- Shelley Fabares - Mary Stone
- Carl Betz - Dr. Alex Stone
- Johnny Crawford - Victor
- Ellen Corby - Christine Moss
- Jimmy Hawkins - Scotty
- Gigi Perreau - Cathy Robinson
- John Fiedler - Fred Johnson
- Lee Aaker - Kenny
- Cecil Kellaway - Algerion O'Hara
- Harvey Korman - Carter Melville
- Raymond Hatton - Mr. Barnhill
- George Hamilton - Herbie Shields
- Margie Liszt - Vera Platt
- Roberta Shore - Carol
- Maudie Prickett - Miss Sanders
- Bob Crane - Dr. Dave Kelsey
- Harold Gould - Cal Winslow
- Tommy Ivo - Herbie
- Mary Shipp - Lydia Langley
- Milton Frome - Desk Sergeant
- Irving Bacon - Mayor Webster
- Dick Wilson - Mr. Carothers
- William Corcoran - Gregg Williams
- Paul Engle - Spike
- Paul Engle - Zachary
- Pat Close - Butch
- Larry Merrill - Cliff
- Kevin O'Neal - First Boy
- Herbert Lytton - Mr. Cooper
- Natalie Masters - Miss Aldridge
- Melinda Byron - Betsy
- Florence MacMichael - Madeline Richards
- Sam Flint - Dr. Wiggins
- Sid Tomack - Mac
- Don C. Harvey - Dr. Harry Marcy
- Frances Robinson - Myra
- Frances Robinson - Ellen Marcy
- Keith Richards - Dr. Lester Brock
- Robert Shayne - Dr. Flanigan
- Mario Siletti - Waiter
- Tom McKee - Counterman
- Richard Reeves - Construction Worker
- Robert Ellis - Young Man
- Richard Gaines - Dr. Elias Spaulding
- Raymond Bailey - George Collier
- Irene Hervey - Louise Collier
- Mary Carver - Miss Robbins
- Jacques Scott - Pierre
- Ann Morriss - Fran
- Doreen Lang - Miss Ferguson
- Frank Wilcox - Bartley Langley
- J. Edward McKinley - Dr. Peabody
- Melinda Casey - Sue
- Fred Kruger - George Platt
- Bobby Clark - Gordie
- Gladys Hurlbut - Aunt Belle
- Will Wright - Oliver
- Bill Zuckert - Jason Farnum
- Kristine Miller - Betty Murdock
- Kristine Miller - Edna
- Barbara Perry - Buffie
- Fay Baker - Hope
- Herschel Graham - Reunion Guest (uncredited)
- Herschel Graham - Pedestrian (uncredited)
- Ann McCrea - Midge Kelsey
- Virginia Christine - Margaret Lang
- Anne Whitfield - Helen Cooper
- Jay Strong - Stan
- Suzi Carnell - Betty Smith
- Rickie Sorensen - Bobby Cole
- Mary Treen - Mrs. Larson
- Mary Treen - Miss Winters
- Mary Treen - Sunny Cooper
- Dabney Coleman - Rallye Master
- Michael Vandever - Matthew Morgan
- George Cisar - Baxter
- Jay North - Dennis Mitchell
- Joseph Kearns - George Wilson
- Constance Moore - Doris
- Jerry Hausner - Jerry Parker
- Elaine Riley - Dorothy Burns
- James Darren - Buzz Berry
- James Darren - Kip Dennis / Jim Bryce
- Ted Knight - Phil Martin
- Paul Bryar - Huckster
Doreen Lang interpreta a Miss Ferguson en la serie.
George Hamilton interpreta a Herbie Shields en la serie.
Paul Petersen interpreta a Jeff Stone en la serie.
Donna Reed interpreta a Donna Stone en la serie.
Carl Betz interpreta a Dr. Alex Stone en la serie.
Capítulo disponible en las siguientes plataformas:
