- Ed Boon - Ed Goodman
- David Nykl - Lance
- Adrian Hough - Emile
- Erica Cerra - Action Star
- Victor Lucas - self
- Brian Goodman - Brian Himmerick
- Elysia Rotaru - Production Assistant
- Aaron Au - Gang Member #1
- Chad Bellamy - Gang Member #2
- Simon Burnett - Gang Member #3
- Yves Cameron - Gang Member #4
- Paul Lazenby - Studio Security Guard #1
- Darryl Quon - Studio Security Guard #2
- Deena Dill - Johnny Cage's Girlfriend (uncredited)
- Tahmoh Penikett - Lt. Kurtis Stryker
- Colin Corrigan - Technician #1
- Matt Reimer - SWAT
- Brett Chan - SWAT
- Phillip Mitchell - SWAT
- Kim Do Nguyen - Black Dragon
- Nestor de la Zerda - SWAT (uncredited)
- Lani Gelera - Edenian Woman
- Colin Decker - Edenian #1
- Eli Zagoudakis - Edenian #2
- Beatrice King - Queen Sindel (archive footage)
- Beatrice King - Queen Sindel
- Don Lew - Tarkatan Warrior
- Aleks Paunovic - Shao Kahn
- Jolene Tran - Mileena
- Kirby Morrow - King Jerrod
- Karin Inghammar - Narrator (voice)
- Fraser Aitcheson - Baraka (archive footage)
- Aaron Hutchinson - Edenian Knight #1
- Andrew Chin - SWAT
- Andrew Chin - Thug #1
- Ryan Robbins - Raiden
- Tracy Spiridakos - Blue
- Johnson Phan - Shang Tsung
- Johnson Phan - Shang Tsung (archive footage)
- Peter Hall - Dr. Gadsen
- Lauro David Chartrand-DelValle - White Coat #1
- Sylvesta Stuart - White Coat #2
- Larnell Stovall - White Coat #3
- Kevan Ohtsji - Sub-Zero / Narrator
- Brandon Nomura - Jubei
- Michael J Rogers - Quan Chi
- Shane Warren Jones - Cyrax / Hydro
- Peter Shinkoda - Sektor
- Serge Houde - Doctor
- Colin Foo - Grand Master
- Brooke Graeff - Computer (voice)
- Shaun Balbar - Technician #2
- James Bamford - Thug #2
- Masayuki Yonezawa - Karaoke Drunk
- Phoenix Wong - Bartender
- Sam Looc - Loudmouth Drunk
- Mark Musashi - Asian Gangster
- Remington Hoffman - Bi Han's Father
- Maurissa Tancharoen - Kana
- Karen Teliha - Waitress
- Tiago Roberts - Police Officer
- Koji Kataoka - Onmyoji
- Y.J. Gold - Lieutenant
- Stephen Oyoung - Tattoo Gangster
- Kerry Wong - Triad
- Dan Southworth - Kenshi
- David Lee McInnis - Raiden
- Michelle Lee - Mileena
- Harry Shum Jr. - Kuai Liang
- Ethan Josh Lee - Young Hanzo Hasashi
- David Kim - Lin Kuei Clansman
- David Kim - Lin Kuei Guard
- Forrest Wheeler - Young Kuai Liang
- Masami Kosaka - Hanzo's Father
- Jonathan Erickson Eisley - Gunman #1
- Bryan Thompson - Gunman #2
- Brian Tee - Liu Kang
- Mark Dacascos - Kung Lao
- Eric Jacobus - Kurtis Stryker
- Cary-Hiroyuki Tagawa - Shang Tsung
- Jon Komp Shin - Shirai Ryu (uncredited)
- Jeri Ryan - Sonya Blade
- Michael Jai White - Major Jackson 'Jax' Briggs
- Eric Steinberg - Bi Han / Sub Zero
- John Lewis - The Boss
- Brian Fong - Old Man
- Caroline Tudor - Mollee
- Kevin Tancharoen
David Nykl interpreta a Lance en la serie.
Adrian Hough interpreta a Emile en la serie.
Erica Cerra interpreta a Action Star en la serie.
Brian Goodman interpreta a Brian Himmerick en la serie.
Elysia Rotaru hace el papel de Production Assistant.
Aaron Au interpreta a Gang Member #1 en la serie.
Chad Bellamy interpreta a Gang Member #2 en la serie.
Simon Burnett interpreta a Gang Member #3 en la serie.
Paul Lazenby interpreta a Studio Security Guard #1 en la serie.
Darryl Quon interpreta a Studio Security Guard #2 en la serie.
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