- Robert Foxworth - Race Bannon (voice)
- Jennifer Hale - Jessie Bannon (voice)
- Jennifer Hale - Kate (voice)
- Quinton Flynn - Jonny Quest (voice)
- Quinton Flynn - Sonar Man / Guard (voice)
- Rob Paulsen - Hadji Singh (voice)
- Rob Paulsen - Soldier 1 (voice)
- Carl Lumbly - Colonel William Marcus (voice)
- Jeffrey Tambor - Black Jack Lee (voice)
- Bruce Locke - Kumar Mukharno (voice)
- Jeff Bennett - Gun Captain (voice) / Diver (voice)
- Theresa Saldana - Estella (voice)
- Thomas Gibson - Paul Mornay (voice)
- Mayim Bialik - Julia (voice)
- Mayim Bialik - Lucy (voice)
- Lucy Liu - Melana (voice)
- Charles Napier - Hinkle (voice)
- Edward Winter - President (voice)
- David Ackroyd - Ezekiel Rage (voice)
- Andreas Katsulas - Stephano DePace (voice)
- Robert Ito - President Horkarno (voice)
- Mark L. Taylor - Brother James (voice)
- Philip Maurice Hayes - Deke (voice)
- Paxton Whitehead - Commander (voice)
- Richard Libertini - Commissioner (voice)
- Nick Chinlund - Temple (voice)
- Greg Burson - Corbin (voice) / Sanderson (voice)
- Julian Sands - Kreed (voice)
- Michael Dorn - Tala (voice)
- Peter Jurasik - Alan Zegler (voice) / Williams (voice)
- Ed Gilbert - Badur (voice)
- Ed Gilbert - Hakim (voice) / Salim (voice) / Haresh (voice)
- Ed Gilbert - Professor Scheele (voice)
- Soon-Tek Oh - General Yala (voice)
- Michael Bell - Ezekiel Rage (voice)
- Michael Bell - Karst (voice)
- Michael Bell - Dr. Forbes (voice)
- Peter Strauss - Lab Guard (voice)
- Robert Cait - Base Op (voice) / Checkpoint Guard (voice)
- Nick Tate - Pirate (voice)
- Nick Tate - Darcy (voice)
- Arye Gross - Matthews (voice)
- Dean Jones - Dr. Karel (voice)
- George Kennedy - General Axton (voice)
- Dorian Harewood - Officer (voice)
- Dorian Harewood - Tigari (voice)
- Mari Weiss - Lady Caroline (voice)
- Ed Asner - Von Romme (voice)
- Jerry Doyle - Corey (voice) / Felipe (voice)
- Paul Eiding - Bennett (voice)
- Harve Presnell - Doug (voice)
- Tara Strong - Kazrina (voice)
- Tara Strong - Irina Kafka (voice)
- Michael Stanton - Hank (voice)
- Frank Welker - Bandit / Professor Erikson (voice)
- James Barbour - Andrew (voice)
- Brian Tochi - Professor Ken Otsuki (voice)
- Brian Tochi - Techi #1 (voice) / Terrorist Pilot (voice)
- Michael Carven - Arnaud (voice)
- Troy Evans - Sgt. Kenton (voice)
- Dee Bradley Baker - Dr. Vedder (voice)
- Dee Bradley Baker - Williams (voice)
- Mary Gregory - Mrs. Adrian (voice)
- Jennifer Lien - Elise (voice)
- Kevin Michael Richardson - Computer Voice (voice) / Sentry #2 (voice) / Tech #1 (voice)
- Kevin Michael Richardson - Segala (voice)
- Ian Ogilvy - Dr. Smallwood (voice)
- Nicholas Smith - Quentin (voice)
- Sarah Douglas - Mrs. Cadbury (voice)
- Don Reed - Ngama (voice)
- Shari Belafonte - Diana Cruz (voice)
- Ahmet Zappa - Policeman (voice)
- Darleen Carr - Abby (voice)
- Darleen Carr - President Stasny (voice)
- Darleen Carr - President (voice)
- Nancy Linari - Julia (voice)
- Nancy Linari - Neela (voice)
- Earl Boen - Officer (voice) / Stage Coach Guard (voice)
- Earl Boen - Dr. Forbes (voice)
- Earl Boen - Kyle (voice)
- Ric Young - Dja'Lang Mukharno (voice) / Mr. Mahasson (voice)
- Helene Udy - Julie (voice)
- Helene Udy - Natasha Rastova (voice)
- Helene Udy - Belle (voice)
- Don Harvey - Milos Duncek (voice)
- Tim Lounibos - N'Joman (voice)
- Tim Lounibos - Dr. Hatani (voice)
- James Shigeta - Inspector Mantjur (voice)
- James Shigeta - Dr. Yamashiro (voice)
- Brock Peters - The Shaman (voice)
- Brock Peters - Masai (voice)
- Jim Cummings - Florid Face (voice) / Yagor (voice) / Captain James (voice)
- Jim Cummings - Harpooner (voice) / Planesman (voice)
- Jim Cummings - Lacey (voice) / Pirate (voice)
- Clyde Kusatsu - Dr. Zin (voice)
- Peter Renaday - High Lama (voice)
- Peter Renaday - Kane (voice)
- June Angela - Anaya (voice)
- Michael Gough - Jacobi (voice) / Eric (voice)
- Tasia Valenza - Jade (voice)
- Clive Revill - Harpooner (voice) / Medical Officer (voice)
- Clive Revill - Hunter #1 (voice) / Trench (voice)
- Nancy Travis - Captain Spencer (voice)
- Nick Jameson - Sultan Vikram (voice)
- Nick Jameson - Himalayan (voice) / Sherpa (voice)
- Nick Jameson - Leif (voice)
- Tristan Rogers - Hawkins (voice)
- Charlie Adler - Rawlings (voice)
- Lewis Arquette - Civilian (voice) / Driver (voice)
- Mark Hamill - Vostok (voice)
- Mark Hamill - Eldoradoan (voice)
- Mark Hamill - General Vostok / Guard (voice)
- Carolyn Seymour - Aleutian Woman (voice) / Mother (voice)
- Jim Meskimen - Torgeson (voice)
- Jim Meskimen - Black Jack Lee Impostor (voice)
- Jim Meskimen - Dr. Vedder (voice)
- Jim Meskimen - Havel (voice) / Conn (voice)
- Clancy Brown - Frederico (voice) / Francois (voice)
- Clancy Brown - Colonel Nikolai / Guard (voice)
- Maurice LaMarche - Pasha (voice)
- Michael Horse - Ames (voice)
- Michael Horse - Eskimo (voice)
- Haven Hartman - Karla (voice)
- Chick Vennera - Gustavo Arollo (voice)
- Chick Vennera - Lorenzo (voice)
- Chick Vennera - Walker (voice)
- Larry Moss - Skipper (voice)
- George Ball - Announcer (voice)
- Megan Cavanagh - Julia (voice)
- Jan Rabson - Avary (voice) / Donaldson (voice)
- B.J. Ward - Iris the Computer (voice)
- Matthew Arkin - Petrov / Sentry #1 (voice)
- Gregg Berger - Captain Rossanov / Guard (voice)
- Joseph Barbera
- William Hanna
Don Harvey hace el papel de Milos Duncek (voice).
Mark Hamill interpreta a Eldoradoan (voice) en la serie.
Jennifer Lien interpreta a Elise (voice) en la serie.
Brock Peters interpreta a Masai (voice) en la serie.
Harve Presnell hace el papel de Doug (voice).
Jeffrey Tambor interpreta a Black Jack Lee (voice) en la serie.
Michael Dorn hace el papel de Tala (voice).
Lucy Liu interpreta a Melana (voice) en la serie.
Earl Boen hace el papel de Kyle (voice).
Robert Patrick hace el papel de Race Bannon (voice).
Capítulo disponible en las siguientes plataformas:
