- Sam Jackson - Alex Henley
- Sebastian de Souza - Matty Levan
- Laya Lewis - Liv Malone
- Jessica Sula - Grace Blood
- Sean Teale - Nick Levan
- Kaya Scodelario - Effy Stonem
- Kathryn Prescott - Emily Fitch
- Lily Loveless - Naomi Campbell
- Lisa Backwell - Pandora Moon
- Luke Pasqualino - Freddie McClair
- Jack O'Connell - James Cook
- Red Madrell - Amanda
- Ardal O'Hanlon - Kieran
- Nina Wadia - Anwar's Mum
- Maureen Lipman - Aunt Elizabeth
- Dorian Lough - Leon Levan
- Kelly Brook - Jemima
- Mark Monero - Ronnie Fazer
- Maurice Roëves - Alex
- Daniel Ryan - Kevin Hardbeck
- Mark Heap - Graham
- Pauline Quirke - DS Blunt
- Charlie Creed-Miles - Fighting Bath Man
- Olga Fedori - Anka
- Sean Pertwee - Soldier on the Train / Simon the Lecturer
- Ingrid Lacey - Catherine Creevey
- John Sessions - Geoff Fitzgerald
- Jaye Griffiths - Agnes Malone
- Ronni Ancona - Jenna
- Mackenzie Crook - John White
- Toby Longworth - Bryan
- Mariah Gale - Polly
- Arabella Weir - Anna
- Josie Lawrence - Liz
- Geoffrey Hughes - Uncle Keith
- Michael Hodgson - Donald
- Simon Day - Leo Mclair
- Shane Richie - Bruce
- Morwenna Banks - Anthea Stonem
- Joann Condon - Ginny
- Alistair McGowan - Coach Pooter
- Chris Addison - David Blood
- Steve Furst - Stanley
- Kevin Eldon - Manfred
- John Thomson - Sam Brooks
- Siwan Morris - Angie
- John Bishop - Rob
- Danny Dyer - Malcolm
- Klariza Clayton - Karen Mclair
- Joe Prospero - Emo Kid 1
- Olivia Colman - Gina
- Dorothy Atkinson - Receptionist
- Sara Crowe - Hair & Beauty Teacher
- Sarah Lancashire - Mary
- Dave Hill - Dewi
- Sia Berkeley - Scarlett
- Clare Grogan - Shelley McGuinness
- Tom Payne - Spencer
- Harry Enfield - Jim Stonem
- James Buckley - Simon
- Inder Manocha - Istiak
- Victoria Wicks - College Director
- Rupert Holliday-Evans - Priest
- Fiona Allen - Jackie
- John Weldon - Kenny - Big Issue Seller
- David Baddiel - Steve
- Georgina Moffat - Abigail
- Iddo Goldberg - William
- Bill Bailey - Walter
- James Fleet - Martin
- Pooky Quesnel - Claire
- Michael Nardone - Sandy
- Peter Capaldi - Mark
- Ben Lloyd-Hughes - Josh
- Giles Thomas - Doug
- Sally Phillips - Angela
- Stephen Walters - Mad Twatter
- Daniel Kaluuya - Posh Kenneth
- Troy Glasgow - Ace
- Robert Wilfort - Tom
- Esther Smith - Emma
- Lucien Laviscount - Jason
- Liam Boyle - Louie
- Hannah Britland - Charlie
- Jamie Michie - Rob
- Duncan Duff - Congratulations Leader
- Matt Kane - Emo Kid 2
- Craig Roberts - Dominic
- Maxim Baldry - Banjo
- Joe Cole - Luke
- Spencer Jones - Doctor Proctor
- Chris Ashby - Steve
- Manjinder Virk - Doctor Berg
- Josie Long - Josie
- Javine Hylton - Precious
- Thaila Zucchi - Cheryl
- Scott Mills - Presenter
- Rich Fulcher - Judge Jordan
- Orion Ben - Navah
- Marcia Bennett - Irene Polaski
- Amir Boutrous - Hagai
- Richard Crehan - Johnny
- Shimi Goodman - Roi
- Ashley Horne - Stephen
- Robert Pearce - Ruben Ainsworth
- James Patrick - Charlie
- Alexia Traverse-Healy - Marlene
- Tara Wells - Marsha
- Daniel Ben Zenou - Yaniv
- Olly Alexander - Jakob
- Angela Bettis - Ida Williams
- David Chadwick - Larry Moll
- Jesse Hlubik - Jeffrey Flavors
- Elisa Lasowski - Mika
- Charlene McKenna - Maddie
- Neil Morrissey - Marcus
- Stewart Scudamore - Pete
- Benjamin Uttley - Mark
- Julien Vialon - Marcel Hulot
- Sarah Ball - Annabel
- Karina Minhas - Mandy
- Louise Downie - Miriam
- Janet Montgomery - Beth
- Naomi Allisstone - Margeritte
- Emma Stansfield - Pamela
- Daniel Black - Rider
- Alice Glass - Herself
- Lara Pulver - Victoria
- Kayvan Novak - Jake Abbasi
- Shameem Ahmad - Nurse
- Tim Downie - Mr. Jessup
- Davood Ghadami - Raj
- Hywel Morgan - Mark
- Ian Pink - Geeky Guy
- Amy Wren - Jane
- Tadas Gryn - Cop 2
- Tessa Bell-Briggs - Mrs. Rynkowski
- John Yorke
- George Faber
- Charles Pattinson
- Bryan Elsley
- Chris Clough
Mitch Hewer interpreta a Maxxie Oliver en la serie.
Ollie Barbieri interpreta a JJ Jones en la serie.
Joe Dempsie hace el papel de Chris Miles.
Dev Patel interpreta a Anwar Kharral en la serie.
Nicholas Hoult hace el papel de Tony Stonem.
Dakota Blue Richards interpreta a Franky Fitzgerald en la serie.
Mike Bailey interpreta a Sid Jenkins en la serie.
Merveille Lukeba interpreta a Thomas Tomone en la serie.
Megan Prescott hace el papel de Katie Fitch.
Larissa Wilson interpreta a Jal Fazer en la serie.
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