- Linda Armstrong - Sister Brigid
- Robert Daws - Dr. Gordon Ormerod
- Wendy Craig - Matron
- Diana May - Nurse Carol Selby
- John Axon - Mr. Nigel Harper
- Julian Ovenden - Dr. David Cheriton
- Anna Madeley - Nurse Samantha Beaumont
- Robert Cavanah - Adam Carnegie
- Damian O'Hare - Dr. Nick Burnett
- Glynis Barber - Jean McAteer
- Neil McDermott - Dr. Ralph Ellis
- Kari Corbett - Nurse Marian McKaig
- Michael Starke - Ken Hopkirk
- Natalie Anderson - Nurse Stella Davenport
- Gareth Hale - Jack Bell
- Ian Carmichael - T.J. Middleditch
- Paul Fox - Dr. Jeffrey Goodwin
- Paul Fox - Dr. Jeffrey 'Jeff' Goodwin
- June Whitfield - Esme
- Jan Harvey - Mrs. Annette Cheriton
- Barrie Rutter - John Briers
- Peter Lorenzelli - Charlie Travis
- David Walker - Alf Braidwood
- Raymond Pickard - Michael Westerlley
- Jimmy Akingbola - Corporal Frederick Collins
- Honor Blackman - Mrs. Lyons
- Gary Whelan - Dr. Arthur Clarkson
- Chris Gascoyne - Brian Harris
- Katy Cavanagh - Carol Buxton
- Sorcha Cusack - Sinead Donahue
- Martin Compston - Jeffrey Carpenter
- Steve Evets - Lester Marsh
- Phyllida Law - Daisy Crannagh
- Phyllis Logan - Lady George Fawcett
- Daniel Ryan - Ray Piper
- Prunella Scales - Red Admiral
- Paul Brooke - Dr. Marsden
- Trevor Peacock - Grandad
- Siobhan Finneran - Rita Hogg
- Shaun Dooley - Martin Tomlinson
- Caroline Clegg - Eileen Sanderson
- Lee Battle - Stan Sanderson
- Terence Harvey - Anthony
- Ryan Hawley - Phil Cooper
- Katherine Dow Blyton - Andrea Bennett
- Richard Burke - Len Tebbit
- Fiona Bruce - Mrs. Rutter
- Duncan Preston - John Rutter
- Eileen Davies - Mrs. Molly Lynson
- David Roper - Dennis Cording
- Rosy Clayton - Sheila Attercliffe
- Glenn Cunningham - Stuart Attercliffe
- Fred Ridgeway - Colin Nisbett
- Nicholas Blane - Mr. Alan Ferguson
- Randal Herley - George Heaton
- Eric Potts - Mr. Pearce
- Christopher Rozycki - Russian Captain
- Kate Rutter - Mrs. Baker
- Stacey Sampson - Susan Baker
- Geoffrey Banks - Vicar
- Peter Benson - Bernie Scripps
- Neil Boorman - Jonny Carol
- John De Main - Rob
- Rita May - Aunt Mary Graham
- George Neville - Station Master
- Mark Pepper - Gerry Hanrahan
- Philip Rowson - Steve Fairbank
- David Fleeshman - Don Waite
- Chris Fountain - Simon Waite
- Glynn Mills - Ambulance Man
- Richard Todd - Hugh Hirst
- Kenneth Colley - Bernard Hussey
- Francis Matthews - Dr. James Alway
- Bill Maynard - Claude Greengrass
- David Telfer - Fire Station Officer Mayfield
- Smug Roberts - MC
- Smug Roberts - Taxi Driver
- Caroline Carver - Eve Peterson
- Tristan Sturrock - Charles Dodds
- Derek Fowlds - Oscar Blaketon
- Alan Meadows - Lifeboat Cox
- Conrad Nelson - Ben
- David MacCreedy - Adam
- Steve Money - Mr. Bowman
- Christine Moore - Brenda Bowman
- Terence Mann - Bertie Hathaway
- John Lloyd Fillingham - Robert Harries
- Charlie Hardwick - Maggie Thomas
- Johnny Leeze - George
- David Lonsdale - David Stockwell
- Michael Begley - Patrick Barrie
- Katy Clayton - Harriet
- David Maybrick - Dave Kennoway
- Geoffrey Wilkinson - Caretaker
- Liam Fox - Ambulance Driver
- Bob Mason - Bill Cooper
- Ifan Meredith - Harry Arden
- Maggie O'Neill - Jane Cooper
- Alan Bird - George Dooley
- James Doherty - Philip Sutton
- John Elkington - Iain Lake
- Ronnie McCann - Vick Morris
- Madeleine Moffat - Mary Dooley
- Tricia Penrose - Gina Ward
- Phil Atkinson - Mr. Brice
- Janine Birkett - Mrs. Troughton
- Charles De'Ath - Simon Wake-Palmer
- Judy Hawkins - Miss Prosser
- Tom Hudson - Walter Metcalf
- Steve Garti - Andy
- Steve Garti - Harold Bardon
- Rebecca Johnson - Venetia Wake-Palmer
- Sally Adams - Madame Joyce
- Maggie Tagney - Mrs. Marjorie Gilbraithe
- Maggie Tagney - Mrs. Hedges
- Eileen O'Brien - June Smith
- Phil Corbitt - Bradley Lewis
- Judy Cornwell - Martha Hooke
- Gordon Langford Rowe - Fred Alton
- Graham McDuff - Howard Clark
- Niall O'Brien - Father Carroll
- Ann Rye - Lady Firminger
- Paul Loughran - Wilf Bishop
- Joanna Swain - Mrs. Fountain
- Liam Tobin - Tony
- Rebecca Atkinson - Suzannne
- Simon Bates - Lennie Lemar
- Cathy Breeze - Norma
- Alison Burrows - Mrs. Thomas
- Steve Huison - Mr. Thomas
- Keith Marsh - Ernest
- Bernard Wrigley - Albert
- John Sackville - Captain Daniel Waring
- Bobby Ball - John Wilson
- Anthony Bessick - Stan Nelmes
- Nicola Gardner - Sister Theresa
- Tara Moran - Helen Gardener
- Tony Pitts - Alec Glazer
- Malcolm Raeburn - Patterson
- William Simons - PC Alf Ventress
- Sue Devaney - Daisy Douglas
- Dave Hill - Joey Dudlow
- Adrian Hood - Aidan
- Marshall Lancaster - Matty
- Martin Reeve - Piggot
- Paul Shearer - Mr. Truman
- Andonis Anthony - Brian Esterleigh
- Thelma Barlow - Ada
- Nicky Evans - Eddie Spears
- Andrew Grose - Dom
- Jessica Harris - Shirley Baird
- Katherine Kelly - Tina Binnington
- Bill Rodgers - Harry
- Elspeth Charlton - Mary Briers
- Freddie Jones - Sebastian Fox-Kirby
- Christine Mackie - Mrs. Bain
- Lloyd Peters - Mr. Bain
- Ian Ralph - Ted
- Matthew Beard - Peter Blackwood
- Michael Bott - Mr. Blackwood
- Angela Catherall - Andrea
- Susan McCardle - Joy
- Simon Molloy - DI Shiner
- Julia Swift - Mrs. Blackwood
- Stephen Bent - Brian Tompkins
- Tenniel Evans - Mr. Silverwood
- Simon Hepworth - David Wilkinson
- Terence Hillyer - Tommy Green
- Duncan Marwick - Ray Dunlop
- Daphne Oxenford - Mrs. Silverwood
- Jeff Rawle - Banks
- Joanna Riding - Sheena Wilkinson
- Polly Maberly - Dr. Lucy Klein
- Morris Perry - Colonel Bradshaw
- Georgia Taylor - Ellen
- Kelly Wenham - Anna
- Alice Barry - Patient
- Orla Cottingham - Sally Hope
- John Flanagan - Harold Weatherill
- Frank Mills - Mr. Calder
- Gwyneth Powell - Bunty Weatherill
- Marcus Romer - Fireman
- Elizabeth Spriggs - Dolly Smith
- Dan Armour - Arthur Vardy
- Jim Norton - Rory
- John Branwell - Ray Archer
- Julie Glover - Mrs. Graham
- Graeme Hawley - Arthur Graham
- John Lightbody - Barry Price
- Samantha Power - Hazel Barton
- Jimmy Reddington - Ian Sadler
- June Broughton - Elsa Jones
- Eithne Browne - Vera Stubbs
- Francis Magee - Alex Heath
- Tony Mooney - Stan
- Derrick O'Connor - Patrick Maver
- Toby Sawyer - Spike
- Ned Irish - Old Man
- Ned Irish - Willie
- Paul Simpson - George Rae
- Seamus O'Neill - Len Edwards
- Seamus O'Neill - Mr. Norman Baker
- Chris Brailsford - Henry Carson
- Antony Byrne - Mr. Howarth
- Sarah Cattle - Carolyn Pickering
- Susan Cookson - Mrs. Howarth
