Leacock - Rourke
- Ricki Dale - Nikki Brey
- Brian Arnold - Newsperson
- Michael Benyaer - Emile
- Michael Dobson - Sanducci
- R. Nelson Brown - Art Holcomb
- Carlos Gómez - Enrique La Paz
- Andrew Johnston - Dwyer
- Juan Llorens - La Paz Imposter
- Natassia Malthe - Trixie
- Jake T. Roberts - Brick
- Julieta Rosen - Vivica La Paz
- Kurt Max Runte - Jack Beaumont
- Anna Galvin - Mira McKenna
- Bob Morrisey - Grazen
- Jennifer Juniper Angeli - Clarice
- Lisa Bayliss - Suzanne Hartley
- Dorothy Fehr - Bouncer
- Joy Tanner - Angela
- Joy Tanner - Pearl
- Gary Hetherington - Mr. Kempler
- Annabel Kershaw - Carla Gale
- Mackenzie Phillips - Heidi Rosen
- Sarah Strange - Vicky Lee
- Douglas Arthurs - Baby Lyle
- Daniel Bacon - Commercial Director
- Corrie Clark - Cynthia
- Stephen Fanning - Evan Bridgeman
- David Fredericks - Desk Sergeant
- Kiara Hunter - Kendra
- Trevor Roberts - Arnie
- Patti Allan - Tilly Everhardt
- Norman Armour - Hudson Armstrong
- Nathaniel DeVeaux - Schaeffer
- Frank Ferrucci - Robert Ruiz
- Peter Flemming - Ken Guthrie
- Rob Morton - Sergeant Ungerford
- Govindini Murty - Nadia Farid
- Rick Burgess - Gilbert Rooks
- Jessalyn Gilsig - Alyssa
- Tom Heaton - Cyrus
- Peter Kent - Victor Murur
- JR Bourne - Seth Kincaid
- Conan Graham - David
- Biski Gugushe - Billy White
- Peter Hanlon - Evan Lindley
- Larry Holden - Grant Catlett
- Marcus Hondro - Ted Cannup
- Lisa LoCicero - Candace Lindo
- Michael Puttonen - Walsh / Bruno
- Emmanuelle Vaugier - Mitzi / Olga
- Eric Breker - Parker
- Patricia Harras - Denise Kaylen
- Paul McGillion - John Kane
- Alex Carter - Phil Dykstra / Dennis Pratt
- Alex Bruhanski - Bernie Polk
- Doris Chillcott - Elderly Woman
- Lesley Ewen - Diane
- John Payne - Buddy Winters
- Robert Rozen - Vitzhak
- John Tierney - Security Guard
- Faith Louissaint - Downtown Worker (uncredited)
- Bill Dow - Morty Woods
- Natasha Pavlovich - Ramona Woods
- Harry Van Gorkum - Lord Braxton
- Zack Ward - Crup
- Betty Linde - Phoebe Schuyler
- Laurie Paton - Marie Grimes
- Aurelio Dinunzio - Security Guard
- Howard Siegel - Lionel Davis
- Jud Tylor - Secretary
- Rita Whicker - Tour Guide
- Bob Wilde - Knight Cola Security Guard
- Demetri Goritsas - Alan Keefe
- Nicholas Harrison - Steve Korn
- P. Lynn Johnson - Doris Medcalf
- Reese McBeth - Ron DeSantis
- John Sampson - Dante Chiarello
- Richard Sargent - Paul McClain
- Brent Sheppard - Security Guard
- Jody Thompson - Rita Brooks
- Gordon Tipple - Doug Vale
- Dante Basco - Rishi Lama
- Eric Schneider - Mayor Cusack
- Jorgito Vargas Jr. - Victor
- Donna Yamamoto - Reporter
- Richard Yee - Khenpo Tenzing
- Sandra Nelson - Megan Davenport
- Natsuo Ishido - Kamiko Sato
- Ian Marsh - Ben Bradford
- Kevan Ohtsji - Akio Igawa
- Darryl Quon - Nezu
- Ron Robinson - Bodyguard
- Ron Selmour - Andrade
- Malcolm Stewart - Dan Harmon
- Natsuo Tomita - Kamiko Sato
- Peter Williams - Devon Zerbo
- Tom Braidwood - Larry
- Rochelle Bostrom - Jesse
- Jude Ciccolella - Marcus White
- Gus Trikonis
- Don Kurt
- Jeff Stein
- Mario Philip Azzopardi
- Joe Napolitano
- Michael Vejar
- Tommy Thompson
- Mitch Brian
- Howard Chaykin
Carrie-Anne Moss hace el papel de Stacy Taylor.
Michael Champion hace el papel de Erick Van Hook.
Callum Keith Rennie hace el papel de William T. Lennox.
Larry Holden hace el papel de Grant Catlett.
Josh Cruze interpreta a Madison en la serie.
William Russ interpreta a Townsend en la serie.
Patricia Charbonneau interpreta a Ella Keats en la serie.
Bruce A. Young interpreta a Administrator en la serie.
Alexandra Bokyun Chun interpreta a Lai en la serie.
Udo Kier interpreta a Erich Geiger en la serie.
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