- Hamish Macdonald - Self - Host
- Hamish Macdonald - Self - Guest Host
- Jordan B. Peterson - Self - Panellist
- Roxane Gay - Self - Panellist
- Bernard-Henri Lévy - Self - Panellist
- Catherine McGregor - Self - Panellist
- Jane Goodall - Self - Panellist
- Yánis Varoufákis - Self - Panellist
- Neil deGrasse Tyson - Self - Panellist
- Andrew Neil - Self - Panellist
- Nigel Kennedy - Self - Panellist
- Tim Flannery - Self - Panellist
- Anthony LaPaglia - Self - Panellist
- Christopher Hitchens - Self - Panellist
- Alexei Sayle - Self - Panellist
- David Suchet - Self - Panellist
- Brian Cox - Self - Panellist
- Armando Iannucci - Self - Panellist
- Cornel West - Self - Panelist
- Pauline Hanson - Self - Panellist
- Joan Baez - Self - Panelist
- Ben Elton - Self - Panellist
- Angela Bishop - Self - Panellist
- Howard Jacobson - Self - Panellist
- Austen Tayshus - Self - Panellist
- John Lennox - Self - Panellist
- Malalai Joya - Self - Panellist
- Melinda Tankard Reist - Self - Panellist
- Slavoj Žižek - Self - Panellist
- Daniel Hannan - Self - Panellist
- Paul R. Ehrlich - Self - Panellist
- ANOHNI - Self - Panellist
- Samantha Power - Self - Panellist
- Annabel Crabb - Self - Panellist
- Annabel Crabb - Self - Guest Host
- Michael E. Mann - Self - Panellist
- Lenny Henry - Self - Panellist
- Michael Franti - Self - Panellist
- Randa Abdel - Self - Panellist
- Marcia Langton - Self - Panellist
- Derryn Hinch - Self - Panellist
- Julian Burnside - Self - Panellist
- Dan Sultan - Self - Panellist
- Archie Roach - Self - Panellist
- Stella Kvam Young - Self - Panellist
- Jonathan Biggins - Self - Panellist
- Dee Madigan - Self - Panellist
- Missy Higgins - Self - Panellist
- David Bradbury - Self - Panellist
- Urthboy - Self - Panellist
- Anne Summers - Self - Panellist
- Tim Ferguson - Self - Panellist
- Deborah Conway - Self - Panellist
- Josh Thomas - Self - Panellist
- Mia Freedman - Self - Panellist
- Deborah Cheetham - Self - Panellist
- Jan Davis - Self - Panellist
- Ruby Wax - Self - Panellist
- William Dalrymple - Self - Panellist
- Gene Robinson - Self - Panellist
- Fred Nile - Self - Panellist
- Bill Gates - Self - Panellist
- Martha Wainwright - Self - Panellist
- Bill McKibben - Self - Panellist
- Haifaa al-Mansour - Self - Panellist
- Robert Manne - Self - Panellist
- Todd Sampson - Self - Panellist
- Magda Szubanski - Self - Panellist
- Kevin Rudd - Self - Panellist
- David Williamson - Self - Panellist
- David Suzuki - Self - Panellist
- Vince Sorrenti - Self - Panellist
- Mark Steyn - Self - Panellist
- Laurie Penny - Self - Panellist
- Alan Jones - Self - Panellist
- Faustina Agolley - Self - Panellist
- Kate Miller-Heidke - Self - Panellist
- Mark Bouris - Self - Panellist
- Jason Silva - Self - Panellist
- Rachel Griffiths - Self - Panellist
- Nana Mouskouri - Self - Panellist
- Clementine Ford - Self - Panellist
- Richard Dawkins - Self - Panellist
- A.C. Grayling - Self - Panellist
- Miriam Margolyes - Self - Panellist
- Barry Humphries - Self - Panellist
- Simon Callow - Self - Panellist
- Germaine Greer - Self - Panellist
- Nitin Sawhney - Self - Panellist
- Pamela Stephenson - Self - Panellist
- Billy Bragg - Self - Panellist
- Julia Baird - Self - Panellist
- Scott Morrison - Self - Panellist
- Lehmo - Self - Panellist
- Lily Serna - Self - Panellist
- Corinne Grant - Self - Panellist
- Peter Greste - Self - Panellist
- Tariq Ali - Self - Panellist
- Naomi Klein - Self - Panellist
- Satyajit Das - Self - Panellist
- David Marr - Self - Panellist
- Jeffrey Sachs - Self - Panellist
- James Bartholomew - Self - Panellist
- Julie McCrossin - Self - Panellist
- Matt Preston - Self - Panellist
- Craig Foster - Self - Panellist
- Anthony Field - Self - Musical Guest
- Lachlan Gillespie - Self - Musical Guest
- Simon Pryce - Self - Musical Guest
- Emma Watkins - Self - Musical Guest
- R. Nicholas Burns - Self
- Yael Stone - Self - Panellist
- Ayaan Hirsi Ali - Self - Panellist
- Jordan Nguyen - Self - Panellist
- Wendy Harmer - Self - Panellist
- Shaun Micallef - Self - Panellist
- Brooke Boney - Self - Panellist
- Julia Gillard - Self - Panellist
- Lawrence Krauss - Self - Panellist
- Gus Worland - Self - Panellist
- Anthony Albanese - Self - Panellist
- Sarah Blasko - Self - Musical Guest
- Jenny Hocking - Self - Panellist
- Rutger Bregman - Self - Panellist
- Jimmy Barnes - Self - Panellist
- Grace Tame - Self - Panellist
- Jeff McMullen - Self - Panellist
- Tim Freedman - Self - Panellist
- Lindsay Tanner - Self - Panellist
- Lally Katz - Self - Panellist
- Corey White - Self - Panellist
- Dave Hughes - Self - Panellist
- Bridie Connell - Self - Musical Guest
- Raina MacIntyre - Self - Panellist
- Rae Johnston - Self - Panellist
- Sharon Lewin - Self - Panellist
- Rhys Muldoon - Self - Panellist
- Lionel Shriver - Self - Panellist
- DeRay Mckesson - Self - Panellist
- Steve Coll - Self - Panellist
- Christa Hughes - Self - Panellist
- Tristan Harris - Self - Panellist
- Marc Fennell - Self - Panellist
- Mojo Juju - Self - Panellist
- Tex Perkins - Self - Panellist
- Debbie Kilroy - Self - Panellist
- David Bridie - Self - Panellist
- Benjamin Law - Self - Panellist
- G Flip - Self - Musical Guest
- Alastair Campbell - Self - Panellist
- L-FRESH The LION - Self - Panellist
- Katie Noonan - Self - Panellist
- Maggie Beer - Self - Panellist
- Nakkiah Lui - Self - Panellist
- Meyne Wyatt - Self - Panellist
- Nayuka Gorrie - Self - Panellist
- Ashton Applewhite - Self - Panellist
- Tracey Holmes - Self - Panellist
- Fran Kelly - Self - Guest Host
- Jeremy Fernandez - Self - Panellist
- Isabel Allende - Self - Panellist
- Brendon Gale - Self - Panellist
- Paul Kelly - Self - Musical Guest
- Adam Liaw - Self - Panellist
- Charles Firth - Self - Panellist
- Kate Crawford - Self - Panellist
- Marlon Williams - Self - Musical Guest
- Harriet Harman - Self - Panellist
- Yumi Stynes - Self - Panellist
- Bruce Pascoe - Self - Panellist
- Thomas Piketty - Self - Panellist
- Teela Reid - Self - Panellist
- Stan Grant - Self - Panellist
- Stan Grant - Self - Guest Host
- Malcolm Turnbull - Self - Panellist
- Narelda Jacobs - Self - Panellist
- Courtney Act - Self - Panellist
- Jess Hill - Self - Panellist
- Linda Burney - Self - Panellist
- Julia Stone - Self - Musical Guest
- Luke McGregor - Self - Panellist
- Sameena Zehra - Self - Panellist
- Jennifer Robinson - Self - Panellist
- Sally Scales - Self - Panellist
- Cameron Murray - Self - Panellist
- Tom Elliott - Self - Panellist
- Peter Singer - Self - Panellist
- Katie Allen - Self - Panellist
- Santilla Chingaipe - Self - Panellist
- Virginia Trioli - Self - Guest Host
- Meshel Laurie - Self - Panellist
- Russel Howcroft - Self - Panellist
Barry Humphries interpreta a Self - Panellist en la serie.
Simon Callow interpreta a Self - Panellist en la serie.
Alexei Sayle interpreta a Self - Panellist en la serie.
Rachel Griffiths interpreta a Self - Panellist en la serie.
Hamish Macdonald hace el papel de Self - Host.
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