- James Dunn - Peter Wilkin
- Lois Smith - Dawn Garrison
- William Daniels - Harry Culverin
- Norman Rose - Abe Ornitz
- Abraham Sofaer - Ling Twong
- Kent Smith - George Blake
- Luke Halpin - Kid #2
- Eileen Fulton - Janie Daggett
- Dan Tobin - Charles Banning
- Barbara Loden - Penny Sonners
- Terry Carter - Jack Lubin
- Henderson Forsythe - Dr. Hennickson
- Jack Lord - Cary Glennon
- Frank Overton - Andrew Bates
- Jerome Cowan - Carl Terris
- Robert Walker Jr. - Neil McCaw
- Peggy Ann Garner - Edie Brewer
- Lee J. Cobb - Paul Delito
- Kathryn Hays - Beth Rydecker
- James Farentino - Ben Calageras
- Karen Steele - Grace Harvey
- Robert Redford - Baldwin Larne
- George Rose - George Lanyard McGraff
- Telly Savalas - Gabriel Hody
- Diana Hyland - Vivian North
- Lee Philips - Larry Hine
- Richard Conte - Phil Clifford
- Brett Somers - Mrs. Garvin
- Frances Heflin - Josephine Hendon
- Estelle Evans - Crossing Guard
- Chester Morris - Frank Manfred
- Dorothy Peterson - Mrs. Graither
- Michael Ansara - Rafael Valente
- Nancy Carroll - Bernice Hacker
- John Karlen - Chuck
- Martine Bartlett - Receptionist
- Carlos Montalbán - Frank Baker
- Perry Lopez - Howard Running Bear
- Roxanne Arlen - Nona Kovar
- Mark Rydell - Ralph Harris
- Alejandro Rey - Jaime deJesus
- Cara Williams - Lois Heller
- Sam Jaffe - Lazslo Lubasz
- House Jameson - Morgan
- Luis van Rooten - Mr. Binks
- David Winters - Marty Nemo
- Patrick Waddington - Mitcham
- Val Avery - Franko
- George S. Irving - Butcher
- Gerald S. O'Loughlin - Mr. Hackett
- Geraldine Brooks - Vicky
- Al Hodge - Johnson
- John McQuade - Cassidy, Gangster
- Bernard Kates - Bobby Madison
- Simon Oakland - Duke
- George Segal - Jerry Costell
- James Shigeta - James Kam
- Sandy Baron - Charley Breggs
- Zina Bethune - Jessica Glennon
- Ernest Graves - Lawyer
- Marco St. John - Dom Capado
- Logan Ramsey - Beau Choiseul
- Franklin Cover - Steelworker
- George C. Scott - Kermit Garrison
- Joseph Bernard - Assistant D.A. Colby
- David Wayne - Herbert Konish
- Mae Questel - Mrs. Annette Faber
- Fay Spain - Felice Reynolds
- Tuesday Weld - Ora Mae Youngham
- Diana Van der Vlis - Linda Stephenson
- Milt Kamen - Officer Novi
- Richard Jaeckel - Lance
- Deborah Walley - Heather Weston
- Barbara Baxley - Kathy McDavoran
- Robert Blake - Knox Maquon
- Robert Alda - Jess Burton
- David Clarke - Attacker
- Steven Hill - Stanley Walenty
- Celia Adler - Old Woman
- Gary Morgan - Paulie
- Kirk Alyn - Sgt. Muller
- Vic Morrow - David Greco
- Sylvia Sidney - Florence Nunda
- John S. Ragin - Mr. Warstein
- Roddy McDowall - Donnie Benton
- Alexander Scourby - Walter Gerrick
- Joe De Santis - Matt Valentine
- Dennis Hopper - Vinnie Winford
- Frank Gorshin - Alan Starkie
- Glynis Johns - Miss Arlington
- James Caan - Marty Feketi
- Richard Hamilton - Philip Hames
- Claude Dauphin - Ogier Douvay
- Henry Hull - Alky
- Gabriel Dell - Willie Corbin
- Jon Voight - Victor Binks
- James Coburn - Harry Brind
- Frank Marth - Albert Garvin
- David Doyle - Dan Moore
- Anne Seymour - Mrs. Beatrice Shaw
- Anthony Dawson - Mike Grundy
- Bradford Dillman - Roger Fallon
- Percy Rodriguez - Millard Jeffers
- Erik Rhodes - Gardell
- Neva Patterson - Miss Morley
- Steve Cochran - Niccolo Mori
- Daniel H. Jenkins - Josh
- Joan Copeland - Beverly Lewine
- Cicely Tyson - Darlene Knox
- Louis Nye - The Drunk
- James Patterson - Phil North
- Rosemary Murphy - Lillian (uncredited)
- Lawrence Tierney - Mike Jensen
- Ruth Ford - Mrs. Rydecker
- Elizabeth MacRae - Lorri
- Nancy Wickwire - Norma Rhodes
- Jack Kruschen - Dean Fairland
- Felicia Farr - June Waldon
- Nancy Marchand - Esther Lindall
- Phyllis Hill - Betty Fleischman
- Phyllis Hill - Jane Whitmore
- Ruth McDevitt - Abbie Dobbins
- Mickey Rooney - George Bick
- Hume Cronyn - Professor Henry J. Fallon
- Jesse White - Harold Slate
- Jo Van Fleet - Dr. Anna Chaloupka
- Gladys Cooper - Mrs. Ernest Johns, Sr.
- Rocky Graziano - Lou Curtis
- Rocky Graziano - Eddie Gibbs
- Vaughn Taylor - J. Milton Turpin
- Stuart Damon - Lt. J.G. Marks
- Diane Ladd - Kathie Mills
- Diane Ladd - Yankee Cretias
- Barbara Harris - Helga Royd
- Patricia Bosworth - Laura
- Patricia Bosworth - Betty Harkness
- Richard Basehart - Lester Bergson
- Suzanne Pleshette - Nora Condon
- Keir Dullea - Les Gerrick
- Keir Dullea - Joseph Ross
- Ulla Jacobsson - Karen Gunnarson
- Betty Field - Pauline Kater
- Betty Field - Mrs. Brent
- Richard S. Castellano - Bartender (uncredited)
- Romo Vincent - Teddy Simpson
- Bruce Dern - Nicky
- Paul Hartman - Ben Stringfellow
- Paul Hartman - Rummy Brent
- Allan Rich - Cab Driver
- Nico Minardos - Moktir
- Barnard Hughes - 1st Reporter
- Joanna Merlin - Gloria Werminski
- Warren Finnerty - Frankie Valens
- Claude Rains - John Winfield Weston
- Leslie Nielsen - Norman Garry
- Bethel Leslie - Amy Langan
- Michael McGreevey - Mickey McDavoran
- Richard Jordan - Jonah
- Roy Poole - Wells
- Alice Ghostley - Clara
- Bernard Fein - Dasher
- Jan Sterling - Myrtle Tiloff
- Stefan Gierasch - Weller
- Ross Martin - Carlo Ramirez
- James Pritchett - Assignment Board Man
- Louis Guss - Skull
- Louis Guss - Angie
- Joseph Ruskin - 'Count' John Baker
- Abbe Lane - Estelle Reeves
- Mel Ruick - Mr. Harding
- Mel Ruick - Pressfield's Lawyer
- Meg Mundy - Rosalind Winford
- Rochelle Oliver - Cora Gary
- Rochelle Oliver - Katie Harris
- George Mitchell - Al Spangler
- Burt Reynolds - Young Man
- Bruce Gordon - Dr. Sorensteen
- Godfrey Cambridge - Detective Carlisle
- Godfrey Cambridge - George
- Beatrice Straight - Ann Johns
- Jessica Walter - Girl
- Diana Douglas - Meg Peters
- Diana Douglas - Hilda Wallace
- Maureen Stapleton - Abilene Hutchinson Bick
- Maureen Stapleton - Ruth Callan
- Viveca Lindfors - Lulu Kronen
- Constance Ford - Rhonda Cameron
- William Shatner - Maung Tun
- William Shatner - Roger Barmer
- Jeremy Slate - Chuck Mullord
- Arlene Golonka - Alma Corgi
- Arlene Golonka - Carol
- Patrick O'Neal - Roy Pressfield
- Philip Abbott - Charles Alvis
- Philip Abbott - Doctor
- James Tolkan - Evan Humbolt, Mail Clerk
- Frank Sutton - Aces (uncredited)
- Frank Sutton - Franklin Maquon
- Frank Sutton - Marco Butcher
- Dan Duryea - Clyde Royd
- Richard X. Slattery - Police Officer #2
- Richard X. Slattery - Solid
- Ruth Roman - Walda Price
- Fred Clark - Grainger
- Edward Andrews - William Childe
- Eugenie Leontovich - Katina Cretias
- Eugenie Leontovich - Mama Kelle
- Eric Portman - Jayson Condon
- Peter Fonda - Joey Selken
- Rip Torn - Ansel Boake
- Jeanette Nolan - Kate Blake
- J.D. Cannon - Tom Keary
- Aldo Ray - Elvin Rhodes
- Carroll O'Connor - Owen Oliver
- Carroll O'Connor - Tony Corran
- Ruth White - Mama Ganoulian
- Ruth White - Mary Nagler
- Jon Lormer - Minister
- Madeleine Sherwood - Mrs. Wilson
- Madeleine Sherwood - Grace Paraskis
- Piper Laurie - Mary Highmark
- Eduardo Ciannelli - Don Miguel Cordura
- Jean Stapleton - Marilyn Konish
- Jean Stapleton - Mrs. Trellis
- Brandon Maggart - Petty Officer Turnbull
- Brandon Maggart - Mullet
- Michael Strong - Det. Hal Perleman
- Michael Strong - Henry
- David Janssen - Carl Ashland
- David Janssen - Blair Cameron
- Kim Hunter - Edna Daggett
- Eli Wallach - Georgie
- Eli Wallach - Det. Peter Bane
- Salome Jens - Ellen Annis
- Ed Begley - Jimmy Fenton
- Denise Darcel - Madeleine Douvay
- Mildred Natwick - Irma Mahoney
- Barry Newman - Cabby
- Anthony Franciosa - Gorilla
- Gene Hackman - Mr. Jasper
- Robert Webber - Gordon Lanning
- Marisa Pavan - Josephine Scarzi
- Marisa Pavan - Francesca
- Paul O'Keefe - Jack Johannis
- Gretchen Wyler - Ruth
- William Traylor - Melvin Shaw
- Norma Crane - Fay Roberts
- Norma Crane - Lily Braden
- Anthony Zerbe - Philip Karshow
- Arnold Merritt - Jimmy Barrick
- Arnold Merritt - Larry Peters
- Rudy Bond - Lt. Mike Daniels
- Rudy Bond - Lt. Springer
- Conrad Yama - Busboy
- Herb Voland - Charley Bates
- Robert Sterling - Jason Colwell
- Susan Oliver - Jessica Manson
- Herschel Bernardi - Gus Slate
- Herschel Bernardi - Stanley Dorkner
- Dana Elcar - Al Borris
- Doreen Lang - Martha Fallon
- Eli Mintz - Harry Varick
- Burgess Meredith - Duncan Kleist
- Lilia Skala - Valeria Lapesku
- Lilia Skala - Anna Bognar
- Philip Sterling - Officer Schulberg
- Michael Tolan - Peter Merrell
- Michael Tolan - Det. Alan Keller
- Michael Tolan - Ricardo Gardio
- Albert Salmi - Lennard Brewer
- Dick York - Charles Colano
- Orson Bean - Arnold Platt
- Graham Jarvis - Store Manager
- Graham Jarvis - Mr. Denton
- Robert Morse - Richy Wilkin
- Noah Keen - Deputy D.A. Smith
- Chris Gampel - Warden E. A. Darrell
- Joanne Linville - Eunice Vale
- Joanne Linville - Rosie Calageras
- Tom Bosley - Judge
- Frank Campanella - Sergeant Viola
- Frank Campanella - Mr. Capado
- Frank Campanella - Cameraman
- Burt Brinckerhoff - Erwin Lovegod
- Burt Brinckerhoff - Danny Keyling
- Robert Allen - Chief Attorney (uncredited)
- Robert Loggia - Ben Tourelle
- Vincent Gardenia - Crudelli
- Vincent Gardenia - Musso
- Jay Novello - Antonio Scarzi
- Jay Novello - Juan Menguado
- Jay Novello - Gio Bartolo
- Robert Culp - Richard Calder
- Zohra Lampert - Clara Espuella
- Malachi Throne - Hood
- Mike Kellin - Louis Wystemski
- Mike Kellin - Billy Ketch
- Mike Kellin - Anton
- Christopher Walken - Chris Johannis
- Sylvia Miles - Girl In Bar
- Sylvia Miles - Woman #1
- Sylvia Miles - Jenny Barr
- George Voskovec - Jack Selken
- George Voskovec - Prof. Johann von Bunow
- Lily Lodge - Olga
- Edward McNally - Doorman (uncredited)
- Sandy Dennis - Lorraine Kershwood
- Sandy Dennis - Eleanor Ann Hubber
- Alan Alda - Young Poet
- Michael Conrad - Hartog
- Michael Conrad - Pierce
- Michael Conrad - Firing Range Officer (uncredited)
- Ed Asner - Lt. Vincent Busti
- Hy Anzell - Muzzo
- Diahann Carroll - Ruby Jay
- Lincoln Kilpatrick - Bailiff
- Lincoln Kilpatrick - Cappy Fleers
- Naura Hayden - Actress
- Alex Cord - Dick Wilkes
- Alex Cord - Nicholas Kovar
- James Barton - Bo Giles
- James Barton - Matty
- James Barton - Tom Dobbins
- George Maharis - Stroke Strokirch
- George Maharis - Lundy
- George Maharis - Johnny Gary
- George Maharis - Tony Bacallas
- Michael Constantine - Vito Calageras
- Monroe Arnold - Customer's Man
- Irene Dailey - Amy Gary
- Irene Dailey - Auntie Maud
- Keenan Wynn - Maxwell Ronan
- Keenan Wynn - Bodram Borgata
- Peter Helm - Ken Elson
- Ludwig Donath - Owner of Pawnshop
- Ludwig Donath - Stefan
- Ludwig Donath - Doc Randall Benton
- Nina Foch - Maude Hutchinson
- Nina Foch - Kitty Lamson
- James Luisi - Mark Andrew
- Peggy Feury - Tolya Ross
- Anne Helm - Diane
- Michael Shillo - Koersel
- Dustin Hoffman - Lester Stenton
- Dustin Hoffman - Finney
- Edmon Ryan - The Lawyer
- Eddie Albert - Earl Johannis
- Sanford Meisner - Kip Harris
- Shirley Knight - Kathy Meigs
- Joseph Campanella - Detective Dutton
- Joseph Campanella - Dutton
- Joseph Campanella - Dr. Rutland
- Lois Nettleton - Marie Marianni
- Lois Nettleton - Merissa Mori
- Lois Nettleton - Fran Burney
- Lois Nettleton - Sara
- Theodore Bikel - Nicholas Ross / Nicholas Rozinski
- Theodore Bikel - Dr. Stanley Wilford
- Russell Collins - Joseph Peavey
- Candace Hilligoss - Mrs. Harris
- Al Lewis - Gus
- Al Lewis - Mr. Carrari
- Al Lewis - Mr. Pike
- Al Lewis - Mr. Tanner
- Conrad Nagel - Darrington
- Carmine Caridi - Assistant Driver
- Zvee Scooler - Old Aaron
- Mitchell Ryan - Quale
- Mitchell Ryan - Overton
- Mitchell Ryan - Marty Minters
- Mitchell Ryan - Paul Tamarind
- Lou Gilbert - Mr. Green
- Jack Warden - Neil Daggett
- Jack Warden - Steve Lollo
- Jack Warden - Sam Langan
- Peter Falk - Extortionist
- Peter Falk - Frankie O'Hearn
- Peter Falk - Gimpy (uncredited)
- Peter Falk - Lee Staunton
- Louise Platt - Eileen Gerrick
- Albert Dekker - Herbert B. Warick
- Albert Dekker - Samuel Grafton
- Woodrow Parfrey - George Butterwick
- Woodrow Parfrey - Andrew Eisert
- Woodrow Parfrey - Dr. Manning Wirtz
- Geraldine Fitzgerald - Brigid Delito
- Geraldine Fitzgerald - Lillian Clinton
- Mart Hulswit - Ron
- Johnny Seven - Stitch
- Johnny Seven - Carmine Tepperoni
- Johnny Seven - Al Lacey
- Johnny Seven - Biggers
- Johnny Seven - Brick
- Johnny Seven - Paul Colano
- Claudia Morgan - Mrs. Ansted
- Robert Weil - Nesvady
- Robert Weil - Prisoner
- Robert Weil - Happy
- Robert Weil - Betting Man
- Martin Balsam - Arnold Fleischman
- Martin Balsam - Caldwell Wyatt
- Martin Balsam - Captain Russel Barris
- Martin Balsam - Joseph Creeley
- Akim Tamiroff - Emil Pappas
- Akim Tamiroff - Demetru Lapesku
- Jan Norris - Doris Giles
- John Baragrey - Teddy Cochrane
- Sid Raymond - Max (uncredited)
- Sid Raymond - Bartender
- Sid Raymond - Elevator Operator (uncredited)
- Barry Morse - Dr. Paul Multer
- Barry Morse - Art Dealer
- Barry Morse - Professor Ernest Johns
- Murray Hamilton - Matt Orman
- Murray Hamilton - D.A. Thomas Stevenson
- Eugene Roche - Assistant D.A. Smith
- Eugene Roche - George
- Clifton James - George Haskel (uncredited)
- Clifton James - Officer Fennelli
- Clifton James - Jacoby
- Audra Lindley - Sheila Braden
- Audra Lindley - Mrs. Denton
- Audra Lindley - Grace Youngham
- Martin Sheen - Phillip Kosnik
- Martin Sheen - Nick (uncredited)
- Martin Sheen - Counterman
- Bibi Osterwald - Woman Bartender
- Bibi Osterwald - Sylvia
- Bibi Osterwald - Grace
- Alfred Ryder - Link Toland
- Alfred Ryder - Carl Blakely
- Alfred Ryder - John Birge
- Jack Klugman - Alfred Tiloff
- Jack Klugman - Arthur Crews
- Jack Klugman - Pete Kammik
- Jack Klugman - Joe Calageras
- Jack Klugman - Sam Braden
- Jack Klugman - Patrolman Mike Greco
- Paul Richards - Joseph Irona
- Paul Richards - Joseph Highmark
- Susan Melvin - Nancy Bacallas
- Gerald Hiken - Doc Frayley
- Gerald Hiken - Arthur Jarrell
- Louis Sorin - Old Man in Store
- Louis Sorin - Presser
- Leonardo Cimino - Johnny
- Leonardo Cimino - Julio Varraco
- Leonardo Cimino - Miklos Konya
- Leonardo Cimino - Sid Kitka
- Harry Guardino - Johnny Mills
- Harry Guardino - Benvenuto Giovanni
- Kurt Kasznar - Alcibiades Munos
- Kurt Kasznar - Korsica
- Lou Antonio - Al Machias
- Lou Antonio - Ernie
- Lou Antonio - Civil Service Applicant (uncredited)
- Lou Antonio - Charlie Tepperoni
- Joe Silver - Assistant D.A. Ketton
- Joe Silver - Man in Doorway
- Joe Silver - Dean of Admissions
- Tommy Norden - Paul Delito Jr.
- Tommy Norden - Blind Boy #1
- Arnold Soboloff - Waiter
- Arnold Soboloff - Giacovetti
- Arnold Soboloff - Mr. Attuzzi
- Nehemiah Persoff - Max Evar
- Nehemiah Persoff - Merritt Griffin
- Nehemiah Persoff - Barney Peters
- Nehemiah Persoff - Carlos Ruldan
- Nehemiah Persoff - Dominic Venussi
- Nehemiah Persoff - Berco Romanu
- Roger C. Carmel - Fitch
- Roger C. Carmel - Al Buxley
- Roger C. Carmel - Alfred Gurdine
- Roger C. Carmel - Harry Staples
- Roger C. Carmel - Lowell F. Newton
- Roger C. Carmel - Qwist
- Robert Duvall - Lewis Nunda
- Robert Duvall - L. Francis Childe
- Robert Duvall - Barney Sonners
- Robert Duvall - Johnny Meigs
- Walter Matthau - Dr. Max Lewine
- Walter Matthau - Peter Kanopolis
- Jean Muir - Mrs. Klint
- Jean Muir - Mrs. Lund
- Sorrell Booke - Mr. Leventhal
- Sorrell Booke - Salvatore Rogero
- Sorrell Booke - Detective
- Sorrell Booke - Doctor
- Sorrell Booke - Private Detective
- Sorrell Booke - Mr. Hawk
- Sorrell Booke - Uncle George
- Sorrell Booke - Fentus
- Richard Ward - Lee (uncredited)
- Richard Ward - Packer
- Richard Ward - Nova Scotia
- Luther Adler - Sean Wicklow
- Luther Adler - Mr. Kovar
- Luther Adler - Henri Tourelle
- Luther Adler - Willard Manson
- Jan Miner - Superintendent
- Jan Miner - Elsie Knauf
- Jan Miner - Lia Wallace
- Jan Miner - Rosie Wilkin
- Barbara Barrie - Rosalind Faber
- Barbara Barrie - Marcia Kormack
- Barbara Barrie - Sarah Hinson
- Louis Zorich - Manos
- Louis Zorich - Sam
- Eileen Heckart - Mildred Pepper
- Eileen Heckart - Virginia Cort
- John C. Becher - Doctor
- John C. Becher - 2nd Businessman
- John C. Becher - Reporter
- Elizabeth Allen - Laura Lanning
- Elizabeth Allen - Ola Martini
- Elizabeth Allen - Emily Kanopolis
- Doris Rich - Mrs. Sarah Bell
- Doris Rich - Lady in Doorway
- Doris Rich - Mrs. Jassy
- Doris Rich - Mrs. Highmark
- John Larch - John Clinton
- John Larch - Steve Werminski
- John Larch - George Paraskis
- Carol Eve Rossen - Rita Rakahowski
- Carol Eve Rossen - Nancy Hooper
- Carol Eve Rossen - Gladys Hopper
- Charles Dierkop - Registered Mail Clerk (uncredited)
- Charles Dierkop - Hood (uncredited)
- Charles Dierkop - Shushing man at concert (uncredited)
- Charles Dierkop - Boy who Gets Beaten Up (uncredited)
- Charles Dierkop - Hood #1 (uncredited)
- Charles Dierkop - Shag's Friend (uncredited)
- Charles Dierkop - Tow Truck Driver (uncredited)
- Charles Dierkop - Arrest Suspect (uncredited)
- Charles Dierkop - Hungarian in Rail Yard (uncredited)
- Ken Kercheval - Acting Student (uncredited)
- Betty Kean - Mrs. Kelvin
- Neville Brand - Joe Brothers
- Joyce Bulifant - Constance Hacker
- Henry Beckman - Priest (uncredited)
- Nicolas Coster - Civil Service Applicant (uncredited)
- Sharon Farrell - Actress (uncredited)
- Jean Hale - Nurse (uncredited)
- Geoffrey Lumb - Rufus Cates
- Bettye Ackerman - Susan Bognar
- Harold J. Stone - Simon Beecker
- Nancy S. Stone - Diana Doyle
- Robert Emhardt - Wolfgang Krode
- Dabney Coleman - Resident
- Arnold Perl
Johnny Seven interpreta a Carmine Tepperoni en la serie.
Peter Falk interpreta a Frankie O'Hearn en la serie.
James Caan interpreta a Marty Feketi en la serie.
Robert Duvall hace el papel de Barney Sonners.
Sylvia Sidney interpreta a Florence Nunda en la serie.
Claude Rains hace el papel de John Winfield Weston.
Richard Conte hace el papel de Phil Clifford.
Frank Gorshin interpreta a Alan Starkie en la serie.
Gladys Cooper interpreta a Mrs. Ernest Johns, Sr. en la serie.
Robert Redford interpreta a Baldwin Larne en la serie.
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