- Dan Cortese - Scott
- Rachael Harris - Margaret
- Nicole Richie - Ashley
- Erik von Detten - Erik
- Rory Thost - Young C.J.
- Connie Sawyer - Louise's Mother
- Shawn Pyfrom - Jake
- Erin Sanders - Riley
- Gabrielle Reece - Maggie
- Mary Page Keller - Traci
- Leighton Meester - Nikki
- Don Knotts - Ralph Furley
- Jason Priestley - Carter Tibbits
- Tiffany Thornton - Marni
- Raquel Welch - Jackie
- Lisa Rinna - Holly
- Ed Marinaro - Byron
- Keir O'Donnell - Derek
- Micah Alberti - Justin
- Colby Donaldson - Shawn
- Pamela Anderson - Cheryl
- Lee Corso - Sportscaster
- Lily Gibson - Sabrina
- Suzy Nakamura - Mrs. Krupp
- Connie Stevens - Tina
- Elena Lyons - Sissy
- Michael Kostroff - Photographer
- Lindze Letherman - Megan
- Ed O'Neill - Matt
- Nick Carter - Ben
- Shelley Long - Mary Ellen
- Michael Burger - Anthony's Father
- Daniella Monet - Missy
- Sam Horrigan - Pete
- Robert Guillaume - Cody Grant
- Kenneth Kimmins - Mr. Kolodny
- Tom McGowan - Frank
- Rachel Bilson - Gum Chewing Girl
- Mo Gaffney - Mrs. Connelly
- Paul Wesley - Damian
- Phill Lewis - Cop
- Ethan Phillips - Dave
- Chris Fowler - Sportscaster
- Jere Burns - Commissioner
- Adam Arkin - Ed Gibb
- Tom Poston - Jake
- Kyle Howard - Bruno
- Andi Eystad - Annie
- Eric Jungmann - Max
- Gloria Gifford - Teacher
- Kala Savage - Lacey
- Rachelle Carson - Woman
- Michael Milhoan - Mr. Edwards
- Tatum O'Neal - Ms. McKenna
- Michael McMillian - Guy
- Tracie Savage - TV Reporter
- Naya Rivera - Nice Girl
- Danny Woodburn - Lyle
- Carlie Casey - Katie
- Kimberly Kevon Williams - Maya
- Amanda Fuller - Lindsay
- Dempsey Pappion - Jessie
- Steven Gilborn - Clerk
- Patrick Warburton - Nick
- Matt Lanter - Brendon
- Lynn Manning - Blind Man
- Heather Hogan - Heather
- Heather Hogan - Leifer
- Cybill Shepherd - Maggie
- Vanessa Lengies - Monica
- Terry Bradshaw - Steve Smith
- Charlie Babcock - Luke
- Jan Hoag - Secretary
- Ruben Studdard - Guy
- Bryan Neal - Jesse
- Edward James Gage - Security Guard
- Wendie Jo Sperber - Rachel
- Wendie Jo Sperber - Louise
- Brian Leckner - Officer Jackson
- Kit Pongetti - Ms. Hunter
- Matt Funke - Travis
- Stephanie C. Allen - Angel
- Oleg Zatsepin - Care Bear
- Lee Garlington - Fran
- Lee Garlington - Leslie
- Shelly Cole - Christina
- Jenny Wade - Helga
- Brian Sites - Jason
- Kaitlin Cullum - Alison
- Kaitlin Cullum - Beth
- Romy Walthall - DIane
- Nick Lashaway - Boy #1
- Jake Dinwiddie - Boy #2
- Ashley C. Nelson - Sandy
- Ashlynn Rose - Mary Maureen
- Jeff Tschida - Tyler
- John Ratzenberger - Fred
- Dana Workman - Ashley
- Dana Workman - Lynzee
- Monique Lea-Gall - Shalindsay
- Monique Lea-Gall - Student
- Thad Luckinbill - Donny
- Cindy Williams - Mary Ellen
- Larry Miller - Tommy
- Amanda MacDonald - Danielle
- Lindsey Fields - Helen
- Michele Matheson - Receptionist
- Liam Kyle Sullivan - Zac
- Liam Kyle Sullivan - Duane
- Todd Merrill - Man
- Suzanne Pleshette - Laura
- Jordi Vilasuso - Luke
- Cole Williams - Anthony
- Steve Vinovich - Director
- Carl Weintraub - Joe
- Talia-Lynn Prairie - Gayle
- Will Schaub - Vic
- Myrna Niles - Hattie
- Allison Andreas - Sarah
- Deborah Levin - Teacher
- Patrick S. Harrigan - Flower Vendor
- Jonathan Taylor Thomas - Jeremy
- Howard Alonzo - Andre
- Howard Alonzo - Russell
- Peter Bogdanovich - Dr. Lohr
- Marcus A. York - Construction Guy
- Jonny Acker - Ric
- Inny Clemons - Supervisor
- Marcus Toji - Manager
- Peter Gannon - Bartender
- Billy Aaron Brown - Kyle
- Mac Davis - Guitar Man
- Marisa Theodore - Marisa
- Marisa Theodore - Megan
- Michael Faella - Trucker
- Sarah Domin - Heather
- Rhomeyn Johnson - Instructor
- John Farley - Owner
- Nicole Hayden - Jenna
- Josh Henderson - Tyler
- Donna Cooper - Mall Shopper
- Ronnie Alvarez - Boy
- Rocky McMurray - Door Man
- Dennis Singletary - Mike
- Sarah Rafferty - Danielle
- Kimberly McConnell - Rebecca
- David Garry - Robert
- Nicholas Edwin Barb - Joey
- Andy Morrow - Billy
- Kristin Brey - Heather
- Beth Grant - Mrs. Whitley
- Darryl Sivad - Coach
- Rachel Melvin - Cute Girl
- Sebastian Feldman - Crew Guy #3
- Tom Shadyac
- James Widdoes
Cybill Shepherd hace el papel de Maggie.
Wendie Jo Sperber interpreta a Louise en la serie.
Larry Miller interpreta a Tommy en la serie.
Katey Sagal interpreta a Cate Hennessy en la serie.
Kaley Cuoco interpreta a Bridget Hennessy en la serie.
Amy Davidson interpreta a Kerry Hennessy en la serie.
Martin Spanjers interpreta a Rory Hennessy en la serie.
James Garner interpreta a Jim Egan en la serie.
David Spade interpreta a C.J. Barnes en la serie.
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