- David Battley - Mr. Gaunt
- Jake Wood - Derek
- Ken Jones - Mr. Belling
- James Fleet - Tom
- George Costigan - Dave Jones
- Marsha Fitzalan - Lydia's Friend
- Amanda Donohoe - Carmela Vezza
- Dexter Fletcher - Colin
- Tony Slattery - Tony Sparkle
- Alistair McGowan - Marcos
- Peter Serafinowicz - Tony Frost
- Timothy Spall - Pathologist
- Sophie Okonedo - Rachel
- Sarah Lancashire - Karen Sullivan
- Ricco Ross - Gary
- Sara Powell - Staff Nurse Jane
- Martin Marquez - Tony La Paglia
- Caroline Blakiston - Dr. Rachel Vine
- Ray Winstone - Terry
- Jonathan Dow - Gary
- Lucy Benjamin - Katherine
- Paul Putner - Police Constable
- Nigel Havers - Harvey Stafford
- Liam Hess - Rory Phillips
- Hugh Bonneville - Inspector Dawson
- Thelma Barlow - Tiffany's Mother
- Colin Salmon - Lambert
- Ben Miller - P.C. Watkins
- Su Elliot - Deborah Case
- Norman Eshley - DCI Reed
- Chris Langham - Harry
- James Callis - Mark
- Richard Braine - Rev. Stoop
- Patricia Hayes - Mrs. Templecombe
- Jim Broadbent - Selwyn Proops
- John Fortune - Squire Thorpe
- David Harewood - Jonathon
- Brian Capron - Chris Bastable
- Robert Llewellyn - Taxi Driver
- Stratford Johns - Mr. Maddox
- John Bird - Duncan Jupp
- Hywel Bennett - Clancy
- James Cossins - Sir Hugh Lotterby
- Gary Love - Constable Williams
- Jane Asher - Lydia Howling
- Kim Wall - Yacht Salesman
- Stephen Moore - Basil Hampton
- Pip Torrens - News Presenter
- Angela Wynter - Hotel Receptionist
- Brigit Forsyth - Mrs. Osman
- Georgina Hale - Lady Jamieson
- Kathy Burke - Helen
- Danny Webb - Tony Smedley
- David Bamber - Ray
- Clive Russell - DCS Barratt
- Richard Johnson - Rev. Charles Quentin
- Bill Paterson - Chief Inspector
- Jamie Foreman - DS Brown
- Roger Lloyd Pack - Frank Foster
- Clarke Peters - American
- Ricky Grover - Barman
- Martin Jarvis - Maurice Howling
- Peter Vaughan - Doverson
- Timothy West - Old Doctor Adams
- Hugh Laurie - Jerry Bryce
- Julie Peasgood - Waitress
- John Thomson - Daniel Hoffmeyer
- Toby Longworth - Estate Agent
- Stephen Frost - Sgt. Dawkins
- Peter Wingfield - Giles
- Paul Reynolds - David Flint
- John Bennett - DCI Graham Barlow
- Minnie Driver - Sgt. Cole
- James Saxon - Young Adams
- John Boswall - Judge
- Bryan Pringle - Mr. Franklin
- Michael Elphick - Bill Todd
- Sean Hughes - Zack Mitchell
- Philip Jackson - Police Sergeant
- Philip Jackson - Patron
- Llewella Gideon - Sister Debbie
- Tom Szekeres - Rollo Bogleby
- Kenneth Cranham - Inspector Salford
- Martha Cope - Andrea
- Steve Speirs - DI Hooper
- Helen Lederer - Yvonne Quail
- Kevin McNally - Inspector Turner
- Kevin McNally - Mr. Bogleby
- Jonathan Cecil - Mr. Warburton
- Philip Martin Brown - Psycho
- Tres Hanley - Stewardess
- Mark McGann - Tommy
- Marcus D'Amico - Raul Manendez
- Togo Igawa - Japanese Tourist
- Alan Ford - First villain
- Kevin Allen - Simon Pleasance
- Kevin Allen - Driver
- Gwen Taylor - Beryl
- Brian McCardie - Supermarket Assistant
- Victoria Wicks - Jocasta
- John Benfield - Barry Todd
- Richard Hansell - Gerry
- Harriet Thorpe - Sarah Deveraux
- Harriet Thorpe - Friend
- Robert Pugh - DI Morgan
- Jonathan Coy - Benjamin Trethansis
- Jim Carter - Roy Redfern
- Jim Carter - General Alberto
- Joanna Scanlan - Iris Wood-Newton
- Patrick Toomey - Reporter
- Christopher Adamson - Mikey Perugiano
- Ron Berglas - Louie Finkel
- Lorna Brown - Woman in Office
- Sean Gallagher - Sean Lacey
- Frances Barber - Gloria Twigge
- Graeme Garden - Alex Docherty
- Mark Chapman - Security Man
- Mark Chapman - DC Finch
- Peter Bland - Editor
- Paul Mark Elliott - Max Rammell
- Michael Sharvell-Martin - Mayor
- June Ellis - Woman on Bus
- Kate Williams - Woman on Bus
- Soo Drouet - Bus Conductress
- David Barber - Boy on Bus
- Henry Naylor - Journalist
- Geoffrey McGivern - Mason
- Christopher Good - Leonard
- Jacey Sallés - Silvia
- Georgine Anderson - Mrs. Stewart
- Jon Plowman
- Peter Fincham
Michael Elphick hace el papel de Bill Todd.
Sophie Okonedo interpreta a Rachel en la serie.
Alan Ford interpreta a First villain en la serie.
Peter Vaughan interpreta a Doverson en la serie.
Jim Broadbent interpreta a Selwyn Proops en la serie.
Kevin McNally interpreta a Mr. Bogleby en la serie.
David Battley hace el papel de Mr. Gaunt.
Dexter Fletcher interpreta a Colin en la serie.
Jamie Foreman interpreta a DS Brown en la serie.
Dawn French interpreta a Various characters en la serie.
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