- Barbara Marten - Assistant Matron Thelma Parker
- Angela Crow - Mabel
- Tim Dantay - Morrison
- Rachel Davies - Monkford
- Terrence Hardiman - Dr. Sedgewick
- Geoffrey Hutchings - Arthur Cordell
- Stuart Richman - Chesterton
- Emma Stansfield - Chrissy
- Duncan Barton - Andy
- Tracie Bennett - Sylvia
- Anna-Jane Casey - Amy
- Sean Chapman - Carl
- Jane How - Gloria
- Natalie Kennedy - Alison
- Jim Millea - Rescuer
- Hayley Tamaddon - Rosie
- Mary Cunningham - Hattie
- Sacha Parkinson - Polly Crunshank
- Jim Whelan - Norman Partridge
- Jim Whelan - Ernest Pocock
- Jamie Thurston - Tom
- Stephanie Waring - Georgie Wells
- Tim Wylton - Fred Jenkins
- Philip Martin Brown - Thomas Copley
- Jackie Downey - Mrs. Gilbert
- Richie Gibson - Neil Lambert
- Sue Jenkins - Mother Peter
- Gordon Kane - Mr. Patterson
- Claire Redcliffe - Sister Alice
- Cathy Sara - Denise Lambert
- Tony Haygarth - Father John
- Ted Holden - Eddie
- Richard Johnson - Johnny Lomax
- Lorraine Sass - Margaret Travis
- Alan David - Mr. Forbes
- Sean McKenzie - Terry Hopkirk
- Sean McKenzie - Cliff
- Emily Fleeshman - Carol Wallace
- Jacqueline Naylor - Annie Pailthorpe
- Mary Jo Randle - Fay Wallace
- Malcolm Tomlinson - David Wallace
- Susan Twist - Joan Travis
- Andy Abrahams - Lord Firminger
- Mark Stratton - Steward
- Steven Hillman - Bryan Duggins
- Steven Hillman - Denis Fallows
- Steven Hillman - Exeter
- Sharon Duce - Norma Smithson
- Peter Armitage - Bill Smithson
- Tony Britton - George Guthrie
- Jasper Britton - Paul Guthrie
- Karl Haynes - Eddie Frampton
- Robert Angell - Ian Hunt
- Chiké Okonkwo - Jermaine Johnson
- Robert Lawrenson - Tony Salter
- Amanda Hennessy - Maureen Salter
- Darryl Clark - Terry Buxton
- Tom Clarke Hill - Sgt. Archibald Wilson
- Michael Byrch - Motorbike Thief
- Kathryn Hunt - Jean Westerley
- Holly Scourfield - Joanna Atkins
- Annie Miles - Hilary Worthington
- Bernard Latham - Cyril Jenkinson
- Toby Walton - Neil Cutler
- Stephen Mapes - Gabriel
- Tony Monroe - Stan
- Blair Plant - David Hale
- Naomi Radcliffe - Ella Hale
- Dennis Blanch - Mr. Chambers
- Billy Mack - Liam O'Brien
- Clare McGlinn - Mrs. Carberry
- Bruce McGregor - Mr. Daley
- Charley Webb - Kathy Carberry
- Stephen Chapman - Roger Harcourt
- Hazel Douglas - Sybil Roper
- Jane Gurnett - Maggie Harcourt
- Samuel J. Hudson - Trevor Lee
- Bernard Gallagher - Alf Wilkinson
- Tom Mannion - Teddy Catchpole
- Elizabeth Rider - Miss Wilkinson
- Richard Ridings - Malcolm Hogg
- Tony Slattery - Phil Granger
- Norman Gregory - Jack Telford
- Ben Miller - Shane Brampton
- Sheree Murphy - Tanya Willson
- Philip Olivier - Jimmy Price
- Jack Sandle - Graham Wilson
- Robert Whelan - Arthur Powers
- Jacqueline Pilton - Pearl Norsby
- Jacqueline Pilton - Pearl
- Abena Ayivor - Alele
- Andrew Langtree - Sebastian Ellis
- Jeni Howarth Williams - Sheila Willis
- Simon Ashley - Driver
- Emma Ashton - Kathy Rae
- Emma Ashton - Beryl Oatridge
- Sarah Barrand - Dorcus
- Samuel Kane - Rick
- Matthew Lewney - Brownlee
- Jorden Bennie - Jason Hodges
- Philip Bird - Brian Pinner
- Sally Carman - Susan Hodges
- Judy Flynn - Lesley Pinner
- Julian Kay - Colin Hodges
- Lauren Leak Smith - Cassie Beattie
- Rachel Leskovac - Marie Beattie
- Tony Maudsley - Jimmy Beatie
- Jacqueline Boatswain - Safi
- Stefan Booth - Tom Firth
- Lucy Robinson - Lady Isabella Martindale
- Kenneth Cope - Albert Trent
- Jonathan Mason - Simon Etterick
- Andrew Readman - Trevor Bryant
- Angela Thorne - Dorothy Bryant
- Amelia Curtis - Nurse Catherine Deane
- Daymon Britton - Nick Metcalfe
- Elianne Byrne - Lily Metcalfe
- Mark Cameron - Billy Yates
- Laurie Hagen - Therese Duval
- Anne Hornby - Julia
- Martin Walsh - Terry Pendleton
- Christian Cooke - Bobby Horrocks
- Charles Dale - DS Slingsby
- Paul Opacic - Gideon Bradley
- Ted Robbins - Ted Skinner
- Joanne Venet - Mrs. Skinner
- Myfanwy Waring - Jessica
- Sam Callis - Dr. Mike Banner
- Marie Critchley - Agnes Corbett
- Kevin Doyle - Ralph Fleming
- Mark Jardine - Mark Long
- Paul Popplewell - Chris Nugent
- Paul Popplewell - Marlon Barratt
- Rachel Smith - May Tomlinson
- Sean Ward - Ray Fuller
- Sean Ward - Jamie Parson
- George Costigan - Hugh Etheridge
- Freda Dowie - Dora Rigby
- Jake Fitzpatrick - Stephen Graham
- Alison Mac - Kathy Graham
- Olwen May - Sheila
- Tom Charnock - Ray
- Jack Deam - Sam
- Caroline Harding - Diane Fletcher
- Matthew McNulty - Stan
- Sydney Wade - Laura
- Tara Berwin - Katie Ormerod
- Andrew Dunn - Billy Taylor
- Michael Jayston - Henry Appleton
- Elizabeth Kelly - Edith Taylor
- Paul Warriner - Dudley Hulbert
- Lucy Black - Daisy Poole
- Daniel Casey - David Hibbert
- Colin Connor - Taxi Driver
- Clare Kerrigan - Heather Seddon
- Graham McTavish - Anthony Poole
- Emma Rydal - Alice Hibbert
- Jarrod Cooke - Tony
- Angela Forrest - Sadie Worsley
- Gerard Horan - Ned Worsley
- Jane Lowe - Mrs. Smythe
- Emma Bispham - Teresa Fisher
- James Greene - Dermot Sheahan
- Serge Soric - George Romain
- Stuart Wolfenden - Mark Fisher
- Robert Blythe - Eric Darnby
- Emma Lowndes - Penny Darnby
- Martha Myers Lowe - Karen Darnby
- Andrew Westfield - Captain
- Ray Ashcroft - Sid
- Alasdair Craig - Alastair Felix
- Clara Darcy - Vanessa Felix
- Claire King - Lucy Bayliss
- Joshua Miles - Cadet
- Mark Noble - Aiden Bayliss
- Victoria Scarborough - Claire Massey
- Rachel Warren - Estelle
- Judith Barker - Doris Nightingale
- Berwick Kaler - Eric Fogle
- Rocky Marshall - Lorenzo Dannini
- Sally Ann Matthews - Ellen Dannini
- Madlena Nedeva - Maria Dannini
- Vincenzo Nicoli - Tony Dannini
- Peter Ash - John Stemford
- Stephanie Dooley - Kay Bradley
- Margaret Jackman - Iris
- Eve Steele - Janet Armley
- Meryl Hampton - Examiner
- Gemma Harvey - Woman
- Daniel Jillings - Man
- Rosemary Leach - Hester Hindmarch
- Craig Shepherd - David
- James Baxter - Simon Watts
- Brian Blessed - Sir Edward Fawcett
- Sarah Beck Mather - Nurse Susie Dixon
- Sarah Beck Mather - Student Nurse Susie Dixon
- Sarah Beck Mather - Susie Dixon
- Tom Georgeson - Duncan Crosby
- Ken Bradshaw - Reg Statham
- Brittany Ashworth - Siobhan O'Grady
- Sian Breckin - Judith Ure
- Rosalind Ayres - Grace Parmitter
- William Travis - Gary Jackman
- Keith Clifford - Walter Bannister
- Oliver Farnworth - Neville Cartwright
- Katherine McGolpin - Mandy McMorrow
- Caroline O'Neill - Ruth Thake
- Niall Refoy - Stewart McMorrow
- Sue Wallace - Eileen Bannister
- Oliver Beamish - Father McCarthy
- Heather Bleasdale - Meg Myerson
- Lisa Dwyer Hogg - Moira Kilgannon
- Lisa Howard - Jane Tillotson
- James Quinn - Peter Turner
- Angela Lonsdale - Anna Whenby
- Michael Hodgson - Alistair Whenby
- Billy Boyle - Father Maguire
- Mairéad Conneely - Niamh O'Malley
- Georgina Mellor - Miss Todd
- Dominic Rickhards - Roy Belkin
- Daragh O'Malley - Niall Donahue
- William Ilkley - Chief Fire Officer
- William Ilkley - Officer Pratchet
- William Ilkley - Officer Pratchett
- Monica Sayers - Mrs. Wong
- Matthew Steer - Paul Harman
- Amy Morgan - Julie Woolton
- Thomas Aldersley - Mr. Morgan
- Rhiannon Howden - Ellie Morgan
- Glenda McKay - Mrs. Morgan
- Gabrielle Drake - Margo Price
- Stephen Moore - Howard Price
- Susan Hampshire - Elizabeth Middleditch
- Josh Moran - Lionel Cookston
- Frances Tomelty - Rosemary Briggs
- Anna Brewster - Cynthia Grant
- Lorraine Cheshire - Mrs. Hastings
- James Daffern - Jimmy Barratt
- Rachel Mitchem - Pam Fuller
- Danny Szam - Thomas Palmer
- Travis Yates - Brian Hastings
- Paul Gabriel - Sergeant Fuller
- Adam Allfrey - Mr. Smith
- Richard Hansell - Edgar Plumley
- Charles McCurdy - Underwood
- Will Tacey - Philip Plumley
- Alwyne Taylor - Diane Plumley
- John Bowe - Max Freeman
- Jenny Funnell - Anna Freeman
- Lisa Millett - Daniella Galliani
- Abbie Salt - Denise Mount
- Colin Wells - Duncan Fuller
- Craig Cheetham - Graf Spee
- James Mair - Ajax
- Martin Oldfield - Magistrate
- Catherine Tyldesley - Sheila Blunt
- Benjamin Whitrow - Professor Farrow
- Guy Burnet - Lenny Lomax
- Trevor Dwyer-Lynch - Eddie
- Andrew Ellis - Jonno
- Adam Fogerty - Bernie
- Jodie McEnery - Rita
- Emily Corselli - Alison
- James Faulkner - Sir Charles
- Lauren Drummond - Student Nurse Faye Clark
- Lauren Drummond - Student Nurse Fay Clark
- Daniel Fine - Tom
- Peter Gunn - Harry
- Annie Hulley - Dolly
- Simon Lawson - Dennis
- Emma Pollard - Helena
- Paul Copley - Nesbitt
- Gerard Fletcher - DS Morrell
- Stuart McGugan - Ken Letham
- George Irving - Terence Mavers
- Elaine Glover - Shirley Bennett
- Roger Morlidge - Geoff Bennett
- Matt Stubbs - Dave Bennett
- Jo-Anne Stockham - Sister Assumpta
- Samuel Barnett - Joe Steeples
- Basienka Blake - Briony Wellborn
- Charlie Brown - Barnie Wilson
- Fine Time Fontayne - Nobby Jepson
- Carol Holt - Muriel Thorne
- Kayleigh Stephenson - Rosie Hipwell
- Christopher Villiers - Frank Wellborn
- Alan Wareing
- Neil Adams
- Ian Barber
- Keith Boak
- John Greening
- Dominic Keavey
- Patrick Melanaphy
- Jane Hollowood
- Mark Holloway
- Jonathan Critchley
- Deborah Cook
- Marc Pye
- Jonathan Rawlinson
Damian O'Hare interpreta a Dr. Nick Burnett en la serie.
Janine Birkett hace el papel de Mrs. Troughton.
Adam Fogerty interpreta a Bernie en la serie.
Michelle Hardwick interpreta a Lizzie Kennoway en la serie.
Andy Wear interpreta a Alun Morris en la serie.
Denis Lill hace el papel de Mr. Rose.
Amy Robbins interpreta a Dr. Jill Weatherill en la serie.
Linda Armstrong hace el papel de Sister Brigid.
Robert Daws interpreta a Dr. Gordon Ormerod en la serie.
Wendy Craig interpreta a Matron en la serie.
Capítulo disponible en las siguientes plataformas:
