- Gene Roddenberry - Self (archive footage)
- Nat Segaloff - Self
- Ralph Senensky - Self
- Harlan Ellison - Self (archive footage)
- Bob Kline - Self
- Fred Bronson - Self
- Bill Reed - Self
- Preston Neal Jones - Self
- David Gautreaux - Self
- Marc Cushman - Self
- Harold Livingston - Self
- Harve Bennett - Self (archive footage)
- Denise Crosby - Self
- Wendy Neuss - Self
- David Carson - Self
- Lolita Fatjo - Self
- Jeri Taylor - Self
- Kate Mulgrew - Self
- Ethan Phillips - Self
- David Livingston - Self
- David Gerrold - Self
- Larry Nemecek - Self
- Tim Russ - Self
- John Dykstra - Self
- Robert Sallin - Self
- Ken Ralston - Self
- Rick Berman - Self
- Herman F. Zimmerman - Self
- Manny Coto - Self
- Mark A. Altman - Self
- Leonard Nimoy - Self (archive footage)
- Joseph D'Agosta - Self
- Nichelle Nichols - Self
- Walter Koenig - Self
- Ronald D. Moore - Self
- Denise Okuda - Self
- Michael Okuda - Self
- Doug Drexler - Self
- Merri D. Howard - Self
- Rick Worthy - Self
- Sarah Silverman - Self
- Kirstie Alley - Self
- Michael Dorn - Self
- Jeri Ryan - Self
- Robert Beltran - Self
- Dominic Keating - Self
- Ron Surma - Self
- Vaughn Armstrong - Self
- Jonathan Frakes - Self
- Johanna Watts - Self
- Nicole de Boer - Self
- Terrell Tilford - Self
- Wade Williams - Self
- Ike Eisenmann - Self
- Cirroc Lofton - Self
- Anthony Montgomery - Self
- Scott McDonald - Self
- D.C. Fontana - Self (archive footage)
- Andrew Robinson - Self
- John Billingsley - Self
- James Cromwell - Self
- Chase Masterson - Self
- Penny Johnson Jerald - Self
- Roxann Dawson - Self
- Spencer Garrett - Self
- Whoopi Goldberg - Self
- Wil Wheaton - Self
- Catherine Hicks - Self
- Christopher Lloyd - Self
- Connor Trinneer - Self
- Robert Picardo - Self
- Josette DiCarlo - Self
- Barbara Williams - Self
- Cristine Rose - Self
- Matt Malloy - Self
- Armin Shimerman - Self
- Brent Spiner - Self
- Robin Curtis - Self
- Michael Westmore - Self
- William Morgan Sheppard - Self
- Sandra Lee Gimpel - Self
- Nana Visitor - Self
- Alicia Coppola - Self
- Gregory Itzin - Self
- Peter White - Self
- Jack Kehler - Self
- Mel Winkler - Self
- Rainn Wilson - Self
- John de Lancie - Self
- Brannon Braga - Self
- Ronny Cox - Self
- André Bormanis - Self
- Mark Rolston - Self
- Richard Herd - Self
- Matt McCoy - Self
- Nicholas Meyer - Self
- Robert Blackman - Self
- Diana Muldaur - Self
- Gates McFadden
- Brian Volk-Weiss
- Cisco Henson
Kirstie Alley hace el papel de Self.
Ronny Cox interpreta a Self en la serie.
Christopher Lloyd interpreta a Self en la serie.
Jonathan Frakes interpreta a Self en la serie.
Michael Dorn interpreta a Self en la serie.
Gates McFadden interpreta a Self / Narrator en la serie.
Whoopi Goldberg interpreta a Self en la serie.
James Cromwell interpreta a Self en la serie.
Denise Crosby interpreta a Self en la serie.
Leonard Nimoy interpreta a Self (archive footage) en la serie.
Capítulo disponible en las siguientes plataformas:
