- Tyra Banks - Mrs. Burke
- Carly Rae Jepsen - Self
- Jack Plotnick - Phil
- Cameron Boyce - Lil Highlighter Dancer
- Chris Trousdale - Justin Starr
- Wyatt Oleff - Byron / Kid
- Noah Centineo - Monroe
- Duncan Tran - Johnny B
- Philip Anthony-Rodriguez - Napoleon Fontaine
- Kenneth Tipton - Jungle Boogie
- Shannon Edwards - Rusty
- Renée Taylor - Mrs. Locassio
- Shane Giedraitis - Little Boy
- Robert Stilwell - Chicago Commuter
- Matthew Scott Montgomery - A.D.
- Sophia Ali - Tasha
- Steven Lee Allen - Steve
- Kent Boyd - Himself
- Fred Stoller - Sensei Ira
- Ryan Conferido - Lee
- Stephanie Lemelin - Karen Thomas
- Mitch Holleman - Xavier
- Garrett Clayton - Dylan
- Kiersey Clemons - Danielle
- Neal Lerner - Clark Stonehouse
- Alexandria DeBerry - Destiny
- Jordan A. Nichols - Joshua
- Cat Deeley - Vice Principal Winslow
- Thomas Kasp - Frankie
- Juliette Goglia - Savannah
- Caitlin Carmichael - Eileen Keller
- Emily Skinner - Sally Van Buren
- John D'Aquino - Don Rio
- Adrian Elizondo - Marco
- Charlet Chung - Candy
- Evie Thompson - Sarah
- Anneliese van der Pol - Ronnie
- Meagan Holder - Angie
- Zayne Emory - Howard
- Wendy Worthington - Ms. Lee
- Bronson Pinchot - Kashlack Hessenheffer
- Mary Birdsong - Squitza Hessenheffer
- Tony O'Dell - Kelly
- Jamie Kaler - Gordon Lesseur
- Jackie Debatin - Dr. Semple
- Harriet Sansom Harris - Dr. Pepper
- E.E. Bell - Mr. Block
- Gabriel Morales - Julio Roberto Torres
- Christopher Rich - Mayor Bartlett
- Spencer Daniels - Paul
- Hudson Thames - D'Artagnan
- Ben Savage - Andy Burns
- Alex McKenna - Sarah
- Noel Arthur - Security Officer
- Leslie Jordan - Theodore Van Glorious
- Jim Pirri - Uncle Frank
- Marissa Jaret Winokur - Ms. Nancy
- Adam Trent - Self
- Larry Miller - Larry Diller
- Ashley Boettcher - Suzy
- Stuart Pankin - Santa Claus
- Jonathan Slavin - Mark Taussig
- Kurt Long - Host
- Mary Jo Catlett - Elderly Woman
- Kerris Dorsey - Kat
- Jay Thomas - Dan Gold
- Ursula Burton - Ms. Andrews
- Loretta Devine - Marsha Sanders
- Skylar Fayre - CeCe Jones
- Nicholas Braico - Klaus Hessenheffer
- Mike Jerome Putnam - Judge Hamilton
- William Ragsdale - Announcer
- Teala Dunn - Gina
- Denyse Tontz - Gloria
- David Shatraw - Hank
- Jerry Sroka - Ira
- Eric Lutes - Snappy Sammy
- Rizwan Manji - John
- Steve Monroe - Ralph
- Bridget Shergalis - Abigail
- Tim Bagley - Principal Rabinoff
- Max Ehrich - Eddie (uncredited)
- Max Ehrich - Eddie
- Jaylen Barron - Melanie
- Markus Silbiger - Kevin
- Kira Kosarin - Raina Kumar
- Dean Cudworth - Tom
- Anita Gillette - Edie Wilde
- Suzi Barrett - Major Dance
- Justin Deanda - Justin
- Carlson Young - Danika Fitzgerald
- Gina St. John - Reporter
- Keone Young - Mr. Wantanabe
- Buddy Handleson - Henry Dillon
- Ally Maki - Keiko Ishizuka
- Albert Kuo - Ichiro Wantanabe
- Amy Okuda - Hideko Wantanabe
- Brian Tee - Mr. Itou
- Adam Wylie - Andy
- DeeDee Rescher - Shelley Goldfeder
- Karen Maruyama - Michi
- Anna Akana - Tomoka
- Adam Karelin - Howie
- Aaron Refvem - Jason
- Brittany Ross - Crystal
- Chase Austin - Louis
- Jonathan Spencer - Flynn of the Future
- Ada Mogilevsky - Lilly
- James Patrick Stuart - Lance
- Alfonso Ribeiro - Mr. Zigfield
- John Ales - Igor
- Alexander Chaplin - Sergei
- Phil Morris - Curtis Blue
- Matthew Glave - J.J. Jones
- Anthony Starke - Jeremy Hunter
- Lou Richards - Health Inspector
- Samantha Hanratty - Kristin Wibler
- Beth Lacke - Mrs. Larrabee
- George Lopez - George Martinez
- Joel Brooks - Mr. Polk
- Maggie Wheeler - Mrs. Garcia
- Yvette Nicole Brown - Madame Tiffany
- Leo Howard - Logan Hunter
- Andy McDermott - Etienne
- Ayesha Fraser - Samantha
- Olivia Holt - Young Georgia
- Carla Renata - Marcie Blue
- Ashlee Füss - Stacy Paruso
- Anita Barone - Georgia Jones
- Diane Delano - Nurse Barbara
- Carla Jeffery - Margie
- Jonathan Chase - Phil
- Michael Grant - Ricky
- R. Brandon Johnson - Gary Wilde
- Haley Lu Richardson - Shake It Up Dancer
- Olivia Gonzales - I.aM.mE
- Chris Thompson
- Rob Lotterstein
- Michael Corcoran
- Selena Gómez
Harriet Sansom Harris interpreta a Dr. Pepper en la serie.
Bronson Pinchot interpreta a Kashlack Hessenheffer en la serie.
Larry Miller interpreta a Larry Diller en la serie.
Bella Thorne hace el papel de CeCe Jones.
Zendaya interpreta a Rocky Blue en la serie.
Davis Cleveland interpreta a Flynn Jones en la serie.
Roshon Fegan hace el papel de Ty Blue.
Adam Irigoyen interpreta a Deuce Martinez en la serie.
Caroline Sunshine interpreta a Tinka Hessenheffer en la serie.
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