- Robert Gossett - Lt. Hudson
- David Grant Wright - Dr. Sterling Morton
- Shannon Whirry - Victoria Tremain aka Jenny Kravits
- Judith Chapman - Kathryn Walder
- Julie Caitlin Brown - Terri Roman
- Amy Weber - Rebecca Wharton
- Nicolas Coster - Liam Ryan
- William McNamara - Ev Carter
- Patrick Muldoon - Charles Lantman
- Melanie Smith - Jackie Ruis
- Jennifer Hetrick - Dinah Wharton
- James O'Sullivan - Phillip Wharton
- Salli Richardson-Whitfield - Shelley
- Gilbert Gottfried - Joey Mellman
- Melody Perkins - Maid
- Paul Schrier - Sonny Pacaro
- Michael Edwards - Digger
- Mary Fanaro - Tina Maxwell
- Vanity - Chantel
- Noah Blake - Ray Hogan
- Jason Tisi - Coroner's Assistant (uncredited)
- Patrick Wayne - Harmon Lange
- Kelly Curtis - Sarah Lawton
- Deanna Hurst - Proprietor
- Debbe Dunning - Marta
- Jordan Marder - Tommy Kingston
- Nancy Valen - Jillian Dupree
- Kate Hodge - Taylor
- Poppy Montgomery - Angel
- Jon Rashad Kamal - Milan Radovan
- Eric Pierpoint - Eric Russell
- Raye Birk - Atticus Dunn
- Michael Scott Greenlee - Bartender
- Gary Frank - Seaside Strangler
- William Jones - Hick #1
- Doug Waldo - Hick #2
- J. Trevor Edmond - Darren Langford
- Joseph R. Sicari - Mr. Patillo
- Paul Scherrer - Corey Gerschak
- Paul Scherrer - Tommy Brophy
- Casper Van Dien - Roger Barrows
- Kehli O'Byrne - Tonya
- Ann Turkel - Roxanne Dockweiler
- Avalon Anders - Beach Girl
- Avalon Anders - Bartender
- Avalon Anders - Girl in Gym
- Lindsey Ginter - Arthur Whitman
- Todd Eric Andrews - Willie Abbott
- Susanna Thompson - ADA Susan Harner
- Gary Hudson - Dr. Mark Hudson
- Patrick J. Andersen - Gator Ramsey
- Cindy Ambuehl - Vonnie Talbot
- Virginia Watson - Karen
- Mickey Manners - William Abbot, Jr.
- Bobbie Phillips - Tessa Shaver
- Danny Gans - Roger
- Forry Smith - Trent Armstrong
- Lauren Hays - Crystal
- Lauren Hays - Bev
- Cheryl Richardson - Gail Warden
- Lex Medlin - Ronnie Martin
- Alexandra Hedison - Julie
- Mitzi McCall - Fran Lipschitz
- Christopher Stanley - Peter Ricci
- Tess Broussard - Cyndi Parker
- Luca Bercovici - Lem Caine
- Jim Youngs - Johnny Rider
- Chuck Sloan - Dr. Bart Lincoln
- John Byner - Cotton Dunn
- Frank Noon - Buco
- Mark Sheppard - Eric
- Anthony Herrera - Ted Meyerson
- Elizabeth Savage - Dana Barclay
- Richard Gautier - Sonny Carlisle
- Jennifer Campbell - Cheryl Williams
- Ralph Elias - Geno
- Denise Gentile - Valerie Carlson
- Jared Martin - Garth Carlson
- Pierrette Grace - Kathleen Carlson
- Lucy Lin - Dr. Noriko Weinstein
- Rugg Williams - Eddie Weldon
- Patti Sheehan Hupp - Apartment Manager
- Zoe McLellan - Marin Kennedy
- Dennis Paladino - Donnie 'Dogs' DiBarto
- Megan Gallivan - Chynna McNeil
- Anthony Addabbo - Derek McNeill
- Anthony Addabbo - Nino Cunnetto
- Gayle Blakeney - Camilla Kincaid
- Gillian Blakeney - Priscilla Meadows
- Todd Kimsey - Nate Rockford
- Todd Kimsey - Erick Stark
- Deirdre Haj - Caprice Duncan
- Vanessa Dorman - Kimberly
- Scott Anderson - Clyde
- Kathy Trageser - Audrey Lowe
- Barbara Claman
- Stu Segall
- Derek Marcil
Chris Potter interpreta a Tom Ryan en la serie.
Janet Gunn interpreta a Cassandra St. John en la serie.
Charlie Brill interpreta a Harry Lipschitz en la serie.
David Grant Wright hace el papel de Dr. Sterling Morton.
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