- Dylan Walsh - Sean McNamara
- Kelly Carlson - Kimber Henry
- Rhona Mitra - Kit McGraw
- Lindsay Hollister - Nanette Babcock
- Joel McKinnon Miller - Duke Collins
- Phina Oruche - Mia
- Willam Belli - Cherry Peck
- Leslie Grossman - Bliss Berger
- Brittany Snow - Ariel Alderman
- Lily Rabe - Lanie Ainge
- Maggie Siff - Rachel Ben Natan
- Phillip Rhys - Jude Sawyer
- Sophia Bush - Ridley Lange
- AnnaLynne McCord - Eden Lord
- Jacqueline Bisset - James LeBeau
- Kate Mara - Vanessa Bartholomew
- Jill Clayburgh - Bobbi Broderick
- Julie Warner - Megan O'Hara
- Portia de Rossi - Olivia Lord
- Lauren Hutton - Fiona McNeil
- Sarah Paulson - Agatha Ripp
- John Schneider - Ram Peters
- Brian Kerwin - Eugene Alderman
- Alex Carter - Cliff Mantega
- Luis Antonio Ramos - Nico Scamarel
- Jackie Debatin - Nancy Collins
- Gerry Becker - Robert Bartholomew
- Linda Klein - Nurse Linda
- Colleen Flynn - Dr. Allamby
- Brooke Shields - Faith Wolper
- Jane Daly - Doctor
- Felix Ryan - Mime #2
- Christine Adams - Dr. Sarah Kwinda
- Daylon Reese - Kid #4
- Elisa Eliot - Rhinoplasty Patient (uncredited)
- Jessalyn Gilsig - Gina Russo
- Richard Gautier - Marshall Ayers
- Dita de Leon - Silly Bimbo
- Amber Strauser - Beautiful Redhead
- Shana Wall - Sunbather
- Jennifer Coolidge - Candy Richards
- Jennifer Coolidge - Candy Richards, Coco
- Natalija Nogulich - Shirley
- Sean Donnellan - Guard
- Barry Ratcliffe - Forensic Pathologist
- Rob Mars - Diver Guide
- Mary Pat Gleason - Carol McCrackin
- Keith Pillow - Doctor
- Daniel Polo - Duke's Son
- Tedd Szeto - Caroler #1
- Bret Shefter - Caroler #4
- Rico Rodriguez - Kid #1
- Saige Ryan - Little girl
- Eddie Alfano - Danny
- Eli Jane - Model
- Natalina Maggio - Persian Porn Star
- Iris Fridmey Sturludottir - Stripper
- Daphne Zuniga - Carly Summers
- Dylan Ramsey - Saaed Hotary
- Craig Reed - Construction Worker
- Jennifer Salt
- Lynnie Greene
- Brad Falchuk
- Michael M. Robin
- Greer Shephard
Lily Rabe hace el papel de Lanie Ainge.
Dylan Walsh hace el papel de Sean McNamara.
Julian McMahon hace el papel de Christian Troy.
Joely Richardson hace el papel de Julia McNamara.
John Hensley interpreta a Matt McNamara en la serie.
Roma Maffia hace el papel de Liz Cruz.
Kelly Carlson hace el papel de Kimber Henry.
Capítulo disponible en las siguientes plataformas:
