- Karen Kilgariff - Pam
- Patrick Kerr - Johnson
- David Cross - Earl
- Keene Curtis - Pastor Lindemann
- Gregory Jbara - Ron
- Amanda Bynes - Various
- Blake Clark - Jules Lambermont
- Christopher Darga - Brad
- Francesca Marie Smith - Monica
- Jenny O'Hara - Judge White
- Dave Winfield - Dave Winfield
- Brian Haley - Drew Look-alike (uncredited)
- Mike Hagerty - The Beer Guy
- Peter Krause - Tom
- Michael Taliferro - Delivery Man
- Peter Scolari - Councilman Kemp
- Ann Magnuson - Kyra Sullivan
- Jerry Van Dyke - Luther Van Damme
- Rachel Hunter - Rachel Hunter
- Phill Lewis - Mike
- Nicholas Turturro - Det. James Martinez
- Kevin Crowley - Morgan
- Hynden Walch - Amy
- Nia Vardalos - Grace Almada
- Jeff Doucette - The Police Marshall
- Mark Addy - Mark Addy
- Joseph D. Reitman - Herb
- Steve Buscemi - Mr. Marchetti
- Eugene Levy - Dr. Rider
- Anne Francis - Charlene Fifer
- Kiana Tom - Tia
- Jenica Bergere - Sharon Bridges
- Nikki Cox - Kristen Carey
- Paul Feig - Worker
- Joe Alaskey - Daffy Duck (voice)
- Mitchell Ryan - Woody
- Diane Klimaszewski - Mandy - Minnesota Twin
- Cassie Yates - Millie
- Victor Raider-Wexler - Paul Van Houten
- Adrienne Barbeau - Kim Harvey
- Alaina Reed Hall - Lois
- Aaron Lustig - Bill
- Antoinette Picatto - Patricia
- William Utay - Tom
- Susan Saint James - Lynn O'Brien
- Stanley Anderson - George Carey
- Stanley Anderson - Drew's Dad (voice)
- Marcia Mitzman Gaven - Kim
- Norm Macdonald - Simon Tate
- Graham Jarvis - Principal Zand
- Michael Milhoan - Joe Lupo
- Lisa Darr - Debbie
- John Caponera - Dexter K. Roberts
- Cork Hubbert - Jim
- Marion Ross - Beulah Carey
- Kenneth Mars - Mr. Tinsley
- Little Richard - Little Richard
- Brett Butler - Grace Kelly
- Wally Wingert - Parrot (voice)
- Dan Castellaneta - Stan
- Ed Begley Jr. - Dr. Chris Vanderkamp
- Donald Trump - Donald Trump
- Paul Barber - Paul Barber
- Dionne Warwick - Dionne Warwick
- Seth Green - The Emcee
- Tim Conway - Gus
- Barry Corbin - Chuck Fifer
- Jason Stuart - Chip
- Nan Martin - Mrs. Louder
- Paul Eiding - Jim
- Grant Shaud - Jack
- Grant Shaud - Grant Shaud (uncredited)
- Bailey Chase - Mark
- Patrick Bristow - The Salesman
- Elaine Klimaszewski - Sandy - Minnesota Twin
- Teller - Geller
- Lorenzo Music - Store Announcer (voice)
- Tim Allen - Tim Allen (uncredited)
- Caroline Lagerfelt - Mrs. Hoyt
- Jack Riley - Mr. Jones
- Flip Wilson - Flip Wilson
- Tom Bosley - Mr. Bobeck
- Howard George - Hank
- Jeremy Piven - Spence Kovak
- Bill Erwin - Mr. Bradbury
- Carol Channing - Carol Channing
- Sam Lloyd - Jack
- Steve Huison - Steve Huison
- Drake Bell - The Blues Kid
- Rachel True - Janet Clemens
- Robert Hegyes - Robert Hegyes
- Jeffrey Asch - Theodore
