- Anjelica Huston - Clara Forsythe Allen
- Frederic Forrest - Blue Duck
- Barry Corbin - Roscoe Brown
- Chris Cooper - July Johnson
- William Sanderson - Lippy Jones
- Timothy Scott - Pea Eye Parker
- Barry Tubb - Jasper Fant
- Gavan O'Herlihy - Dan Suggs
- Frederick Coffin - Big Zwey
- Travis Swords - Allan O'Brien
- Kevin O'Morrison - Doctor
- Ron Weyand - Old Hugh
- Lanny Flaherty - Soupy Jones
- James McMurtry - Jimmy Rainey
- Sonny Carl Davis - Bert Borum
- Pierre Epstein - Xavier Wanz
- Helena Humann - Peach Johnson
- John Quijada - Pedro Flores
- Wallace Merck - Fowler
- Robert Donley - Old Sam
- Matthew Cowles - Monkey John
- David Ode - Dog Face
- O-Lan Jones - Sally Skull (as Olan Jones)
- Paul James Vasquez - Buffalo Hunter
- Brandon Smith - Bartender
- Jordan Lund - Hutto
- Matthew Posey - Jim #1
- Michael Tylo - Dee Boot
- Nada Despotovich - Mary
- Margo Martindale - Buffalo Heiffer
- Vern Porter - Dr. Arandel
- Danny Kamin - Captain Weaver
- Tony Epper - Dixon
- Boots Southerland - Sergeant
- Michael Pritchard - First Cowboy
- Adam Taylor - Deputy #1
- Todd Merrill - Reporter
- John Barks - First Trapper (as John Bark)
- Ed Geldart - Undertaker
- Curtis Taylor - Blacksmith
- David Little - Sheriff
- Kenny Call - Deputy #2
- Joel Palmer - Luke Wyatt
- Bud Shrake - Sodbuster
- Larry McMurtry
- William D. Wittliff
- Dyson Lovell
- Robert Halmi Jr.
- Michael Weisbarth
- Suzanne de Passe
O-Lan Jones interpreta a Sally Skull (as Olan Jones) en la serie.
Margo Martindale hace el papel de Buffalo Heiffer.
Robert Duvall interpreta a Augustus "Gus" McCrae en la serie.
Tommy Lee Jones hace el papel de Woodrow F. Call.
Diane Lane interpreta a Lorena Wood Parker en la serie.
Robert Urich hace el papel de Jake Spoon.
D.B. Sweeney interpreta a Dish Boggett en la serie.
Danny Glover interpreta a Joshua Deets en la serie.
Ricky Schroder interpreta a Newt Dobbs en la serie.
Glenne Headly interpreta a Elmira Boot Johnson en la serie.
Capítulo disponible en las siguientes plataformas:
