- Ricardo Montalban - Colonel Diego Alcazar
- Bo Hopkins - Kansas
- Dabbs Greer - Harrigan
- Harry Hickox - Commanding Officer
- Owen Bush - Conductor
- Armand Alzamora - Raoul
- Vernon Weddle - Reporter
- Chuy Franco - Alfredo
- Michael Tolan - Flying Fox
- James Greene - Lou Feeny
- Judson Pratt - Trencher
- Wayne Heffley - Team Leader
- Wayne Heffley - Major
- Wayne Heffley - Cavalry Major
- Britt Leach - Clerk
- Eddie Quillan - Agent
- Joyce Van Patten - Arletta McGreevy
- John Rubinstein - Fred Buckerman
- Ray Reinhardt - Duffield
- Tracy Bogart - Susan
- Ray Danton - Juan
- Gene Evans - Durand
- William Bramley - Hemmings
- Ralph Waite - Sam Burton
- Don Keefer - Burt Lincoln
- Michael Baseleon - Willy Brownfur
- Henry Beckman - Murphy
- Robert F. Simon - Slade
- Charles Dierkop - Nose
- Poupée Bocar - Carmen
- Ralph James - Kitchen Boss
- Med Flory - Cyrus
- William Paterson - Banker Perkins
- William Paterson - Perkins
- Don Newcombe - George Henry
- Alan Oppenheimer - Averrel
- E.J. André - Hargut
- E.J. André - Ed Hargut
- Clifford David - Billings
- Don Pedro Colley - Joe Cramm
- Hoke Howell - Ernie
- Kristoffer Tabori - Frankie
- Roy Jenson - Bull
- Walter Burke - Hartford
- Jerry Summers - Fred
- Lillian Bronson - Old Lady
- Edith Leslie - Bartender
- Steve Forrest - Sam Yeager
- Stefan Gierasch - Doc Bernstein
- John Daheim - Railroad Detective
- Ted Gehring - Henry
- Ted Gehring - Railroad Executive
- Richard Yniguez - Casado
- Charles McGraw - Luke
- Charles McGraw - Hansen
- Catlin Adams - Mabel Zimmerman
- Jesse Vint - Charlie Springer
- Bill Vint - Springer Brother
- Alan Vint - Springer Brother
- Paul Hampton - Johnson
- John Crawford - Marshall
- John Crawford - Sgt. Kessler
- John Quade - Scully One
- John Quade - Zeb
- Robert Gist - Gulley
- Robert Gibbons - Dentist
- Dana Derfus - Blacksmith
- Bennie E. Dobbins - Ben
- Tom Skerritt - Charley Doyle
- Gerald S. O'Loughlin - Roarke
- Susan Tyrrell - Caralee
- Paul Winfield - Eddie Joe
- Warren Vanders - Pel De Carlo
- Eric Laneuville - Stove Boy
- James Daris - Curtiss
- Florence Lake - Old Lady
- Florence Lake - Mrs. Prine
- Lou Frizzell - Warden
- Scatman Crothers - Jack
- Jester Hairston - Melville
- Napoleon Whiting - Preacher
- Strother Martin - Zachariah
- Barry Cahill - Logan
- Marc Lawrence - Prouty
- James Beach - Bob Sanders
- James Beach - Sanders
- Edward Faulkner - Randall
- Noam Pitlik - Jack Stone
- Jennifer Gan - Gloria
- Liam Dunn - Fingers
- Rayford Barnes - Axel
- Rayford Barnes - Ellsberg
- Orwin C. Harvey - Ray
- Regis Cordic - Tyler
- Chuck Hicks - Steve
- Chuck Hicks - The Dutchman
- Jonathan Goldsmith - Ralph
- Frederic Downs - Sam
- Jack Garner - Van Vechten
- Jack Elam - Marcus A.F. Baxter
- Fran Ryan - Minnie Dowd
- Vincent Van Patten - Grover
- Dort Clark - Sheriff
- Richard Stahl - Doc
- Richard Stahl - Doc Bernstein
- Rance Howard - Deputy
- Dennis Robertson - Kenneth
- Paul Brinegar - Gaffer
- Charles Knapp - Turpin
- H.B. Haggerty - Gentleman George
- Ed Flanders - Harlan B. Flanders
- Harvey Parry - Referee
- Lou Wagner - McKeever
- Kelly Thordsen - Jacob Klaus
- Richard Bull - Thatcher
- M. Emmet Walsh - Gabe McCutcheon
- Nora Marlowe - Mrs. Goudge
- Olan Soule - Mr. Goudge
- Kay E. Kuter - Jensen
- Allyn Ann McLerie - Maggie
- Val Avery - Jasper
- Ramon Bieri - Cutler
- Jay Varela - Sin Lingua
- Priscilla Garcia - Juanita
- Anthony Zerbe - Quinn
- Marge Redmond - Juanita
- John Harding - Salter
- Russ McCubbin - Donnie
- Alice Ghostley - Bertha
- Luis Delgado - Luis
- Gale Dixon - Lucinda
- Karl Lukas - Harry Carmichael
- Eve Bruce - Hazel
- Marie Gahva - Maria
- Sandy Brown Wyeth - Alice
- Barbara Collentine - Charlotte
- William Christopher - Niles
- Buck Kartalian - Samuel
- Gregg Palmer - Burt
- Herman Poppe - George
- Larry Gelman - Cronie
- Harry Harvey - Man
- Harry Harvey - Irate Citizen
- Frank Pierson
- Meta Rosenberg
- Michael Zinberg
- Joe Scully
- Bernardo Segall
Ricardo Montalban interpreta a Colonel Diego Alcazar en la serie.
Paul Winfield hace el papel de Eddie Joe.
Tom Skerritt interpreta a Charley Doyle en la serie.
Marc Lawrence interpreta a Prouty en la serie.
M. Emmet Walsh hace el papel de Gabe McCutcheon.
Val Avery interpreta a Jasper en la serie.
Anthony Zerbe interpreta a Quinn en la serie.
Margot Kidder interpreta a Ruth en la serie.
James Garner interpreta a Sheriff Frank Nichols en la serie.
John Beck hace el papel de Ketcham.
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