- Makenzie Leigh - Addison
- Chloe Fineman - Fanny Mendelssohn
- Bob Dishy - Bruno
- Gabriel Millman - Drunk Boy
- Rachel Zeiger-Haag - Drunk Girl
- Eddie K. Robinson - Party Guy #1
- Kaitlin Mesh - Dancer #3
- Katie Webber - Dancer #6
- Samuel Stricklen - Violinist
- Raymond McAnally - Percussionist
- Constantine Maroulis - Oedipus / Constantine
- Constantine Maroulis - Oedipus
- David Shih - Pianist
- Brenna Palughi - Threesome Woman
- James E. Graseck - Homeless Violinist
- Jerry Adler - Lazlo
- Annie McNamara - Cathy
- Cicily Daniels - Clerk
- Amirah Vann - Nurse
- Ian Joseph Paget - Alex Dance Double
- Alan Aisenberg - Sidney
- Michael Braun - Robert
- Beth Dixon - Older Woman 1
- Joanna Bonaro - Maria
- Liam Craig - Priest
- Greg McFadden - Producer
- Samantha Sherman - Box Office Lady
- Samuel Ray Gates - Spiritualist
- Keith Poulson - Derrick
- Kevin Michael Murphy - Stunt Thief
- Aly Mang - Bartender (uncredited)
- Daniel Raymont - Emanuel Oosthuizen
- Griffin Birney - Duncan
- Nashawn Kearse - Neighbor
- Nashawn Kearse - Loud Neighbor
- Michael Devine - Officer #2
- Brendan Titley - Bartender
- Frank Rodriguez - Limo Driver
- Frank Rodriguez - Town Car Driver
- Manuel Cabral - Man in Window
- Ekaterina Samsonov - Alice
- Diane Kagan - Winifred
- David Ross - Valet
- Doris McCarthy - The Crinkler (uncredited)
- Doris McCarthy - Nun (uncredited)
- Doris McCarthy - Upscale Gala Guest (uncredited)
- Susan Blommaert - Karla
- Constance Barron - Society Woman
- Logan Riley Bruner - Kid #2
- Erica Newhouse - Stylish Woman
- Phil Oddo - Party Guest (uncredited)
- Rufus Collins - Psychiatrist
- Mckean Rand - Evan
- Mike Massimino - Security Guard
- Steve Mellor - Hotel Clerk
- Ayumi Patterson - Benita
- Ivo Velon - Jean-Luc (uncredited)
- John Hodgman - Marlon
- Kathleen Butler - Elisabeth Meriweather
- Gustavo Dudamel - Stage Manager
- Christopher Marquette - Mozart
- Mary Shultz - Donor Woman 1
- Mary Shultz - Older Woman 3
- Mary Shultz - Arlene Bluenstruth
- Michael D. Joseph - Restaurant Patron (uncredited)
- Margaret Ladd - Claire
- Margaret Ladd - Claire Pembridge
- Adam Enright - Naked Performance Artist
- Anton Coppola - Anton Gallo
- Lee Shepherd - Mr. Hamburg
- Max Chernin - Jazz Hander
- Paul Romero - Heart Attack Guy
- Lang Lang - Lang Lang
- Emanuel Ax - Emanuel Ax
- Alan Gilbert - Alan Gilbert
- Henry Stram - Process Server
- Sofía Sisniega - Cocktail Waitress
- Gabriel Pingarrón - Erasmus
- Maya Zapata - Paula
- Gimena Gómez - Anita
- Amelia Zapata - Paula's Mom
- Esai Morales - Juan Delgado
- Ana Ofelia Murguía - Nana Graciela
- Yolanda Abbud L. - Aunt Lola
- Nancy Cejari - Concert Attendee (uncredited)
- Nancy Cejari - Business Woman (uncredited)
- Myrna Cabello - Lead Handler
- Jos Laniado - Spectator (uncredited)
- Jos Laniado - Community Member #1
- Patrick Husted - Priest
- Deborah Finley - Nun (uncredited)
- Luke Rampersad - Lennox
- Charles Fleischer - Dr. Tashoff
- Brian d'Arcy James - Ludwig van Beethoven
- Anais Lee - Kid 2
- Ana Cecilia Stieglitz - Flight Attendant (uncredited)
- Ana Cecilia Stieglitz - Flight Attendant
- Dante Pereira-Olson - 5 Year Old Bradford (voice)
- Zack Robidas - Bradford's Dad (voice)
- Sophie Auster - Gabrielle
- Michael Crane - Man
- Dean Neistat - Mounted Policeman
- Danielle M. Williamson - Student with Backpack (uncredited)
- James Rutledge - Board Member
- Doug Yasuda - Orchestra Member 1
- Christine Toy Johnson - Orchestra Member 2
- Brandon S. Martinez - Ball Kid
- Maeve McGuire - Board Member
- Julia Effertz - Musician (uncredited)
- Logan Fry - Concert Spectator in Tuxedo (uncredited)
- Wayne J. Miller - Musician (uncredited)
- Prima Apollinaare - Wilhemina
- Daria Pascal Attolini - Carlita
- Alan Cappelli Goetz - Mime
- Kangmin Justin Kim - Impersonator
- Aaron Moten - Erik Winkelstrauss
- Aaron Moten - Erik Winkelstrauss (uncredited)
- Rita Duran - Rocker (uncredited)
- Rosaria D'Urso - Francesca
- Lucia Guzzardi - Annunziata
- Nico Muhly - Nico Muhly
- Ken Barnett - Christophe
- Ken Barnett - Rick
- Tenoch Huerta Mejía - Manuel
- Tenoch Huerta Mejía - Manu
- Danny Glover - Mayor
- Elisabetta Bonino - Saleswoman
- Alessandro Bressanello - Lionel
- Kristin Mercedes Bence - EDM Dancer / Fan (uncredited)
- Andrea Bruschi - Vlad
- Antonio Pauletta - Orchestra Translator
- Sonia Villani - Anika
- Andrea Dugoni - Parlotti the Critic
- Andrea Dugoni - Parlotti
- Emilio Echevarría - Maestro Ignacio Rivera
- Monica Bellucci - Alessandra
- Christian De Sica - Impresario Beppi
- Daniele Blando - Head of Claque
- Giovanni Silvestrini - Audience in Venice (uncredited)
- Paolo Braghetto - Fotografo (uncredited)
- Plácido Domingo - Plácido Domingo
- Ruibo Qian - Triangle Tanya
- Brennan Brown - Edward Biben
- Gretchen Mol - Nina Robertson
- Andrew Elvis Miller - Lars
- Andrew Elvis Miller - Lars (uncredited)
- Dermot Mulroney - Andrew Walsh
- Amos VanderPoel - VR Stage Manager
- Charlie Moss - Russian Conductor
- Seth Barrish - Roger Colson
- Bernard Uzan - French Conductor
- Marisa Brau-Reyes - Perky Receptionist
- Thomas Schall - German Conductor
- Joshua Bell - Joshua Bell
- Adam David Thompson - Craig G
- Daniel Breaker - Virgil
- Jason Schwartzman - Bradford Sharpe
- Eli Bridges - Street Musician
- John C. Vennema - Older Man / Christophe's Dad
- Marie Smalley - Orchestra Management (uncredited)
- Irene Choi - Ester Park
- Ronald Guttman - Bach
- Chip Zien - Larry the Night Watchman
- Baron Davis - Kevin Majors
- Susan Coyne - Lily Cramer
- Viola Harris - Kay Windsor
- Jerry Matz - Leslie Windsor
- Maria-Christina Oliveras - Linda
- John Rue - Doctor
- Prema Cruz - Sara Kazmir
- Teodorina Bello - Elida
- Nico Bustamante - Jordan
- Vít Hořejš - Czech Puppeteer
- Jason Shelton - Lizzie's Server
- Anna Suzuki - Terry the Stage Manager
- Thorgy Thor - Thorgy Thor
- Ana Villafañe - Rodrigo's Wife
- Teddy Coluca - Diner
- Caleb Eberhardt - Ferndale Musician
- Linda Powell - Mrs. Kolb
- J. Smith-Cameron - Amy Rutledge
- Jenna Qureshi - Rachel
- Miles Robbins - Danny / Erase Face
- Miles Robbins - Eraseface
- Miles Robbins - Erase Face
- Terri Weagant - Coordinator
- Adina Verson - Maria Anna Mozart
- Adina Verson - Nannerl
- Sissy Sheridan - Hailey's Music Classmate (uncredited)
- Mary Louise Wilson - Bunny
- Christine Chang - Japanese Waiter
- Caroline Shaw - Caroline Shaw
- Frank Wood - Keith Rutledge
- Frank Wood - Keith
- Ross Brodar - Biker
- Shannon Plumb - Isabella Leonarda
- Dean Ciallella - Party Guest (uncredited)
- Bryce Lorenzo - Janelle (uncredited)
- Wallace Shawn - Winslow Elliott
- Grasan Kingsberry - Ben
- George Aloi - Arnar (uncredited)
- Shusaku Kakizawa - Music Critic
- Masa Kokubo - Patron (Cultist)
- Nozomi de Lencquesaing - Phillippe (uncredited)
- ??? - Daisuke Ueno
- ????? - Sadako
- ???? - Takashi
- Will Graham - WAM (voice)
- ????? - Noburo
- ???? - Hedgehog Café Waitress
- Nora Arnezeder - Ana Maria
- Masaki Naito - Rodrigo Fanatic
- Yuki Shibamoto - Judge's Assistant #1
- Yasunari Takeshima - Tateo
- Jennifer Kim - Sharon
- Joan Jett - Joan Jett
- Michael Emerson - Morton Norton
- Ramsey Faragallah - Daniel Mahajan
- Pablo Heras-Casado - Pablo Heras-Casado
- Raymond Lee - Arlen
- Matthew Maher - Alan Lawford
- Kristen Faith Oei - Dancer #3
- Karine Plantadit - Dancer #1
- Bradley Gibson - Ballet Team Capt
- Mark Blum - Union Bob
- Debra Monk - Betty Cragdale
- Joel Bernstein - Warren Boyd
- Santino Fontana - Mozart
- Christian Coulson - Sebastian
- John Cameron Mitchell - Egon
- Masi Oka - Fukumoto
- Bruce Davison - Hesby Ennis
- Kevin Cano - Soccer Player
- Cole Escola - Shawn
- Drena De Niro - Carmen
- Marion McCorry - Cat Lady
- Peter Vack - Alex Merriweather
- Socorro Santiago - Rosa
- Roman Coppola
- Paul Weitz
- Jason Schwartzman
Emilio Echevarría interpreta a Maestro Ignacio Rivera en la serie.
Michael Emerson hace el papel de Morton Norton.
Susan Blommaert interpreta a Karla en la serie.
Danny Glover interpreta a Mayor en la serie.
Gael García Bernal interpreta a Rodrigo De Souza en la serie.
Lola Kirke hace el papel de Hailey Rutledge.
Saffron Burrows interpreta a Cynthia Taylor en la serie.
Bernadette Peters interpreta a Gloria Windsor en la serie.
Malcolm McDowell interpreta a Thomas Pembridge en la serie.
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