- Patrick Fabian - Jeremiah Lasky
- George Cheung - Chinese Professor
- Holland Taylor - Dean Susan McMann
- Nancy Stafford - Judith Trudell
- Robert Guillaume - Dr. Arthur Hemmings
- Ami Dolenz - Christy
- Victor Raider-Wexler - Professor Rich
- Steve Eastin - The Coach
- Lark Voorhies - Lisa Turtle
- Marv Albert - Marv Albert
- Don Mirault - Sky Diving Instructor
- Dean Scofield - Reverend Dunlap
- Elena Lyons - Sonya
- Chad Wood - The Wrestler
- Essence Atkins - Danielle Marks
- Mathea Webb - Woman
- Hillary Matthews - Woman
- Kelli Kirkland - Woman
- Jenny Cooper - Woman
- Matt Letscher - Rick
- Charles Carpenter - Frat Guy #1
- David Markus - Frat Guy #2
- Susan T. Collins - Julie
- Lisa Ann Russell - Girl
- Ara Celi - Theresa Alvarez
- James Gleason - Mr. Novak
- Charles Grant - Johnny Walters
- Gloria Loring - Mrs. Burke
- Edward Winter - Mr. Burke
- David DeLuise - Tony
- Danny Lee Clark - John Hammer
- Brittney Powell - Jennifer Williams
- John Fink - Chancellor Williams
- Eddie Cibrian - Janitor (uncredited)
- Tony Rizzoli - Mr. Savio
- Donna Barnes - Debi
- Jonathan Brandis - Jonathan Brandis
- Brian Austin Green - Brian Austin Green
- Dennis Haskins - Mr. Belding
- Jenna von Oy - Jenna von Oy
- Marsha Warfield - Marsha Warfield
- Eric Champnella - Assistant Director
- Marty York - Boy
- Jamie Renée Smith - Abby Lasky
- Jonathan Anderson - Husky Guy
- Mindy Sterling - Clara Meade
- Mary-Pat Green - Marlene
- Tim Griffin - Jason
- Jake Beecham - Stingray
- Alle Ghadban - Guy
- Diana Tanaka - Dr. Wong
- Adam Philipson - Bill
- Rod Biermann - Keith
- La Sondra Zarif - Customer
- Timothy Elwell - Nurse Gruen
- Frank Farmer - Minister
- Paul Kersey - Curtis
- Marty Rackham - Stan
- Kathy Jacobs - Cop
- Brittany Levenbrown - Zackerina
- Heather Elizabeth Parkhurst - Sally (uncredited)
Mark-Paul Gosselaar interpreta a Zack Morris en la serie.
Mario López hace el papel de A.C. Slater.
Dustin Diamond interpreta a Samuel 'Screech' Powers en la serie.
Anne Tremko hace el papel de Leslie Burke.
Kiersten Warren hace el papel de Alex Tabor.
Bob Golic interpreta a Michael Rogers en la serie.
Tiffani Thiessen hace el papel de Kelly Kapowski.
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