- Dan Blocker - Little Willie
- Ethel Merman - Mother Hughes
- Peter Falk - Colonel Hush-Hush
- Chanin Hale - Daisy June
- Jane Morgan - Jane Morgan
- Alan Copeland - Alan Copeland
- Ed Sullivan - Himself
- Helene Stanton - Fairy Godmother
- Wilda Taylor - Dancer in Freddie's Dream
- Jana Lund - Daisy June
- Todd Martin - Bank Clerk
- Harold Peary - Mayor
- Robert Carson - Mr. Hoity
- Elaine Joyce - Secretary
- Lou Rawls - Self - Guest Vocalist
- Peggy Rea - Miss Katie - Waiters' Boss
- Billy Beck - Fred the Waiter (uncredited)
- Bess Flowers - Restaurant Patron (uncredited)
- Mickey Rooney - Self / Perry Masonjar
- Herb Vigran - The Judge
- Herb Vigran - Guest
- Herb Vigran - Storekeeper
- Herb Vigran - Man on CBS Studio Tour
- Mike Mazurki - Max the Black (Pirate)
- Tennessee Ernie Ford - Self
- Tennessee Ernie Ford - Self / Loser Lumpkin
- Connie Sawyer - Woman in Blue Feathers
- Norma Varden - Wealthy Art Patron
- Agnes Moorehead - Self / Bertha Bluenose
- William Demarest - Senator Burnside
- Sam Flint - Colonel Tracy
- George O'Hanlon - US Corporal
- Robert Armstrong - Lt. Flanagan
- Chester Morris - Tony
- Edgar Bergen - Doctor-Olio Spot
- Lon Chaney Jr. - George
- Lon Chaney Jr. - Mad Scientist
- Lon Chaney Jr. - Ug - Prehistoric Cave Man
- Lon Chaney Jr. - Lon Chaney
- Lon Chaney Jr. - Sgt. Williams
- Eve McVeagh - Mrs. Appleby
- Amanda Blake - Beverly Fairfield
- Taylor Holmes - Judge Taylor Holmes
- Taylor Holmes - Judge
- Art Gilmore - Announcer
- Art Gilmore - Self - Announcer (voice)
- Art Gilmore - Announcer (voice)
- Art Gilmore - Self - Announcer
- Art Gilmore - Announcer / Game Show Emcee
- Art Gilmore - Self - Announcer/Walter Crankcase (voice)
- Art Gilmore - Announcer / Newscaster
- Art Gilmore - Announcer / Radio Disk Jockey (voice)
- Cesar Romero - Big Bill - Racketeer
- Ralph Sanford - the Admiral
- Ralph Sanford - Graft collector
- Marshall Reed - Kid Jackson
- Marshall Reed - Ed
- Marshall Reed - U.S. Marshal
- Marshall Reed - Jim Broderick
- Marshall Reed - Mr. Toity
- Carleton Young - Col. Hopkins
- Gene Autry - Self
- Lester Matthews - Sylvester
- Kathryn Card - Maw Kadiddlehopper
- Kathryn Card - Gert's Mother
- Kathryn Card - Ma Kadiddlehopper
- Kathryn Card - Priscilla's Mother
- Kathryn Card - Gertie's Mother
- Mary Wickes - Clara Appleby
- Mary Wickes - Self
- Nancy Walker - Gertie - Bolivar's Girlfriend
- Nancy Walker - Self
- Gerald Mohr - Scarface
- Rod Serling - Self / Cameo (uncredited)
- Rosemary DeCamp - Abigail Van Clive
- Phil Harris - Guest
- Paula Kelly - Guest Vocalist
- Cedric Hardwicke - Dr. Umlauf
- Cedric Hardwicke - Company Vice President J.R. Williams
- Byron Foulger - Member of Temperance League (uncredited)
- Horace McMahon - Member of Bar Association (uncredited)
- Maudie Prickett - Woman from PTA
- Maudie Prickett - Member of Temperance League (uncredited)
- Maudie Prickett - Mrs. Narrow
- Maudie Prickett - Mrs. Gould
- Maudie Prickett - Housewife
- Richard Chamberlain - Clarence Narrow
- Richard Reeves - Railroad Cop
- Beverly Washburn - Cabina
- Dick Wessel - CPO Delaney - USS Farragut
- Dick Wessel - Assistant (uncredited)
- Vikki Carr - Self
- George Gobel - Richard Cornwall III
- George Gobel - Self / Christopher Columbus
- George Gobel - Mr. Winkle
- George Gobel - Dr. Stroodel
- George Gobel - Tooloose Latrec
- George Gobel - George Goodbody
- George Gobel - Dr. Ben Cagey
- George Gobel - Self / Egbert the Amnesiac
- George Gobel - Self / Horace the Henpecked Husband
- George Gobel - Self / Alexander Ragtime / Jed Dinglejumper
- Marion Ross - Elizabeth - Sir Reginald's daughter
- Marion Ross - Patricia Westerbrook
- Marion Ross - Patricia Winterbrook
- Ed Wynn - Muggsy
- Ed Wynn - Fairy Godfather
- Ed Wynn - Self
- Ed Wynn - Guest Host
- Ed Wynn - Self / Colonel Jungle-Rot Freeloader
- Johnny Carson - Knight Who Makes Point of Order
- Frank Wilcox - Mr. Bailey - TV Network Vice-President
- Frank Wilcox - Warden
- Frank Wilcox - Prison Warden
- Jack Jones - Self / Professor Jones
- Jack Jones - Harold Handkisser
- Jack Jones - Self / Johnny Applecore
- Peter Lorre - Mad Scientist
- Peter Lorre - Boris - Chief Spy
- Peter Lorre - King Zurium
- Anna Maria Alberghetti - Self / Juliet Capulet
- Sol Gorss - Knight
- Sol Gorss - Supporting player
- Sol Gorss - Supporting Player
- Charlotte Knight - Dr. Cagey's Washerwoman Mother
- Karen Morrow - Self
- Frankie Valli - Self
- Herschel Bernardi - Muggsy - a Hobo
- Dorothy Neumann - Old Woman
- Dorothy Neumann - Masquerade Ball Society Snob
- Dorothy Neumann - Secy in Pre Show Skit / Old Lady at Gas Station-Silnt Spot
- Dorothy Neumann - Woman on Parole Board
- Dorothy Neumann - The Butcher's Daughter
- Dorothy Neumann - Sorcerer
- Dorothy Neumann - Old Woman From Stagecoach
- Dorothy Neumann - Schoolmarm
- Art Linkletter - Hobo (uncredited)
- Cara Williams - Raggedy Ann
- Cara Williams - Clara Appleby
- Dale Robertson - Robinson Crusoe
- Alan Mowbray - Explorer Radccliffe
- Phyllis Diller - Clara - the Dean's Daughter
- Phyllis Diller - Killer Diller
- Phyllis Diller - Self / BoBo Van Beacon
- Phyllis Diller - Self / Greta Gargoyle
- Jack Palance - Self
- Bob Hope - Self - Cameo
- Nipsey Russell - Self /Officer Nipsey Ralston
- Nipsey Russell - Self
- Phyllis Coates - Supporting Sketch Player
- Lee Aaker - Wilbur Van Owen
- Lola Albright - Foreign Spy
- Lola Albright - Priscilla
- Lola Albright - Guest
- Len Lesser - Killer McBumpoff
- Len Lesser - Bum / Slippery Scottty Sutton
- Len Lesser - Big Mike Miller
- Len Lesser - Legs
- Len Lesser - Percival Cutthroat - Pirate with Hook
- Robert Vaughn - Victor Virtue
- Florence Lake - Tessie
- Florence Lake - Senior Citizen
- Doris Singleton - Mrs. Cavendish
- Harold Gould - General Important
- Harold Gould - Dr. Knockitoff
- Eve Brent - Wife / Silent Spot
- Michael Stefani - Tom Clark
- Jane Wyman - Clara Crowley Appleby
- Tim Conway - Phil Fumble
- Jamie Farr - Snorkel
- Jamie Farr - Lazlo - Henchman
- Jamie Farr - Seaman First Class Snorkel
- Ben Welden - Ben the Henchman
- Ben Welden - Eddie
- Ben Welden - Baby Face Hogan
- Ben Welden - Big Bill's henchman #1
- Ben Welden - Badman
- Audrey Meadows - Gloria Castle
- Audrey Meadows - Mrs. Cavendish
- Audrey Meadows - Self / Dr. Blodgett
- John Forsythe - Millionaire's Son
- Buddy Lewis - George's Poker Buddy / Bank Janitor -- Silent Spot
- Buddy Lewis - Police Officer
- Buddy Lewis - Muggsy - a Hobo
- Buddy Lewis - Ratsy - a Hobo
- Michele Lee - Peaches Laverne
- Frank Albertson - General Scott
- Marjorie Bennett - Schoolteacher / Silent Spot
- Marjorie Bennett - Woman Mailing Package
- Marjorie Bennett - Nurse
- Marjorie Bennett - Duchess of Nottingham
- Marjorie Bennett - Wedding Reception Guest
- Marjorie Bennett - Miss Jenkins - Red's Maid
- Mercedes McCambridge - Clara Appleby
- Janis Paige - Self
- Janis Paige - Mrs. Cavendish
- Janis Paige - Hatta Mari
- Janis Paige - School Teacher
- Anne Jeffreys - Hatti Mari
- Paula Kelly - Self
- Peter Brocco - Fingers Malone
- Eddie Marr - Milkman
- Eddie Marr - Robber
- Eddie Marr - Hot Dog Vendor
- Gavin Gordon - Manager
- Gavin Gordon - King Arthur
- Gavin Gordon - Sam's Lawyer
- Almira Sessions - Charity Woman
- Almira Sessions - Woman Watching Dancers-Star
- Desi Arnaz - Self
- Diahann Carroll - Self
- Harold J. Stone - Sketch Player
- Milton Frome - Cruise Ship's Captain
- Milton Frome - Campaign Advisor Kirby
- Milton Frome - XYZ-TV Network President
- Milton Frome - Navy commander
- Milton Frome - Self - George's Boss
- Milton Frome - Movie Director
- Milton Frome - Self - George Smythe
- Milton Frome - Kenneth
- Milton Frome - Stanley Starmaker
- Milton Frome - Store Manager
- Milton Frome - Joe - Thug
- Marvin Kaplan - Self
- Marvin Kaplan - Self/Alfred Pinzmetal
- Olive Sturgess - Elaine - Sally's sister
- Mary Treen - Girl in Park
- Maurice Marsac - Waiter
- Allen Jenkins - Muggsy
- Eddie Parker - Cop
- Hy Averback - Colonel
- Hy Averback - British Colonel
- Milton Berle - Self / Duke No-Good
- Grady Sutton - Torture Device Customer
- Jean-Paul Vignon - Self
- Phyllis McGuire - Self
- Don Brodie - Muggsy - a Hobo
- June Foray - Baby-like Cry (voice)
- Eva Gabor - Tanya the Spy
- Boris Karloff - Professor Townsend (Spy)
- Michael Ross - Restaurant customer
- Michael Ross - Bruce - Elaine's other suitor
- Michael Ross - Big Jim McLane
- Michael Ross - Bus Driver
- Henry Kulky - Self/Sgt. Flannagan
- Henry Kulky - Jerry
- Arte Johnson - Census Taker
- John Wayne - Self
- John Wayne - Self (uncredited)
- John Wayne - Self - Rooster Cogburn
- Jackie Gleason - Reginald van Gleason III / cameo
- Victoria Carroll - Homeless Mother / Silent Spot
- Ellen Corby - Little Old Lady
- Telly Savalas - Self / Tex
- Pat Carroll - Mrs. Shore
- Pat Carroll - Clara Appleby
- Pat Carroll - Killer's Manager / Mrs. Lump Lump
- George E. Stone - Arnold
- Joseph Mell - Zookeeper
- Gene Raymond - General
- Dick Simmons - Mr. East-Station Owner
- Polly Bergen - Sally Suey
- Polly Bergen - Clara Appleby
- Polly Bergen - Self / Myrtle
- Reta Shaw - Myrtle's Mother
- Burt Mustin - Old Man Gramps
- Douglas Fowley - Pete
- Raymond Hatton - Buck
Cesar Romero hace el papel de Big Bill - Racketeer.
Peter Falk interpreta a Colonel Hush-Hush en la serie.
Peter Lorre interpreta a Boris - Chief Spy en la serie.
Carleton Young hace el papel de Col. Hopkins.
Sol Gorss hace el papel de Supporting player.
Boris Karloff interpreta a Professor Townsend (Spy) en la serie.
Gavin Gordon hace el papel de Manager.
Mickey Rooney hace el papel de Self / Perry Masonjar.
Robert Armstrong interpreta a Lt. Flanagan en la serie.
Jack Palance hace el papel de Self.
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