- Amy Manson - Daisy
- Dean Lennox Kelly - Tully
- Georgia Henshaw - Joy
- Erin Richards - Nancy Reid
- Morgan James - No. 7
- Glenn Doherty - Duncan
- Jason Watkins - Herrick
- Gregg Chillin - Owen
- Dylan Brown - Seth
- Jessica Harris - Becca
- Lizzie Roper - Maggie
- Alex Price - Gilbert
- Julia Ford - Fleur
- Mykola Allen - Bernie
- Barry Aird - Jim
- Mark Flitton - Shop Owner
- Clare Higgins - Josie
- Morgan Walters - Policeman
- Josef Altin - Billy
- John Hollingworth - Turlow
- Adam Deacon - Marco
- Donald Sumpter - Kemp
- Rick Bacon - Dr. Newell
- Abigail Davies - Paramedic
- Rhiannon Harper-Rafferty - Nurse
- Annabel Scholey - Lauren Drake
- Michael Begley - Chaplain Mark
- Lyndsey Marshal - Lucy
- Paul Rhys - Ivan
- Mark Fleischmann - Lloyd Pinkie
- Joel Gillman - Richard Galvin
- Alex Lanipekun - Saul
- Adrian Schiller - Hennessey
- Margaret John - Old Lady
- Steve John Shepherd - Carl
- John Stahl - Quinn
- Terry Wogan - Sir Terry Wogan
- Jonathan Aris - Newsreader
- Dan Mersh - Policeman
- Lauren O'Neill - Kirsty
- Ian Puleston-Davies - Chief Constable Wilson
- Pearce Quigley - Catholic Priest
- Bryan Dick - Sykes
- Lucy Gaskell - Sam Danson
- Vincent Franklin - Ross
- Federico Zanni - Pablo
- Molly Jones - Molly
- John Paul Hurley - Douglas
- Charlene McKenna - Josie
- Sara Pascoe - Kathleen
- Glyn Grimstead - Policeman
- Matt Barber - Young Kemp
- Simon Paisley Day - Alan Cortez
- Aimee-Ffion Edwards - Robin
- Morgan Jones - Jimmy
- Sally Ann Matthews - Orla
- Jacquetta May - Carmen
- David Webber - Train Worker
- Edward Franklin - Daniel
- Sara Gregory - Amy McBride
- Robson Green - Anthony McNair
- Gwynfor Jones - Paul Jameson
- Paul Kaye - Vincent
- Rhys Matthews - Policeman
- Kai Owen - Bob
- Lacey Turner - Lia Shaman
- Thaer Al-Shayei - Merek
- Tim Bevan - Mr. Jacobs
- Anita Reynolds - Nita Mawulawde
- Melanie Walters - Emma Hargreaves
- Mark Lewis Jones - Richard Hargreaves
- Alexandra Roach - Sasha
- Tony Maudsley - Graham
- Jonny Owen - Gethin
- Michelle Luther - Sadie
- Boyd Clack - Bazzer
- Nicola Walker - Wendy
- Marion Bailey - Ruth
- James Fleet - George Senior
- Justin Salinger - Cooper
- Danny Webb - Marcus
- Sarah Niles - Dr. Hayley Hamilton
- Giles Thomas - Custody Sergeant
- Scott Arthur - Policeman / Corpse
- Lee Ingleby - Edgar Wyndam
- Craig Roberts - Adam Jacobs
- Craig Roberts - Adam
- Gina Bramhill - Eve
- Darren Evans - Dewi
- Anthony Flanagan - Fergus
- Sean Francis - Lucas
- Andrew Gower - Nick Cutler
- Mali Harries - Lisa
- Alex Jennings - Griffin
- Tamla Kari - Pearl
- Louis Mahoney - Leo
- Mark Williams - Regus
- Russell Gomer - Dessie
- James Lance - Kirby
- Laura Patch - Michaela
- Ceri Mears - Custody Sergeant
- Lucy Robinson - Dr. Wilson
- Angus Wright - Dr. North
- Ella Ainsworth - Henrietta
- Sacha Dhawan - Pete
- Selina Griffiths - Yvonne
- Amanda Abbington - Golda
- Marshall Griffin - Kane
- Anthony O'Donnell - Emrys
- Mark Gatiss - Mr. Snow
- Matthew Ashforde - Isaac Daniels
- Fred Pearson - Archivist
- Michael Wildman - Milo
- Phil Davis - Captain Hatch
- Colin Hoult - Ian Crumb
- Claire Cage - Patsy
- Wayne Cater - Martin
- Madeleine Harris - Hetty
- Victoria Ross - Lady Catherine
- Ellie Kendrick - Allison Larkin
- Ellie Kendrick - Allison
- Jeremy Swift - Emil
- Toby Whithouse - Alistair Frith
- Ben Greaves-Neal - Oliver
- Hamza Jeetooa - Alan
- Martin Hancock - Leader
- Julian Barratt - Larry Chrysler
- Amanda Hale - Lady Mary
- Caitlin Richards - Hazel
- Ricky Grover - Bobby
- Kathryn Prescott - Natasha
- Gordon Kennedy - Brendan
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