- Rip Torn - Alvah Clayhorne
- Jacqueline Courtney - Binky Klein
- Jeremy Slate - Hob Harrell
- Robert Redford - Janosh
- Bruce Glover - Truck Driver
- Sylvia Sidney - Lonnie Taylor
- Herschel Bernardi - Gerald Ward
- Douglas Fairbanks Jr. - Charles Clayton
- Leo Gordon - Bernie Duncan
- Anne Helm - Janie Nickerson
- Jo Van Fleet - Hazel Quine
- Janice Rule - Sidney Brookes
- Chester Morris - Emmett McNeill
- Chester Morris - Mr. Hull
- Lois Smith - Lucy Brown
- Lois Smith - Dana
- Diane Baker - Marie Duplessis
- Harvey Korman - Len Statler
- Joan Crawford - Morgan Harper
- Marion Ross - Nora Belden
- Anne Francis - Jana Johnson
- Dan Frazer - Bob Richards
- Lon Chaney Jr. - Poppa Duplessis
- Lon Chaney Jr. - Lon Chaney
- Lon Chaney Jr. - Colby
- Joseph Mell - Marty Epstein
- Robert Duvall - Lee Winters
- Burt Reynolds - Tommy
- Ed Asner - Second Man
- Michael Conrad - Al Jenkins
- Diana Van der Vlis - Nita Hull
- Tom Bosley - Dr. Summer Klein
- Tom Bosley - Jim Horst
- Patrick O'Neal - Leon Tiffin
- Patrick O'Neal - Eric
- Edgar Buchanan - Magistrate Abe Chumley
- Beatrice Straight - Elena De Amundo
- Jean Muir - Beatrice Ware
- Elena Verdugo - Elena
- Larri Thomas - Joy
- Robert Weil - Vendor
- Jimmy Carter - Alan Christopher
- Barbara Hines - Frieda
- David Janssen - Karno Starling
- Joseph Campanella - Whit Spencer
- Laura Devon - Toika Gustafson
- Signe Hasso - Anna Gustafson
- Phil Chambers - Clerk (uncredited)
- Selette Cole - Lois
- Lorraine Rogers - Andrea
- Lorraine Rogers - Pretty Girl
- Berkeley Harris - Robbie Beale
- Marco St. John - Johnnie Simmons
- Alan Alda - Dr. Glazer
- Clifton James - George Simmons
- Daniel J. Travanti - Marty Johnson
- Percy Rodriguez - Harry
- Joanna Pettet - Millie Wilkins
- Philip Abbott - Lieutenant Cook
- John Larch - Bill Morrison
- John Larch - Sandy Mason
- Jack Gordon - Derelict (uncredited)
- Joe E. Brown - Sam Butler
- Frank Overton - Hanson
- Frank Overton - Peter Graham
- Frank Overton - Andy Ferguson
- Frank Overton - Cord Webster
- John Davis Chandler - Frank Lauderbeck
- Bruce Dern - Albert
- John Astin - Gas Attendant
- John Astin - Benson
- Vera Miles - Ellen Barnes
- Stephen Brooks - Ralph
- Russell Johnson - Bob Keel
- Harold Gould - Edward Crane
- Harold Gould - Doctor
- Brooke Bundy - Sue Quine
- Oliver McGowan - Sheriff
- Tuesday Weld - Miriam Moore
- Cloris Leachman - Lydia Manning
- Roger C. Carmel - Otis Tiffin
- Roger C. Carmel - Man in the Shower
- Veronica Cartwright - Miriam Moore (Age 9)
- Patrick Cranshaw - Alfred (uncredited)
- James Westmoreland - Second Surfer
- Fred Stromsoe - Fighter on Balcony (uncredited)
- Fred Stromsoe - Carson (uncredited)
- Fred Stromsoe - Fighter in Bar (uncredited)
- Jack Lord - Gabe Johnson
- Harold J. Stone - Gus Patton
- Harold J. Stone - Lieutenant Mangano
- Ted de Corsia - Poker Player (uncredited)
- Bobby Jordan - Garage Attendant (uncredited)
- Alan Hale Jr. - Mr. Nickerson
- Nick Dimitri - Nick
- Kay Medford - Woman
- Paul Reed - Husband
- Robert Emhardt - Jackson Harris
- Robert Emhardt - Beale
- Albert Henderson - Bartender
- Alex Cord - Michael Tiffin
- Alex Cord - Rick Decatur
- Alex Cord - Raymond
- Alex Cord - Jack
- Elizabeth MacRae - Jean Cory
- Elizabeth MacRae - Betsy
- Elizabeth MacRae - Randy Spring
- Elizabeth MacRae - Betty
- Stefanie Powers - Julie Severn
- Barbara Eden - Margo Tiffin
- Barbara Eden - Margo Stiles
- Zohra Lampert - Sue Ellis
- Richard Shannon - Lou Gillis
- Donna Douglas - Dana
- Elizabeth Ashley - Maria Cardenas
- Mario Alcalde - Juan De Amundo
- Peter Brocco - Dr. Burton
- Charles Brown - Policeman
- Moultrie Patten - Attorney
- Harvey Lembeck - Zip
- Joseph Ruskin - Blinky Ober
- Mary Webster - Midge Foster
- Lewis Charles - Lew
- Forrest Compton - Jeff Stevens (uncredited)
- Gene Hackman - Motorist
- Paul Stanley
- William A. Graham
- Walter Grauman
- James Goldstone
- Richard Donner
- Lewis Allen
- John McGreevey
- Shimon Wincelberg
- William Kelley
- Gilbert Ralston
- Jack Turley
- Stirling Silliphant
Robert Duvall interpreta a Lee Winters en la serie.
Sylvia Sidney interpreta a Lonnie Taylor en la serie.
Robert Redford interpreta a Janosh en la serie.
Ted de Corsia interpreta a Poker Player (uncredited) en la serie.
Joe E. Brown hace el papel de Sam Butler.
Lois Smith interpreta a Dana en la serie.
Tuesday Weld interpreta a Miriam Moore en la serie.
Lon Chaney Jr. interpreta a Colby en la serie.
Glenn Corbett interpreta a Linc Case en la serie.
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