- Jessica Walter - Tabitha Wilson
- Dustin Milligan - Ethan Ward
- Matt Lanter - Liam Court
- Trevor Donovan - Teddy Montgomery
- Gillian Zinser - Ivy Sullivan
- Elisabeth Röhm - Bitsy Epstein
- Mekia Cox - Sasha
- Carly Rae Jepsen - Herself
- Kelly Blatz - Max
- Kelly Lynch - Laurel Cooper
- Gideon Emery - Kevin
- Margo Harshman - Detention Girl
- Elisabeth Harnois - The Blonde Blended
- Hallee Hirsh - Hannah
- Lauren London - Christina Worthy
- Greg Vaughan - Kai
- Tori Spelling - Donna Martin
- Travis Van Winkle - Jamie
- John Schneider - Jeffrey Sarkossian
- Steven Brand - Jason Epstein
- Marco Dapper - Milo
- Traci Dinwiddie - Madame Flanagan
- James Patrick Stuart - Charles Clark
- Lise Simms - Louise Collins
- Jessica Lucas - Kimberly McIntyre
- Rumer Willis - Gia Mannetti
- Lily Collins - Phoebe Abrams
- Sara Foster - Jennifer "Jen" Clark
- Brooklyn Sudano - Miss Austin
- Hal Ozsan - Mr. Cannon
- David Chisum - Greg
- Diablo Cody - Herself
- Michael Graziadei - Eric
- Noureen DeWulf - Nika Raygani
- Maureen Flannigan - Leslie
- Drew Tyler Bell - Foreign Car Guy
- Joe E. Tata - Nat Bussichio
- Aimee Teegarden - Rhonda Kimball
- Fabiana Udenio - Atoosa Shirazi
- Meghan Markle - Wendy
- Melinda Sward - Jacqueline
- Josh Henderson - Sean Cavanaugh
- Shannen Doherty - Brenda Walsh
- Jonathon Trent - Richard Carter
- Michael Trevino - Ozzie Cardoza
- Jennie Garth - Kelly Taylor
- Rich Morris - Mr. Hunt
- Maeve Quinlan - Constance Tate-Duncan
- Adam Gregory - Ty Collins
- Linda Gray - Victoria Brewer
- Christina Moore - Tracy Clark
- Cherilyn Wilson - Morgan
- Brandon Michael Vayda - Mike
- Kellan Lutz - George Evans
- Jana Kramer - Portia Ranson
- Ryan Doom - Steven Ward
- Michael Piccirilli - Antonio Garrett
- Chandra West - Gail McKinney
- Chantelle Barry - Nina
- Charlie Weber - Mark Holland
- Grant Gustin - Campbell Price
- Blake Hood - Mark Driscoll
- Matthew Florida - Julian
- Brandon W. Jones - Obnoxious Senior
- Grey Damon - Waiter
- Brennan Mejia - Jimmy
- Felix Ryan - Sully
- Manish Dayal - Raj Kher
- Justin Deeley - Austin Tallridge
- Anthony Azizi - Uncle Amal Shirazi
- Matt Cohen - Jeremy
- Summer Bishil - Leila Shirazi
- William Russ - Salty
- Rebecca Tilney - Doctor
- Megalyn Echikunwoke - Holly Strickler
- Cameron Goodman - Bree
- Julianna Guill - Savannah Montgomery
- Julianna Guill - Savanna Montgomery
- Kristina Apgar - Jane
- Maitland McConnell - Margo
- Lisa Waltz - Katherine Upton
- Chloe Bridges - Alexis
- Sarah Hagan - Alana
- Katherine Vanderlinden - Margene
- Tui Asau - Karim
- Stephen Amell - Jim
- Sean Wing - Nick
- Kellie Pickler - Sally Butler
- Chris L. McKenna - Patrick Westhill
- Tiffany Hines - Kat
- Bre Blair - Winter
- Leith M. Burke - Dr. Harris
- Brandy Norwood - Marissa Harris-Young
- Ryan Rottman - Shane
- Ray Wise - Dean Thomas
- Perez Hilton - Himself
- Vinny Guadagnino - Poker-Playing Celebrity
- Billy Ray Cyrus - Judd Ridge
- Dina Meyer - Sheila
- Martin Spanjers - Stanley
- Niall Matter - Greg
- Sarah Danielle Madison - Colleen Sarkossian
- Michelle Hurd - Rachel Gray
- Erik Eidem - J.D.
- Trent Ford - Fashion Design Instructor
- Janice Dickinson - Herself
- Arielle Kebbel - Vanessa Shaw
- Shaun Duke - Omar Shirazi
- Nick Ballard - Cadet Ross
- Will Kemp - Mitchell Nash
- Tania Raymonde - Sonia
- Eric Tiede - Hal Blor
- Nick Zano - Preston "PJ" Hillingsbrook
- Yani Gellman - Diego Flores
- Danielle Bisutti - Connie
- Emily Graham-Handley - Carla
- Dylan Neal - William Paddington
- Judith Moreland - Dr. Hall
- La Toya Jackson - Marilyn
- Catherine Haena Kim - Amanda Dean
- Diane Sellers - Sybil
- Nick Carter - Nick Carter
- Tanc Sade - Tom Moreno
- Robert Hoffman - Caleb Walsh
- Myndy Crist - Lawyer
- Pharrell Williams - Himself
- Chris Zylka - Jason
- Anoush NeVart - Mrs. Kher
- Federico Dordei - Eduardo
- Alexander DiPersia - Jeremy
- Patrick Sebes - Jared
- Kathleen M. Darcy - Dr. Harper
- Diana Gettinger - Ramona
- Zachary Ray Sherman - Jasper Herman
- Charles Parnell - Franklin Whitney
- Mandy Musgrave - Alexa
- Amber Wallace - Lila
- Ann Gillespie - Jackie Taylor
- René Ashton - Cynthia Bennet
- Wes Brown - Taylor Williams
- Ken Luckey - Jamie
- Debra Wilson - Teacher
- Riley Thomas Stewart - Sammy
- Angela Gots - Ms. Casey
- Trai Byers - Alec Martin
- Caitlin Thompson - Madison Stewart
- April Parker Jones - Dana Bowen
- Marie Avgeropoulos - Cassie McCoy
- Lee Garlington - Judge
- Mackenzie Astin - Doctor
- Ben Begley - Morgue Employee
- Riley Smith - Riley Wallace
- Peyton List - Lindsey Beckwith
- Jessica Parker Kennedy - Megan Rose
- Jason Thompson - Detective Thompson
- Lindsey McKeon - Suzanne
- Sam Daly - Sam
- Rob Mayes - Colin Andrews
- Nicole Paggi - Carrie Anne Monroe
- Ryan Lochte - Himself
- Ashley Roberts - Penny
- Carmen Electra - Vesta
- Nelly Furtado - Herself
- Amber Stevens West - Bryce Woodbridge
- Natalie Morales - Ashley Howard
- Ne-Yo - Himself
- Denise Richards - Gwen Thompson
- Abbie Cobb - Emily Bradford
- Anastasia Baranova - Reese Turner
- Brianne Moncrief - Felicity Hathaway
- Tegan Quin - Herself
- Sara Quin - Herself
- Robin Thomas - Charles Sanderson
- J.R. Ramirez - Billy
- Rita Ora - Herself
- David Paluck - Gym Owner
- Pete Wentz - Pete Wentz
- Caitlin Muelder - Marriage Counselor
- Patrick Stump - Patrick Stump
- Lyndon Smith - Michaela
- Andy Hurley - Andy Hurley
- Joey McIntyre - Rand Gunn
- Joe Trohman - Joe Trohman
- Alexie Gilmore - Elizabeth McManus
- David Lim - Prince Harry
- Ashley Jones - Amanda Barnard
- Jason Kennedy - Jason Kennedy
- Terrell Owens - Himself
- Coby Ryan McLaughlin - Chief Porter
- Wolfgang Puck - Himself
- Merrin Dungey - Therapist
- Noah Hunt - Bass Player
- Hina Abdullah - Sonja
- Tom DeTrinis - Matthew
- Kathryn Winslow - Noreen
- Robbie Jones - Jordan Welland
- Trent Garrett - bru dog
- Melissa Ordway - Sydney Price
- Bunnie Rivera - Maria
- Billy Snow - Waiter
- Adam Kaufman - Brock Paige
- Jordan Austin Smith - Dylan
- Brandi Glanville - Herself
- Davida Williams - Aaliyah
- Camille Grammer - Herself
- Nicole Hayden - Jennifer
- Bailey Noble - Hellen
- Gregory Kieth - Burly man
- Mark Wystrach - Tyler Crawford
- Josh Zuckerman - Max Miller
- Keke Palmer - Elizabeth Royce Harwood
- Robin Givens - Cheryl Harwood
- Blair Redford - Oscar
- Sydney Sweeney - Girl
- Olly Murs - Himself
- Edward Finlay - Richard
- Nancy O'Dell - Herself
- Natalia Cigliuti - Elena Burns
- Chandler Kinney - Olivia
- Amelia Rose Blaire - Laura Mathison
- Brianne Howey - Stacey
- Tom Virtue - Mr. Bergman
- Ryland Blackinton - Ryland Blackinton
- Nathan Peterson - Surfer Dude
- Alan Ritchson - Tripp Willinson
- Dan Wells - Security Guard
- Sarah Buehler - Student
- Sarah Buehler - Pierced reporter
- William H. Brown
- Terrence Coli
- Patrick Coleman
- Michael Pendell
- Brian George
- Liz Phang
William Russ interpreta a Salty en la serie.
Dina Meyer interpreta a Sheila en la serie.
Shenae Grimes-Beech interpreta a Annie Wilson en la serie.
Tristan Mack Wilds hace el papel de Dixon Wilson.
AnnaLynne McCord interpreta a Naomi Clark en la serie.
Jessica Stroup hace el papel de Erin Silver.
Michael Steger hace el papel de Navid Shirazi.
Jessica Lowndes hace el papel de Adrianna Tate-Duncan.
Matt Lanter hace el papel de Liam Court.
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