- Morgan Woodward - Shotgun Gibbs
- Jack Ging - Johnny O'Rourke
- Ellen Corby - Mrs. Jane McGill
- Grady Sutton - Store Clerk
- Bob Steele - Deputy Marshal Sam (uncredited)
- Ken Mayer - Dapper Courtney
- John Pickard - Johnny Ringgold
- Phillip Pine - John Wesley Hardin
- Angie Dickinson - Ann Drew
- Douglas Fowley - Doc Holliday
- Douglas Fowley - Doc Fabrique
- Douglas Fowley - Grandpa Logan
- Douglas Fowley - Dr. John H. Holliday
- Walter Reed - Turner Ashby
- Don Dillaway - Mr. Hildreth
- Ray Montgomery - Virgil Earp
- Warde Donovan - Jed Lorimer
- Sue George - Sally Davis (uncredited)
- Robert Ellis - Pvt. Crenshaw
- Harry Harvey - Telegrapher (uncredited)
- Harry Harvey - Man Talking to Swamper (uncredited)
- Harry Harvey - John H. Brodus
- Harry Harvey - Storekeeper A.P. Whittle
- Fred Graham - Mel (uncredited)
- Robert Bray - Deputy Sam Leggitt
- Selmer Jackson - Mayor Hoover
- Denver Pyle - Ben Thompson
- Denver Pyle - Hoss Mackey
- Roy Roberts - A.H. 'Shanghai' Pierce
- Kay E. Kuter - Trask - Pierce's Henchman
- Dale Van Sickel - Durango
- Dale Van Sickel - Tough (uncredited)
- Steve Raines - Hoodlum (uncredited)
- Dick Cherney - Bartender (uncredited)
- Leo Gordon - Miggles Hannegan
- Barney Phillips - Lou Rickabaugh
- Norman Alden - Johnny Ringo
- Frank Hagney - McLowery Gunman (uncredited)
- Frank Hagney - Bartender (uncredited)
- Charles H. Gray - Lukens - Gunman After Masterson
- James Coburn - Buckskin Frank Leslie
- George Eldredge - Miles Lenihan
- George Eldredge - Cap Jamison (uncredited)
- Damian O'Flynn - Judge Tobin
- Damian O'Flynn - Dr. Goodfellow
- Damian O'Flynn - Doc Fabrique
- Damian O'Flynn - Keeno McGee
- Damian O'Flynn - Judge Tobin AKA Judge Rope Tobin
- Damian O'Flynn - Mannen Clements
- Sam Flint - Judge Jewett
- Sam Flint - Judge Jewitt
- Sam Flint - Stableman
- Sam Flint - Fred White
- Sam Flint - Marshal Fred White
- Sam Flint - Stableman Ruger
- Sam Flint - Stableman Gruber
- Sam Flint - Old Man
- Sam Flint - Dad Lenhart - Stableman
- Sam Flint - Mr. Gale (uncredited)
- Sam Flint - Arizona Transport Worker (uncredited)
- Sam Flint - Spouter
- Sam Flint - Mr. Borden (uncredited)
- Sam Flint - Limestone Parker
- Sam Flint - Judge Jewitt (uncredited)
- Larry J. Blake - Mr. Kenton (uncredited)
- Larry J. Blake - Dusty Wilson
- Tris Coffin - Col. Grayson
- Zon Murray - Sam Newton
- Zon Murray - Gus Loring
- Grant Withers - Gus Andrews
- Grant Withers - Miles Breck
- Rita Lynn - Bonnie Dawson AKA Mrs. Tom Whiting
- Don Kennedy - Bill Tilghman
- Paul Brinegar - Jim Kelley
- Paul Brinegar - Jim Kelley (uncredited)
- Paul Brinegar - Jim Begley
- Frank Mills - Bartender (uncredited)
- Frank Mills - Townsman (uncredited)
- Frank Mills - Trial Spectator (uncredited)
- Frank Mills - Prisoner (uncredited)
- Frank Mills - Juror (uncredited)
- Frank Mills - Sparky the Bartender (uncredited)
- Frank Mills - Frankie the Bartender (uncredited)
- Frank Mills - Cowboy (uncredited)
- Carleton Young - Skulky Grogan (uncredited)
- Carleton Young - Snakey Gratton
- Carleton Young - Denver Jones
- Carleton Young - Denver Jones (uncredited)
- Carleton Young - Judge Smith
- Rudy Doucette - Barfly (uncredited)
- John Anderson - Virgil Earp
- Bob Sweeney - Printer (uncredited)
- Don Diamond - Stevens - Suspect (uncredited)
- Jacqueline Scott - Beth Grover
- Willard Sage - Bill Casey
- Stuart Randall - Hoss Dagget (uncredited)
- Stuart Randall - Rufe Prentice
- Stuart Randall - Milt Canyon
- Paul Bryar - Reb Thomas
- Paul Bryar - Sheriff Todd
- Ralph Sanford - Mayor Jim Kelley
- Ralph Sanford - Mayor Jim Kelley (uncredited)
- Ralph Sanford - Slip Madigan
- Ralph Sanford - Butch McGuire
- Ralph Sanford - Bartender Larsen
- Ralph Sanford - Fireman Whitty
- Richard Reeves - Cowboy (uncredited)
- Richard Reeves - Bucko
- Richard Reeves - Six-Mule Marcy
- Art Dillard - Gang Member (uncredited)
- Art Dillard - Townsman (uncredited)
- Art Dillard - Big T Man (uncredited)
- Art Dillard - Cowhand (uncredited)
- John Doucette - Smiley Dunlap
- John Doucette - Orry Taylor
- Suzanne Lloyd - Mary Turner
- Lee Farr - Claude Turner
- Hal Taggart - Clerk (uncredited)
- Terry Frost - Stage Driver (uncredited)
- Terry Frost - Attorney Benton
- Terry Frost - Jake Devers (uncredited)
- Dabbs Greer - Marshal Crawford
- Ray Bennett - Deputy (uncredited)
- Joe Dominguez - Roca (uncredited)
- Del Monroe - Pete Spence (uncredited)
- John Eldredge - Homer Blythe
- Margaret Hayes - Dora Hand
- Fred Sherman - Banker Sloan (uncredited)
- Fred Sherman - Tommy the Tailor
- Fred Sherman - Tad - Hotel Clerk (uncredited)
- Fred Sherman - Bracos Tavern Proprietor (uncredited)
- Fred Sherman - Tommy - The Tailor (uncredited)
- Frank Wilcox - Les Piersall
- Bob Woodward - Gang Member (uncredited)
- Bob Woodward - Gunman (uncredited)
- Bob Woodward - Stage Driver (uncredited)
- Bob Woodward - Muleskinner (uncredited)
- Bob Woodward - Townsman (uncredited)
- Bob Woodward - Sherman's Driver (uncredited)
- Bob Woodward - Big T Man (uncredited)
- Bob Woodward - Masterson Deputy (uncredited)
- Bob Woodward - Outlaw (uncredited)
- Robert Patten - Jim Murdock
- Grace Lee Whitney - Saloon Girl (as Ruth Whitney)
- Rand Brooks - Sheriff Del Mathey
- Robert Fuller - Hank Drew
- Herschel Graham - Townsman (uncredited)
- Herschel Graham - Bank Clerk (uncredited)
- Herschel Graham - Trial Spectator (uncredited)
- Herschel Graham - Poker Player (uncredited)
- Herschel Graham - Juror (uncredited)
- Herschel Graham - Clerk (uncredited)
- Herschel Graham - Printer (uncredited)
- Herschel Graham - Charlie (uncredited)
- Herschel Graham - Diner Patron (uncredited)
- Herschel Graham - Photographer (uncredited)
- Herschel Graham - Restaurant Patron (uncredited)
- Herschel Graham - Doctor (uncredited)
- John Vivyan - Mike de Graff
- Don C. Harvey - George Beshar
- Don C. Harvey - George Peschauer
- Don C. Harvey - Rico (uncredited)
- Don C. Harvey - Jumbo - Cattle Drive Cowboy
- Don C. Harvey - Pete Anders
- Lewis Charles - Five Spot Finley
- Tom Steele - Cowboy (uncredited)
- Tom Steele - Saloon Brawler (uncredited)
- Tom Steele - Drunk in Bar
- Tom Steele - Cowhand (uncredited)
- Tom Steele - Mr. Hailey - Beaten Gambler (uncredited)
- Tom Steele - Muleskinner (uncredited)
- John Hubbard - Tim Maxwell
- John Hubbard - Mel Doniher
- Mike Connors - Pat Smith
- Jan Shepard - Mamie Perkins
- Stacy Harris - Mayor John Clum
- Stacy Harris - Mayor Clum
- Stacy Harris - John P. Clum
- Stacy Harris - Sam Rolfe
- Stacy Harris - John P. Clum (uncredited)
- Billy Nelson - Mr. Sprague
- Billy Nelson - Chuck - Bartender (uncredited)
- Billy Nelson - Masterson Deputy (uncredited)
- Lane Bradford - Mannen Clements
- Lane Bradford - Schneider
- Lane Bradford - Dave Ritchie
- Lane Bradford - Swanee - Henchman
- Charles Sherlock - Barfly (uncredited)
- Charles Sherlock - Courtroom Spectator (uncredited)
- Darryl Hickman - Dal Royal
- Aline Towne - Jenny Durkin
- Aline Towne - Amelia Woodruff
- Frank J. Scannell - Cookie the Cook
- Frank J. Scannell - Judge Franklin (uncredited)
- Eddie Hice - Clanton Henchman (uncredited)
- Eddie Hice - Henchman (uncredited)
- Eddie Hice - Clanton Cowboy (uncredited)
- Eddie Hice - Ringo Henchman (uncredited)
- Eddie Hice - Hannegan Henchman (uncredited)
- Eddie Hice - Cowboy (uncredited)
- Eddie Hice - Outlaw (uncredited)
- Russell Custer - Association Member (uncredited)
- Fay Baker - Marie Burden
- Keith Richards - Henry Harrison Hammer
- Keith Richards - Dort - Suspect Who is Killed (uncredited)
- Keith Richards - Tex - Clanton Henchman
- Keith Richards - Slick Lonagan
- Keith Richards - Al Watrous
- Anthony Eustrel - Miles Dunbar
- Wayne Mallory - Deputy (uncredited)
- Wayne Mallory - Deputy Sullivan (uncredited)
- Wayne Mallory - Deputy Louie (uncredited)
- Wayne Mallory - Cowhand (uncredited)
- Paul E. Burns - Dooley Dolan (uncredited)
- Tom London - Jigger (uncredited)
- Tom London - Old Man Craig (uncredited)
- Tom London - Stableman (uncredited)
- G. Pat Collins - Bartender (uncredited)
- John Gallaudet - John Thacker
- Dan Riss - Shelby (uncredited)
- Gregory Walcott - Odie Hewitt
- Wesley Lau - Dave Dray
- Robert Sampson - Cully Dray
- Nina Shipman - Leone Simpson
- Ann Robinson - Hetty Doane
- Bartlett Robinson - Paul Scott
- William Challee - Witness (uncredited)
- Dub Taylor - Hogan
- Eddie Kane - Bartender (uncredited)
- Eddie Kane - Mayor Randall
- Eddie Kane - Mr. Brice - Bartender (uncredited)
- Eddie Kane - Councilman Prentice (uncredited)
- Norman Leavitt - Phillips (uncredited)
- Louise Fletcher - Aithra McLowery
- Roy Engel - Zack Herrick
- Ron Foster - Johnny-Benind-the-Deuce
- Richard Benedict - Briscoe
- Peter Mamakos - Gus Cassen
- Peter Mamakos - Clay Bronson
- Peter Mamakos - Cy Johnson
- Michael Hinn - Van Horn
- Jimmy Lydon - Tom Fitch (uncredited)
- Harold J. Stone - Hiram Grant
- Lou Krugman - Frenchy - Clanton Henchman
- Lou Krugman - Dan Searls
- Gilman Rankin - Townsman (uncredited)
- Jean Allison - Minna Marlin
- Mauritz Hugo - Tom Elleridge
- Mauritz Hugo - Bud Creel
- Mauritz Hugo - Zinner
- John Craven - Harry Drew / Dolan
- Joe Turkel - Bob Rellance
- Susan Seaforth Hayes - Annie May Hamble
- Lester Dorr - Hotel Clerk (uncredited)
- Lester Dorr - Tony (uncredited)
- Lester Dorr - Hotel Clerk - Emmett
- Lester Dorr - Charlie the Hotel Clerk (uncredited)
- Lester Dorr - Mose
- Lester Dorr - Sam - Hotel Clerk
- Lester Dorr - Telegrapher (uncredited)
- Rory Mallinson - Henchman (uncredited)
- Rory Mallinson - Kenton (uncredited)
- Pitt Herbert - Sam Dutton
- Mae Clarke - Sally Roweday
- Herb Vigran - Bob Rakle (uncredited)
- Daniel B. Ullman
- Louis F. Edelman
Carleton Young interpreta a Snakey Gratton en la serie.
Angie Dickinson hace el papel de Ann Drew.
Hugh O'Brian interpreta a Wyatt Earp en la serie.
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