- Mo Gilligan - Self
- Aisling Bea - Self
- Alexandria Ocasio-Cortez - Self (archive footage)
- Kiri Pritchard-McLean - Self
- Desiree Burch - Self
- Richard Branson - Self
- Phil Ellis - Self
- Greg Davies - Self
- Diane Abbott - Self
- Fiona Bruce - Self
- Colin Hoult - Anna Mann
- Ed Sheeran - Self
- Daryl D. Davis - Self
- Paul Chowdhry - Self
- Naomi Klein - Self
- Juan Mata - Self
- Julian Deane - Self
- Roisin Conaty - Self
- Fern Brady - Self
- Sarah Millican - Self
- Mae Martin - Self
- Jamie Oliver - Self
- Ed Gamble - Self
- John Oliver - Self
- Alesha Dixon - Self
- Jimmy Carr - Self
- Louis Theroux - Self
- Rose Matafeo - Self
- Derren Brown - Self
- Michelle Wolf - Self
- Chris O'Dowd - Self
- Joe Wilkinson - Self
- Rob Delaney - Self
- Jessica Knappett - Self
- Will Poulter - Self
- Jon Richardson - Self
- Jo Brand - Self
- Jon Ronson - Self
- Stacey Dooley - Self
- Joe Lycett - Self
- Richard Curtis - Self
- Lou Sanders - Self
- Stephen Merchant - Self
- Ant Middleton - Self
- Tyson Fury - Self
- Rapman - Self
- Kevin Smith - Self
- Elizabeth Banks - Self
- Carole Cadwalladr - Self
- Tan France - Self
- David Baddiel - Self
- Jack Black - Self
- Brian Cox - Self
- Emily Atack - Self
- Jamali Maddix - Self
- Seann Walsh - Self
- Armando Iannucci - Self
- Michael Patrick - Self
- Guz Khan - Self
- Jim Carrey - Self
- Konnie Huq - Self
- Eniola Aluko - Self
- Kerry Godliman - Self
- Daisy Haggard - Self
- Lady Leshurr - Self
- Kevin Bridges - Self
- Jessica Brown Findlay - Self
- Slim - Self
- Alex Horne - Self
- Rosie Jones - Self
- Dizzee Rascal - Self
- Brian Blessed - Self
- Matthew McConaughey - Self
- Tim Minchin - Self
- Richard Herring - Self
- Jamie Redknapp - Self
- Matt Forde - Self
- Joel Dommett - Self
- Matt Lucas - Self
- Rosie Dempsey - Joan
- Nicola Dempsey - Flo
- Katie Piper - Self
- Iain Stirling - Self
- Robert Peston - Self
- Janine Harouni - Self
- Daniel Ricciardo - Self
- Paul Sinha - Self
- David Harewood - Self
- Joy Crookes - Self
- Lucy Beaumont - Self
- Sophie Willan - Self
- Andrew Bird - Self
- Billy Connolly - Self
- Isy Suttie - Self
- Edgar Wright - Self
- Steven Pinker - Self
- Fatiha El-Ghorri - Self
- Evanna Lynch - Self
- Jordan Brookes - Self
- Kojey Radical - Self
- Susie Dent - Self
- Paul Merson - Self
- Harriet Dyer - Self
- Gabby Logan - Self
- Jordan B. Peterson - Self
- Self Esteem - Self
- Josh Widdicombe - Self
- Keanu Reeves - Self
- Carrie-Anne Moss - Self
- Fred Sirieix - Self
- Maisie Adam - Self
- Greta Thunberg - Self
- Jordan Gray - Self
- London Hughes - Self
- Sam Campbell - Self
- Matthew Holness - Garth Marenghi
- Russell Howard
Carrie-Anne Moss hace el papel de Self.
Russell Howard interpreta a Himself - Host en la serie.
Jim Carrey interpreta a Self en la serie.
Brian Cox interpreta a Self en la serie.
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