- Jon Hamm - Self - Celebrity Guest
- Heidi Klum - Self - Celebrity Guest
- Meghan Trainor - Self - Celebrity Guest
- Martin Short - Self - Celebrity Guest
- J.B. Smoove - Self - Celebrity Guest
- Chelsea Handler - Self - Celebrity Guest
- Tony Hale - Self - Celebrity Guest
- Yvette Nicole Brown - Self - Celebrity Guest
- Joel McHale - Self - Celebrity Guest
- Chrissy Metz - Self - Celebrity Guest
- Jon Cryer - Self - Celebrity Guest
- Joe Manganiello - Self - Celebrity Guest
- Chance the Rapper - Self - Celebrity Guest
- Jimmy Kimmel - Self - Celebrity Guest
- Nikki Garcia - Self - Celebrity Guest
- Brie Garcia - Self - Celebrity Guest
- Laverne Cox - Self - Celebrity Guest
- Liza Koshy - Self - Celebrity Guest
- Howie Mandel - Self - Celebrity Guest
- Lauren Graham - Self - Celebrity Guest
- Johnny Knoxville - Self - Celebrity Guest
- Wiz Khalifa - Self - Celebrity Guest
- Roy Wood Jr. - Self - Celebrity Guest
- Erin Dellorso
Martin Short hace el papel de Self - Celebrity Guest.
Keke Palmer hace el papel de Self - Host.
Jimmy Fallon interpreta a Self en la serie.
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