- Kate Walsh - Nicki Fifer
- Julie McCullough - Peaches
- Penn Jillette - Archibald Fenn
- Caroline Rhea - Bonnie
- Kelly Perine - Chuck
- Ian Gomez - Larry Almada
- Michael Landes - Blaine Bell
- Charlotte Booker - Sally
- Michael Bailey Smith - Big Guy
- Richard Paul - Burt
- Eric Roberts - Steven
- Lea DeLaria - Jewel
- Michael Winslow - Jimi Hendrix
- Patrick Cranshaw - Gerald Thompson
- Dave Allen - Lawyer
- Jamie Lee Curtis - Sioux
- Katy Selverstone - Lisa Robbins
- Bob Zany - Insult Man
- Dick Clark - Dick Clark
- Lisa Thornhill - Beth
- Mika Boorem - Sarah
- Luis Antonio Ramos - Clerk
- Charles Nelson Reilly - Mr. Hathaway
- Michael McDonald - The Parking Attendant
- Megyn Price - Waitress
- Andre Rosey Brown - The Bodyguard
- Neil Barton - The Security Guard
- James Lesure - Alan
- Hugo Speer - Hugo Speer
- Joely Fisher - Paige Clark
- Miles Marsico - Joey
- Nicole Sullivan - Diane Pulaski
- Charlie Weber - Brad
- Julie Uribe - Julie
- Tim Haldeman - Officer Barker
- Tim Haldeman - Police Officer
- Mary-Pat Green - Mary
- Mary-Pat Green - Woman
- Vylette Fagerholm - The Waitress
- Kevin Kennedy - Johnson
- Tammy Faye Bakker - Mrs. Tammy Bobeck
- Shannon Woodward - Girl in Cafeteria
- Rush Limbaugh - Rush Limbaugh
- Macka Foley - Security Guard #1
- Alonna Shaw - Woman
- Sheeri Rappaport - Anabelle
- Todd Duffey - Prom DJ
- Stephen Tobolowsky - Councilman
- Tom Poston - Roscoe Harvey
- Ed Morgan - Old Guy #1
- Amy Farrington - Bonnie, Drew's 1st Blind Date
- Julia Duffy - Lindsay Mercer
- Paxton Whitehead - Helford
- Gregory White - Ralph
- Richard Chamberlain - Maggie Wick
- Phyllis Diller - Bebe
- Jon Polito - Stansfield
- Jon Polito - The Baby (voice)
- Shirley Jones - Celia
- Kathryn Joosten - Natalie
- Kathryn Joosten - Ruth
- Fred Willard - Fred tuttle
- Lawrence Pressman - Dr. Zinneman
- French Stewart - Buddy
- Todd Stashwick - Tyler
- Sean O'Bryan - Dean
- Daniel Hagen - Interviewer
- E.J. Callahan - Ed
- Tom Kiesche - Carl, the dinosaur guy
- Fred Applegate - Phil
- Ben Murphy - Reverend henderson
- Michael Chieffo - Polling inspector
- Brent Hinkley - Frederick
- Hal Linden - Mr. Van zandt
- Adam West - Mitch
- Reichen Lehmkuhl - Lance
- Paul Collins - Professor stanton
- Richard Libertini - Grazie hofna
- Kevin McDonald - Heller
- Joe Walsh - Ed
- Joe Walsh - Joe Walsh
- John Ratzenberger - Himself
- June Lockhart - Misty Kiniski
- June Lockhart - Misty kiniski
- Bob Costas - Himself
- Kathy Griffin - Kathy
- Sean Masterson - Bob
- Skip O'Brien - Toby
- Scott Adsit - Mitch
- Jill Talley - Vicki
- Charles Dougherty - Harold
- Michael P. Byrne - Albert
- William Monaghan - Doctor
- Tracy Letts - Lomax
- Jennifer Jostyn - April
- Chip Chinery - Jerry the bowler
- Carolyn DeMirjian - Edna
- Gary Carlos Cervantes - The revolutionary
- Anna Gunn - Kelly walker
- Micky Dolenz - Mr. Metcalf
- Ajgie Kirkland - Customer #1
- Jeff Gordon - Himself
- Jack Geren - Kirby
- Marcus Folmar - Police officer
- Kevin McCorkle - Tony the bartender
- Rick Scarry - Hotel Manager
- Rick Scarry - Officer
- Wendy Worthington - Cindy
- Bruce A. Young - Simon Nicholas
- Gary Coleman - Drew's double
- Dean Stockwell - Hal
- Jimmie Walker - Lewis' stunt double
- Neil Flynn - Scott honey
- Stephen Lee - Donald
- Lacey Chabert - Grace
- Ben Stein - Heavenly guide
- Jess Harnell - Elvis performer
- Clarinda Ross - Administrator
- Jane Morris - Nora O'Dougherty
- Tom Silardi - Tom
- Judy Kain - Barbara
- Robert Torti - Jay Clemens
- Robert Torti - Nick
- Purva Bedi - Padma
- Henry Rollins - Mr. Jericho, Ass Kicker
- Kevin Pollak - Mr. Bell
- Bill Cobbs - Tony
- Danny Bonaduce - Chip
- Max Wright - Drew's stomach
- Frank Lloyd - Waiter
- Frank Lloyd - Customer
- Slash - Self
- Rick Nielsen - Self
- Roy Clark - Self
- Joey Ramone - Self
- Lisa Loeb - Self
- Dusty Hill - Self
- Dave Mustaine - Self
- Matthew Sweet - Self
- Martin Mull - Martin Mull (uncredited)
- Lauren Katz - Waitress
- Fred Stoller - Ed
- Renee Raudman - Leslie Burke
- Eric Saiet - Mark
- Andy Houts - Trekker
- Sandra Thigpen - Angie
- Marion Calvert - Mary
- Harley Zumbrum - Workman
- Doug Ballard - Prosecutor
- Bob Delegall - Dr. Singer
- Sonya Eddy - Woman
- Sonya Eddy - Sonya
- Seth Isler - Jimmy
- Roger Eschbacher - Mr. Shultz
- Lori Fetrick - Lori
- Lori Fetrick - Woman
- Cherene Snow - Bailiff
- Lisa Amsterdam - Janet
- Ernestine Mercer - Ernestine
- Tom Bailey - Maitre D'
- Heather Stephens - Woman
- Dennis Blair - Lester
- Joanie Fagan - Faith
- Mimi Cozzens - The Operator
- Todd Merrill - Customer
- George Petrie - Max Wagner
- Michael Bryan French - Mr. Newcomb
- Nancy Fish - Rita
- Lance Roberts - Security Guard
- William Newman - Hammond
- Justine Johnston - The Woman
- John C. McDonnell - Customer
- Otto Coelho - Janitor
- Slade Barnett - Billy Blankenship
- Max Grodénchik - Vincent
- Susan Isaacs - Kelly
- Ben Kronen - Mr. Fraser
- Gil Zuniga - Hector
- David L. Lander - Self
- David Drummond - The Man
- David Drummond - Mac
- Don Perry - Grandpa Bobeck
- Lynn Wanlass - Gigi Bobeck
- Monty Hoffman - A Guy
- Michael Leydon Campbell - Jerry
- Mark Benninghoffen - Trent
- Ben Slack - Santa
- Steven Kravitz - Stan
- Caitlin Dulany - Robin
- Bernie Kosar - Self
- Samantha Bennett - Olivia
- Pam Stone - Lois
- Donielle Artese - Featured
- Gregg Berger - Emcee
- Gregg Berger - Anchorman (voice)
- Daryl Keith Roach - Cop
- Ryan Holihan - Bob
- Susan Egan - Suzanne
- Susan Egan - Susan
- Denise Gentile - Jenny Wolfe
- Bonnie Hellman - Dr. Peters
- Sally Wingert - Parrot (voice)
- James M. Connor - Steve
- Matthew Mahaney - Man
- Paul Cassell - Todd
- Peter Iacangelo - Ice Cream Vendor
- Jack Hannibal - The Applicant
- Jean Sincere - The Old Lady
- Gene Weygandt - The Employer
- Keith Diamond - Greg Clemens
- Michael Alaimo - Pizza Delivery Guy
- Lisa Dinkins - DEA Officer
- Mary Gordon Murray - Judy
- Robin Middleton - Drew's Mother
- Bill Moynihan - The Clown
- Christiana Barron - Cheerleader
- Jonathan T. Floyd - Chauffeur
- Gregg Binkley - James
- Jim 'Reverend Horton Heat' Heath - The Underprivileged
- Gloria Dorson - Helen
- Tico Wells - Room Service Guy
- Judith Scarpone - Joanne
- Morgan Nagler - Mindy
- Ashley Gardner - Pinky
- Meagen Fay - Amanda
- Larry Brandenburg - Father McNabb
- Andy Umberger - Waiter
- Jonathan Emerson - Johnson
- Roger Owens - Peanut Vendor
- Susan Blommaert - Judge Oberman
- Steve Ireland - Joe Holiday
- Mercedes Colon - Bailiff
- Christina Moore - Court Reporter
- Michael Raysses - Bartender
- Michael Raysses - Joe
- Walter Addison - The Doctor
- Jill Matson - Trudy
- Tom Willett - Abe Lincoln
- Mario Roccuzzo - Jimmy
- Laura Meshell - Robin
- Shannon Frank - Bar Girl
- Debbie Munroe - Peggy Carey
- Brian Blondell - Bill Carey
- Karen Lynn Scott - Darcy
- Robert Machray - The Customer
- Melanie Good - The Tall Woman
- Joni Avery - The Woman
- Kevin Weisman - Carl
- Stefanie Kahn - Cheryl
- Pauley Perrette - Darcy
- Jonny Lang - Jonny Lang
- Wendle Josepher - Helen
- Jim O'Heir - Man in the Moon
- Jim O'Heir - The Maintenance Guy
- Jeff Lewis - Glen
- David Youse - Tom
- Kathleen M. Darcy - The Female Employee
- Danny Breen - Roy
- 'Weird Al' Yankovic - 'Weird Al' Yankovic
- Waddy Wachtel - Guitarist
- Elizabeth Payne - Kimberly
- Debbie Korkunis - Waitress
- Jana Marie Hupp - Margaret
- Brent Jasmer - Chris
- Steve Tom - Captain Miller
- ?? - Ming
- James Hong - Government Worker
- Ming Lo - McDonald's Manager
- Harrison Liu - Chinese Worker
- Shawn Pyfrom - Mark Foster
- Scott Rinker - Tommy Newman
- Louisette Geiss - Ellen
- John Edmund Parcher - Customer#1
- Jim Hanna - Customer
- Paul Lévesque - The Disciplinarian
- Jeremy Kramer - Johnson
- Diane Farr - Tracy
- Kenny Mayne - Kenny Mayne
- Lynn Swann - Lynn Swann
- Jeff Horny - Tom
- Dale Raoul - Fortune Teller (voice)
- Brandy Ledford - Model
- Gene Feldman - Patient
- John O'Brien - Rick
- Michael Buster - Tom
- Pat Lach - Alice
- Brandon de Paul - Young Drew
- Colin Mochrie - Eugene Anderson
- Jim Blanchette - The Bartender
- Richard Willgrubs - Man
- Dan Donohue - Dr. Jeff
- Christopher Shea - Waiter
- Ron Roggé - Contractor
- Debbie Lee Carrington - Doreen
- Karl T. Wright - Office Guy
- Peter MacKenzie - Arbitrator
- Peter MacKenzie - Mr. Firestein
- Regan Burns - Office Guy
- Paul Nobrega - Card Store Clerk
- Paul Nobrega - Attendant
- Paul Nobrega - Parent
- Paul Nobrega - Paul
- Gregory Sporleder - Wally
- Paul Gleason - Judge Crawford
- Patricia Belcher - Judge Holloway
- Jordan Marder - Skinhead
- Dan Tullis Jr. - Lawyer
- Bill A. Jones - Cop
- Carl Banks - Black Gang Leader
- Kevin Carr - Klansman
- Ethan Peck - Kid
- David St. James - Carpool Guy
- David St. James - Owen
- Bo Derek - Bo Derek
- Missi Pyle - Stacey
- Stan Cahill - Patrick Wells
- James Thomas Bailey - Barbershop Quartet Singer
- Michael Pollock - Barbershop Quartet Singer
- Joe Whyte - Barbershop Quartet Singer
- Paul Eric Jerome - Doctor
- Tom Towles - Detective Streible
- Tony Plana - Andrew Rodriguez
- Shashawnee Hall - Detective Patterson
- Pat Crawford Brown - Mrs. Hopkins
- Keith Neubert - Fireman
- Paul Taylor - Fireman
- Sebastian Tillinger - College Guy
- Maria Stanton - Woman
- Pierrino Mascarino - Old Man
- Wayne Brady - Wayne Brady
- Brad Sherwood - Brad Sherwood
- Laura Hall - Laura Hall
- Arturo Brachetti - Arturo Brachetti
- Steven William - The Stripper
- Rosa Blasi - Isabel
- Eddie Money - Eddie Money
- John Ingle - Father Seymour
- Terry Rhoads - Doctor
- Larry Milburn - Security Guard
- Earl Schuman - Uncle Alfred Carey
- Patience Cleveland - Kate's Grandma
- Bonita Friedericy - Sally
- Benjamin Brown - Billy
- Weston Nathanson - Kate's Grandfather
- Christian Aubert - Maitre d'
- Mark Curry - Robert Soulard
- Ken Lerner - Feinstein
- Hansford Rowe - Arthur Crawford
- Diana Maria Riva - Elena
- Charles Rahi Chun - Matt
- Richard Voigts - Board Member
- Judy Gold - Leslie
- Greg Lee - Crazy Al
- Bryan Cuprill - Frat Guy
- Patricia Place - Carol
- Ty Upshaw - Policeman
- Zack Phifer - Physician
- Claire Rankin - Wendy Matson
- Jennifer Wydra - Date
- Grace Morley - Date
- Jeb Barrows - Man in Bar
- J.P. Manoux - Malcolm
- Sean Smith - Johnson
- Seth Adkins - Pinocchio
- Thea Mann - Beth
- Bellamy Young - Bridget
- Tawny Moyer - The Realtor
- Paul Morgan Stetler - The Interviewer
- Jeremy Howard - Robert Gates
- Jason Rodriguez - Cowboy
- Anthony Skordi - Man
- Anthony Skordi - Announcer
- Bari Hochwald - Dr. Kelly
- Jay Leggett - Frank
- Richard Narita - Mr. Kamahela
- Beau Baxter - Michael
- Nick Jameson - Doctor Roberts
- Griffin Frazen - Sam
- Charles C. Stevenson Jr. - The Minister
- Charles C. Stevenson Jr. - Farmer
- Hayden Tank - Matt
- Kelle Korbel - The Homeless Woman
- Jack Esformes - Surgeon
- Robert Arce - Wilson
- Kim Delgado - Anderson
- Alice Frank - Cheerleader
- Brendan Walsh - Kid
- Donnie Eichar - Jared
- Jim Wise - Harry the Tuba
- Jim Wise - Karaoke DJ
- Shawnie Costello - Twin
- Cristina Maxwell - Waitress
- Cristina Maxwell - Julia
- Julie Costello - Twin
- Lauri Johnson - Gladys
- Ivan Allen - Nick
- Ben Ziff - Basketball Player
- Steve Howey - Student
- Tac Fitzgerald - Football Player
- Daniel Roebuck - Mr. Grayson
- Michael McShane - Ray
- John Apicella - Otis
- Mary Coleston - Woman
- Charles Esten - Chip
- Kathryn Greenwood - Kathryn
- Jay Leno - Lewis' Boss
- Reggie Currelley - Bartender
- Elea Oberon - Cashier
- Blake McIver Ewing - Wolfgang
- Jessica Sara - Sally
- Charlotte Caffey - The Go-Go's
- Belinda Carlisle - The Go-Go's
- Gina Schock - The Go-Go's
- Kathy Valentine - The Go-Go's
- Jane Wiedlin - The Go-Go's
- Jon Robert Hall - son of Drew Carrey
- Robert Clotworthy - INS Inspector
- Francis Guinan - Scoutmaster Bob
- Jeremy Lawrence - Justice of the Peace
- Michael Welch - Scout
- Jack Salvatore, Jr. - Scout
- Aloma Wright - Mrs. Taylor
- Aloma Wright - Security Officer
- Jamie Luner - Jenny
- Richard Gant - Reverend Holloway
- Arjay Smith - Richard
- Gabriel Williams - Willy
- Olivia Lee - Singer
- Tiffany Takara - Church Choir Singer
- Van Epperson - Worker
- David Malloy - Customer
- Daniel Graves - Doctor
- Marcy Goldman - Nurse
- Daniele O'Loughlin - Pregnant Woman
- Renee Ryan - Pregnant Woman
- Ariel Llinas - Orderly
- James Castle Stevens - Groom
- James Castle Stevens - Guy
- James Castle Stevens - Clerk
- James Castle Stevens - Delivery Man
- James Castle Stevens - Dannigan
- Denise Crosby - Officer Hayes
- Jaime Ray Newman - Tina
- Mark Tymchyshyn - Mr. Sweeney
- Alex Alexander - Woman Customer
- Mimi Lieber - Ms. Hager
- Susan Leslie - Joan
- Joey Nader - Kevin
- Pat Finn - George
- Pat Finn - Mr. Delaney
- Wylie Small - Marge
- David Purdham - Doctor
- Michelle Ruben - Woman
- Jamie Anderson - Woman
- John Valdetero - Captain Marvel
- Charles L. Brame - Abraham Lincoln
- Patrick Gorman - William Shakespeare
- Charlie Stewart - Little Boy
- Melanie A. Gage - Dancing Nurse
- Nicholas Hill - Karate Guy
- Denise Dowse - Doctor
- Orlando Ashley - Cloud Guy
- Tai Urban - Baby in Cloud
- Joe Keyes - Mailman
- Merrill Moore - Waitress
- Derek Anthony - Counselor
- Megan Gray - Young Woman
- Brad Blumenthal - Junkie
- Lucia Sullivan - Waitress
- Lindsay Hollister - Office Woman
- Zoë Yeoman - Woman
- Michael Francis Clarke - Man
- Chris Bonno - Young Man
- Stan Sellers - Middle-Aged Guy
- Greg Proops - Greg
- Greg Proops - Derek
- Lauren Stamile - Julie Baker
- Franc Ross - Bartender
- Bergen Williams - Smelly Mary
- Jeff Lapensee - Announcer (V.O.)
- Jeff Lapensee - Roger
- Gary Kasper - Biker
- Lackos - Biker
- Ava Fabian - Woman
- Andrew Bloch - Waiter
- Kim Fields - Kate's Double
- Meshach Taylor - Oswald's Double
- Thea Vidale - Mimi's Double
- David Nathan Schwartz - Chet
- Jake Fritz - Thomas
- Jillian Berard - Kimberly
- Bob Bouchard - Bob
- Bob Bouchard - Quintin
- Kathie Lee Gifford - Vanessa Bobeck
- Illeana Douglas - Rachel Murray
- Brandon Keener - Scott
- Harold Green - BBQ Bar Owner
- Harry Groener - Dr. Hershlag
- Dwayne Foster - Cop
- Ben Williams - Pete
- Jimmy Palumbo - Dennis
- Jim Zulevic - Earl
- Tom Pardoe - Henderson
- Benton Jennings - Bill
- David Ruprecht - Inmate
- Mary Gillis - Nurse Baylin
- Roz Witt - Fifty-Year-Old Woman
- Helen Slayton-Hughes - Eighty-Year-Old Woman
- Peter Frampton - Peter Frampton
- David Doty - Minister
- Bette Rae - Mrs Johnson
- Mike Grief - Pirate
- Helen Eigenberg - Stephanie
- Rachel Winfree - Gladys
- Lesley Fera - Judy
- Paul Johansson - Ron Higgins
- Henry Winkler - Mr. Newsome
- Charles Fleischer - Dr. Kresheck
- Jenny McCarthy-Wahlberg - Jenny McCarthy / Various
- Jenny McCarthy-Wahlberg - Marlo Kelly
- Ashlynn Rose - Little Girl
- Laura Margolis - Flashback Girl
- Gerry Cohen - Gerry Cohen
- Wanda Sykes - Christine Watson
- Lance E. Nichols - Warren
- Lillian Lehman - Elizabeth
- Dale Godboldo - Gerard
- Darius Dudley - The Reverend
- Toru Tanaka Jr. - Strongman
- Dee Snider - Self
- Rick Zieff - Salesman
- Jeff Bryan Davis - Jeff - Stall for Time Player
- Jeff Bryan Davis - D'Artagnan
- Christopher Halsted - Jeremy
- Marla Frees - Sylvia
- Max Gail - Les
- Steve Turner - Comedian
- Dulcy Rogers - Colleen
- Jim Piddock - Lord Mercer
- Mike Randleman - Mr. Starkey
- Lane Napper - Dispatcher (voice)
- Jessica Cauffiel - Milan
- Dom Irrera - Stan
- Don Tiffany - Joe
- Margaret Travolta - Mrs. Bishop
- Suzanne Sena - Suzanne Sena
- Leslie Sykes - Leslie Sykes
- Cooper Thornton - Male Passenger
- Anna Marie Goddard - Greenland Girl
- Sandra Goff - Bouncy Time Tina
- Jim Cody Williams - Ed
- Nicholas K. Gilhool - Doctor
- Richard Topol - Bob
- Jeff Michalski - 60's Stage Manager
- Jeff Michalski - Policeman
- Bridgett Newton - Kelly
- Beata Pozniak - Raisa
- Cheryl White - Heather Thompson
- Julie Pinson - Beverly
- Julie Ann Emery - Amy
- Alysia Reiner - Sally
- Tami Roman - Susan
- Nancy Linehan Charles - Judge Martin
- Rebecca Staab - Melanie
- Dana Peterson - Cyber Nanny
- Scotty Leavenworth - Danny
- Kat Sawyer-Young - Woman
- Ben Zook - Underpants Guy
- Jonathan Mangum - Scott
- Amanda Wyss - Tina
- Cameron Mathison - Kirk
- Kaitlin Olson - Traylor
- Ron Pearson - Maitre D'
- Ron Pearson - Defense Attorney
- Ron Pearson - Minister
- Ron Pearson - Ringmaster
- Paul Benedict - Jeremy
- Bashir Salahuddin - Cop
- Joe Dietl - Cop
- Dublin James Wahlberg - Rand
- Ion Overman - Stacey
- Kristin Dattilo - Amy
- Suzanne Cryer - Karen
- Jeannetta Arnette - Gloria
- A.J. Langer - Dawn
- Lori Loughlin - Robin
- Amy Christine - Gail
- Shawn Christian - Grant
- Tate Taylor - Jim
- Michael Lowry - Drake
- Brian Stepanek - Bob
- Samm Levine - Jake
- James Denton - Daryl
- Roselyn Sánchez - Maria
- James Martin Kelly - Liquor Store Manager
- Markus Redmond - Delivery Guy
- Gary Sievers - Dirty Man in Liquor Store
- David Earl Waterman - Jack
- Noa Tishby - Rachel
- Sybil Azur - The Actress
- Denise Faye - Susie
- Lara Phillips - Lacy
- Tim Beggy - Waiter
- Tim Conlon - Peter
- Tim Conlon - Prosecuting Attorney
- Emma Hunton - Madison
- Chase Winton - Phyllis
- Tami Tappan Damiano - Woman
- Amy Pietz - Elaine
- Melanie Paxson - Teri
- Richard Wharton - Gerald
- Richard Wharton - Construction Worker
- Geoff Pierson - Ted
- Molly Bryant - Tina
- Sarah Scott Davis - Woman
- Jeff Ricketts - Bum
- Bryna Weiss - Alice
- Robyn Lively - Erin
- Virginia Hamilton - Nurse
- Susan Beaubian - Nurse Perry
- Shelley Pack - Trainer
- Cynthia Lamontagne - Dr. Casey Newell
- Tammy Lauren - Lily
- Iris Bahr - Mindy
- Jodi Harris - Debbie
- Jan Devereaux - Mrs. Crawford
- Gillian Shure - Amber
- Larry Marko - Old Guy
- Matthew Josten - Gus
- Scott Klace - Mr. Murphy
- Dennis Bailey - Dr. Melnick
- Diora Baird - Valerie
- Hyla Matthews - Anna
- Susan Sullivan - Annette Newmark
- Michael Gross - Don Newmark - Kellie's Father
- Tim Maculan - Mr. Warwick
- Susan Mackin - Jana
- Timothy Davis-Reed - Father
- Roxanne Day - Kristy
- Julie Pop - Mona
- Jacqueline Schultz - Pam
- Barry Livingston - Mr. Walters
- Bonnie McFarlane - Sara
- Victoria Profeta - Patty
- Kristen Wiig - Sandy
- Steve Sheridan - Fred
- Lawrence H. Toffler - Customer
- Lindsey Stoddart - Marla
- Edward Padilla - 3D Baby (voice)
- Iyari Limon - Carmelita
- Jack Guzman - Joe
- Currie Graham - Russell
- Ernie Lively - Mike
- Frankie J. Allison - Nick
- Tim Lucason - Firefighter
- Wayne Knight - Owen
- Carol Ann Susi - Doris
- Maria Ford - Crystal / Nancy, the Stripper
- Sirena Irwin - Raven
- J. Patrick McCormack - Jonathan
- Colleen Flynn - Lorna
- Millicent Martin - Helen
- Eliza Coyle - Nurse
- Holmes Osborne - Priest
- Dennis Burkley - Biker #3 (uncredited)
- Lemmy Kilmister - Self
- Phil Campbell - Self
- David Letterman
- Russ Woody
- Drew Carey
- Clay Graham
- Bruce Rasmussen
- Richard Day
Stephen Tobolowsky hace el papel de Councilman.
David St. James hace el papel de Carpool Guy.
Kathy Griffin interpreta a Kathy en la serie.
John Carroll Lynch interpreta a Steve Carey en la serie.
Bruce A. Young hace el papel de Simon Nicholas.
Steve Buscemi interpreta a Mr. Marchetti en la serie.
Jenny O'Hara interpreta a Judge White en la serie.
Drew Carey interpreta a Drew Carey en la serie.
Joely Fisher interpreta a Paige Clark en la serie.
Dean Stockwell hace el papel de Hal.
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