- Vic Morrow - Leroy Benson
- William Fawcett - Homer Stilson
- Duncan McLeod - Zales
- Shepperd Strudwick - Bill Mowry
- Jack Mullaney - Jed Krieger
- Walter Coy - Dr. John F. Steele
- Mary Jackson - Mrs. Krieger
- Yvonne Craig - Susan Mowry
- Ralph Bellamy - Dobson
- Judy Dan - Miss Kow
- Layne Tom Jr. - Cantonese Clerk
- Beulah Quo - Amah
- Charles Bickford - Isaiah B. Richardson
- Gerald Mohr - Charlie Cahill
- David Kent - Jared Cahill
- Jamie Forster - Judge Withers
- Roy Engel - Colby
- Nesdon Booth - Ticket Agent
- Gene Coogan - Handy
- Warren Vanders - Cowhand
- Brent Sargent - Dr. Michael Talbot
- Wilton Graff - Dr. Alvin Lesley
- Yvette Vickers - Peggy
- Julie London - Julie
- Michael Ansara - Carl
- Robert Paige - Roger
- Robert Strauss - Herbie
- Joe De Santis - Paul
- Naomi Stevens - Miss Pearl
- Linda Henrich - Doris
- Claire Griswold - Ellen
- Milton Berle - Charlie
- Katherine Squire - Elvie
- Lurene Tuttle - Tessie
- Virginia Vincent - Dulcy
- Anna May Wong - A-Hsing
- J. Pat O'Malley - Steve Connors
- Russell Arms - James Horn
- Arthur Gould-Porter - Sir Cedric Carstairs
- George Givot - Nick Patros
- James Hong - Sam Wong
- Weaver Levy - Charley
- Philip Ahn - Lee Chin
- Harold Innocent - Binky Carstairs
- Victor Sen Yung - Dr. Wing Chin-Ni
- Guy Lee - Bartender
- Clarence Lung - Po
- Ellen Drew - Kate
- Henry Hunter - Manager
- Geraldine Wall - Nurse
- Michael Rennie - Julius
- Gene Raymond - Phil
- Frank Overton - Roy
- Elizabeth Patterson - Mrs. Melvane
- Amanda Randolph - Cora
- Lee Marvin - Jud Hollister
- Josephine Hutchinson - Betty Galloway
- Penny Santon - Mrs. Donnatti
- Kenneth MacKenna - Morgan
- Jerome Thor - Pete Bishop
- Richard Eastham - Sam Verner
- Robert Armstrong - Insp. Gunnison
- Jack Mather - Capt. Bragan
- Morris Ankrum - Walter Harwood
- Karl Held - Det. Jones
- Eduard Franz - Dr. Paul Aldrich
- Mike Keene - Walter Harrison
- Barbara Stanwyck - Self - Host
- Barbara Stanwyck - Josephine Little
- Barbara Stanwyck - Carolyn Callendar
- Barbara Stanwyck - Chris Mathews
- Barbara Stanwyck - Hazel Wexley
- Barbara Stanwyck - Harriet Melvane
- Barbara Stanwyck - Sister Thomas Aquinas
- Barbara Stanwyck - Amelia Lambert
- Barbara Stanwyck - Marian Andres
- Barbara Stanwyck - Dr. Susan Bryce
- Barbara Stanwyck - Paula Manning
- Barbara Stanwyck - Rachel Harrison
- Barbara Stanwyck - Maggie McClay
- Barbara Stanwyck - Janet Jones
- Barbara Stanwyck - Cara Lester
- Barbara Stanwyck - Stella King
- Barbara Stanwyck - Elizabeth Mowry
- Barbara Stanwyck - Avis Fleming
- Barbara Stanwyck - Alicia
- Barbara Stanwyck - Fanny Evans
- Barbara Stanwyck - Madge Terry
- Barbara Stanwyck - Liz Randall
- Barbara Stanwyck - Nellie Bly
- Barbara Stanwyck - Louise Forest
- Barbara Stanwyck - Margot LaChelle
- Barbara Stanwyck - Amanda Prescott
- Barbara Stanwyck - Syd Charing
- Barbara Stanwyck - Trixie Callahan
- Barbara Stanwyck - Maggie Wenley
- Barbara Stanwyck - Ella Cahill
- Barbara Stanwyck - Fran Elick
- Ross Elliott - Col. Hawthorne
- Jay Adler - Waxman
- Donald Buka - Maj. Smith
- Manning Ross - Mike
- Ray Walker - Policeman
- Carol Nicholson - Shirley Harrison
- Kent Smith - Dexter Willis
- John McGiver - Collins
- Robert Emhardt - Ben
- James Chandler - Sgt. Gibbs
- James Chandler - Lieutenant
- Jason Robards Sr. - Rupert Willis
- Almira Sessions - Cassie
- Paul Barselou - Fred Blakeley
- Lew Ayres - Dr. Paul Harris
- Robert Culp - Archie Bishop
- Nora Marlowe - Moll Seabright
- Richard Hale - Gibson Hunsucker
- Harry Jackson - Hops Tobey
- Nestor Paiva - Joe
- Murray Alper - Buck
- David Balfour - Andy
- Tony Maxwell - Davey Elick
- Dan Duryea - Pierre
- Robert Horton - Horace
- Joan Blondell - Helene Terry
- James Best - Joe
- Helene Hatch - Elsie
- Jimmy Lydon - Harry
- George D. Wallace - Johnson
- Charles Anthony Hughes - Guard
- Wallace Ford - Harry
- Harold J. Stone - Jake Lytell
- Rex Holman - Cutty
- Frank Leo - Mangione
- Jackie Searl - Rascoe
- Wallace Rooney - Capt. Foyle
- Lee Frederick - Det. Barnes
- Eloise Hardt - Blonde
- Dana Andrews - Clint Evans
- Alex Montoya - First Bandido
- Pepe Hern - Second Bandido
- Buddy Ebsen - Dr. Mark Carroll
- Judy Strangis - Little Big Mouth
- Abel Fernandez - Tom Tall Bear
- Lane Bradford - Wiley Haskell
- Leon Ames - Damon Carlisle
- Roberto Contreras - Joe Jack Rabbit
- Peter Falk - Joe
- Julia Montoya - Mrs. Two Babies
- Dub Taylor - George B. Glines
- Joseph Cotten - Mac McClay
- Elana Eden - Anna
- Addison Richards - James Fitzgibbon
- Celia Lovsky - Frau Schilling
- Ben Wright - Dr. Bradnar Lee
- John Gallaudet - Judge Simon
- Amy Douglass - Theresa Freeland
- Lawrence Tierney - Detective
- Andy Devine - Det. Sgt. 'Big' Jake Sloan
- Charles Drake - Ben Stockton
- Edgar Buchanan - Judge Franklin
- Clinton Sundberg - Billy Devers
- Sam Buffington - Vic Trenton
- Jason Johnson - Gus Gavin
- Andy Albin - Red Quincy
- William Benedict - Joe
- Carl Crow - Cowhand
- Nacho Galindo - Bartender
- Stephen McNally - Bill
- Tenen Holtz - Bronsky
- Jack Nicholson - Bud
- Hume Cronyn - Charles King
- Michael Vandever - Teenager
- Virginia Gregg - Vivian Lambert
- Patric Knowles - Simon Lambert
- Glenn Langan - Frank Morrow
- Sarah Selby - Mary McShane
- Lloyd Nolan - George McShane
- Stuffy Singer - Joe McShane
- John Kellogg - Jim
- Marion Ross - Dottie Moll
- June Vincent - Helen Gates
- Alan Hewitt - Jack Harrison
- Dennis Hopper - Gerald Collins
- Susan Oliver - Tracy Lane
- Rafael Campos - Alfredo Susarrey
- Charles Quinlivan - Det. Thomas Kelly
- Denise Alexander - Janue Hunter
- Ruth Brady - Marie
- Peggy Cass - Nurse Annie Bergner
- Stewart Bradley - Mungo McGrath
- James Philbrook - Jim Costain
- John Wilder - Joe
- Louis F. Edelman
- William H. Wright
- Earle Hagen
Naomi Stevens hace el papel de Miss Pearl.
Jack Nicholson interpreta a Bud en la serie.
Peter Falk hace el papel de Joe.
Jay Adler hace el papel de Waxman.
Josephine Hutchinson interpreta a Betty Galloway en la serie.
Buddy Ebsen hace el papel de Dr. Mark Carroll.
John McGiver interpreta a Collins en la serie.
Robert Armstrong hace el papel de Insp. Gunnison.
Ralph Bellamy hace el papel de Dobson.
Lew Ayres interpreta a Dr. Paul Harris en la serie.
Capítulo disponible en las siguientes plataformas:
