- Melissa Joan Hart - Sabrina Spellman
- Nick Bakay - Salem Saberhagen (voice)
- John Castellanos - Capablanca
- Jill Ritchie - Cheerleader
- Marcia Wallace - Angela
- Anastasia Horne - Edie
- Ken Magee - Mr. Joblonski
- Wendy Phillips - Lisa Jansen
- Isabel Sanford - Laurie
- Nick Jameson - Announcer (voice)
- Aaron Lohr - Kyle
- Kevin Michael Richardson - Coach Fortner
- Christian Malmin - Rudolph Valentino
- Dee Snider - Sammy Noah
- Brent Jasmer - Bob
- Mick Cain - Sweater Guy
- Mick Cain - Derek
- Zachery Ty Bryan - Zachery Ty Bryan
- Sarah Freeman - Shawn Puffy Clouds
- David Graf - Lenny
- Robert Costanzo - Uncle Lou
- Laurie Franks - Grandma Moses
- Shari Albert - Diane
- Ami Dolenz - Cindi
- Adam Kaiz - Kenny
- Steve Susskind - Town Crier
- Gary Bullock - Abraham Lincoln
- Bridget Flanery - Jessica
- Mark Metcalf - Mr. Nitkze
- Mark Metcalf - Mr. Nitzke
- Maurice LaMarche - TV Announcer (voice)
- Maurice LaMarche - Talking Skull / Commercial Announcer (voice)
- Maurice LaMarche - Stadium Announcer / Radio Announcer (voice)
- Maurice LaMarche - Film Narrator (voice)
- Maurice LaMarche - Radio DJ (voice)
- Maurice LaMarche - Principal Crawford / Newscaster (voice)
- Maurice LaMarche - Principal Crawford (voice)
- Maurice LaMarche - Planetarium Announcer (voice)
- Maurice LaMarche - Teddy Bear (voice)
- Tommy Hinkley - Casey Beauchamp
- Stuart Weiss - Albert EInstein
- Tim Curry - Frog (voice)
- Yeardley Smith - Miss Gross
- Jerry Van Dyke - Jerry Beauchamp
- Rory Knox Johnston - Cumberton
- Daniel 'Smalls' Johnson - Bouncer
- Thom Sharp - Dr. Handy
- Brian Poth - Alternate Steve
- Beverly Garland - Grandma
- Steven Barr - Terry
- Irene Ng - Nia
- Steve Baldikoski
- Bryan Behar
- Michael Price
- Bill Freiberger
- Al Jean
- Mike Reiss
- Lisa London
- Bob Bendetson
- Larry Wilmore
Mike Damus hace el papel de Marty DePolo.
Corbin Allred interpreta a Steve Beauchamp en la serie.
Jordan Brower interpreta a Jordan Lubell en la serie.
Conchata Ferrell interpreta a Aunt Pam en la serie.
Katie Volding hace el papel de Katie Beauchamp.
Maureen McCormick interpreta a Judy Beauchamp en la serie.
Ron Glass hace el papel de Rod.
Capítulo disponible en las siguientes plataformas:
