- Josh Groban - Danny Chase
- Joshua Gomez - George
- Sarah Baker - Jean
- J.D. Walsh - Randall
- Adriana Lima - Adriana Lima
- Marcus Henderson - Teddy
- Kelly Clarkson - Kelly Clarkson
- Gail O'Grady - Hannah Sharples
- Mark L. Taylor - Ted
- Brent Jennings - Kyle
- Nicole Randall Johnson - Debbie
- Ashley Dyke - Pretty Girl
- Chasty Ballesteros - Carly the Model
- Philip V. Bruenn - Todd the Model
- Gabriela Fresquez - TV Reporter
- Kelly Bellini - Woman
- Tim Mikulecky - Man
- John Marshall Jones - Mitch
- Rod McLachlan - Terrance
- Todd Robert Anderson - Father
- Jen Lilley - Claire
- Tom Ayers - Guy
- Dana L. Wilson - Woman
- Teala Dunn - Taylor
- Rodney J. Hobbs - Man
- Courtney Taylor Burness - Daughter
- Michelle LaRue - Natalie
- J. Kristopher - Firefighter
- Saffron Burrows - Helena
- Fred Melamed - Fred Melamed
- Hugo Armstrong - Carl
- Michael Landes - Josh Hayes
- Alan Rachins - Bud Lymsky
- Abraham Lim - Mike
- Mary Wickliffe - Judy
- Brandon Gibson - Waiter
- Ron Bottitta - Eddie
- Jonno Roberts - Grant
- Michelle Arenal - Cute Girl
- Shane Brady - Band Mate
- Ari Stidham - Ari
- Ari Stidham - Crowd Member
- Brad Garrett - Gordon Lewis
- Barry Shabaka Henley - Pete
- Ed Asner - Mr. Finger
- Daisy Aitkens - Maid
- Christine Garver - Katie
- Eric Normington - Male Customer
- Asante Jones - Bill
- Brooke Lyons - Nancy
- Andre Ing - Medic
- E.J. Callahan - Janitor
- Laura Hunter Drago - Scared Employee
- Lavell Crawford - Marvin
- Lex Medlin - Harold
- Lance Barber - Clyde
- P.J. Ochlan - Maitre D
- Ashley Tisdale - Kelsi Lasker
- Jim Holmes - Martin Lasker
- Brian Stepanek - Phil
- John O'Brien - Larry
- Brenda Koo - Brooke
- Teddy Lane Jr. - Security Guard
- Lenny Jacobson - Jerome
- Steven Boyer - Squirrel
- Thomas Fowler - Desmond
- Zylan Brooks - Zen-Phoria Exec
- Larry Sullivan - Garrett
- Judith Moreland - Sandra
- Brennan Elliott - Kyle
- Morgan Bastin - Lily
- Helen Hong - Jenny
- Stephanie Faracy - Judy
- Sandeep Parikh - Colin
- John Eric Bentley - Cop
- Jazzmun - Anastasia
- Daniel Bess - Dylan
- John Duerler - Security Guard
- Eric Zuckerman - Security Guard
- Lauren Bulloch - Tea Employee
- Missi Pyle - Melora
- Kurt Fuller - Mitchell Payson
- Kelly Perine - Calvin
- Cheryl Hines - Beth Minker
- Steve Talley - Owen
- Jackie Seiden - Zoe Gold
- Joe West - Noah Minker
- Norma Michaels - Aunt Sadie
- Tia Robinson - Pepper
- Alexis Brandt - Pepper
- Christopher Carley - Peter
- Pramod Kumar - Jaleel
- Kareem Abdul-Jabbar - Kareem Abdul-Jabbar
- Jamie Denbo - Katherine
- Jessica Chaffin - Elaine
- Carmella Riley - Molly
- Scott Klace - Roger
- Stephanie Cannon - Eileen
- Lauren Pritchard - Ellen
- Anna Vocino - Helen
- Dana De La Garza - Actress
- Joe Nuñez - Blaine
- Tiya Sircar - Allie
- Jane Edith Wilson - Millie
- Lisa K. Wyatt - Jane
- Brad Paisley - Brad Paisley
- Baldeep Singh - Doctor
- David Copperfield - David Copperfield
- Jonathan Del Arco - Timothy
- Jennifer Marsala - Anna
- Ben Begley - Neal
- Pam Dawber - Lily
- Jeff Holman - Announcer
- Melody Thomas Scott - Flora
- Gayle King - Gayle King
- Ukee Washington - Reporter
- Ivy George - Little Girl
- Corey Mendell Parker - Trevor
- Jill Johnson - Amy
- Gillian Alexy - Megan
- Marilu Henner - Paige
Robin Williams hace el papel de Simon Roberts.
Sarah Michelle Gellar hace el papel de Sydney Roberts.
James Wolk interpreta a Zach Cropper en la serie.
Hamish Linklater interpreta a Andrew en la serie.
Amanda Setton hace el papel de Lauren Slotsky.
Capítulo disponible en las siguientes plataformas:
