- James DuMont - Herpolsheimer's Manager
- Geraldine Singer - Dorothea Warren
- Jackie Earle Haley - Louis Howe
- Kate Mulgrew - Susan Sher
- Eliza Scanlen - Young Eleanor Roosevelt
- Clea DuVall - Tommy
- Jayme Lawson - Young Michelle Obama
- Derek Cecil - Donald Rumsfeld
- Michael Potts - Fraser Robinson
- Rhys Wakefield - Dick Cheney
- Ellen Burstyn - Sara Delano Roosevelt
- Judy Greer - Nancy Howe
- Cailee Spaeny - Anna Eleanor Roosevelt
- Michael Aronov - Rahm Emanuel
- Gloria Reuben - Valerie Jarrett
- Kristine Froseth - Young Betty Ford
- Rosalind Chao - Tina Tchen
- Lexi Underwood - Malia Obama
- Saniyya Sidney - Sasha Obama
- Bill Winkler - Secret Service Agent
- Patrice Johnson - Clara Powell
- Gavin White - Young Michael Ford
- Donna Lynne Champlin - Mel Winter
- Raphael Luce - Young James Roosevelt
- Jake Picking - Young Gerald Ford
- Brandon Fox - Radio Producer
- Jordyn McIntosh - Young Sasha Obama
- Vivien Lyra Blair - Little Eleanor Roosevelt
- Jeremy Bobb - Theodore Roosevelt
- Tordy Clark - Martha Bulloch Roosevelt
- Chuck Cooper - Martin Luther King Sr.
- Eric Esquer - Day Drinker
- Tom Galantich - Michael Riordan
- Kathleen Garrett - Laura Bush
- Chelsea Hayes - East Room Aide
- Tiffany Denise Hobbs - Amy Sherald
- Wyatt Hunt - Franklin Delano Roosevelt Jr.
- Martha King - Rumsfeld Secretary
- Darius Ledbetter - Craig Robinson
- Boris McGiver - Morley Safer
- Susan Macke Miller - Congressional Club President
- Mark Moses - George W. Bush
- Evan Parke - Secret Service Agent Allen Taylor
- Max Ragone - Elliot Roosevelt Jr.
- Michael Shenefelt - James Roosevelt
- Lancer Dean Shull - Steve Early
- Zane Stephens - Elliot Roosevelt
- Story Walker - Young Malia Obama
- Paul Wilson - Richard Nixon
- Jay D. Kacho - FDR Advisor (uncredited)
- Matt Skollar - Felix de Cassio (uncredited)
- Jamie Snowden - Christian Evans (uncredited)
- Riley Flanagan
- Viola Davis
- Jeff Gaspin
- Krystle Grandy
- Andrew Wang
- Susanne Bier
- Julius Tennon
Michelle Pfeiffer hace el papel de Betty Ford.
Gillian Anderson interpreta a Eleanor Roosevelt en la serie.
O-T Fagbenle hace el papel de Barack Obama.
Dakota Fanning interpreta a Susan Elizabeth Ford en la serie.
Lily Rabe interpreta a Lorena Hickok en la serie.
Regina Taylor hace el papel de Marian Shields Robinson.
Kiefer Sutherland hace el papel de Franklin D. Roosevelt.
Aaron Eckhart hace el papel de Gerald Ford.
Capítulo disponible en las siguientes plataformas:
