- Vanessa Lengies - Leni Hayes
- Victor Webster - Owen Haggans
- Sarah Tareen - Audrey
- Alice Greczyn - Sam
- Justice Leak - Ray Fordham
- Shelbie Bruce - Nicole
- Victoria Pratt - Dee Dee Dwight
- Lil' Zane - Clint
- Roy Vongtama - Morgue Attendant.
- Jermaine Williams - Phil
- Jason Butler Harner - Lane
- Claudia Black - The Cleaner
- Rachel Kimsey - Eileen Hannigan
- Molly Culver - The Cleaner
- Derk Cheetwood - Kevin Branch
- Gideon Emery - Donovan Shepard
- Ian Abercrombie - Richard Whitley
- Holly Valance - Lola
- Rudolf Martin - Christian Ellis
- Emilio Rivera - Chemma Tejada
- Richard Cox - Richard Haggans
- Edoardo Ballerini - Pierce Anders
- Anthony Starke - Ken Verdolino
- Eddie McClintock - Jason Abbot
- Elizabeth Tulloch - Celeste
- Patrick Fischler - Alan
- Jacob Vargas - Guillermo
- David Blue - Logan Griffen
- Meredith Monroe - Cynthia
- Greg Pitts - Grant Lewis
- Mark Totty - Jerry Drake
- Bonnie Root - Ellen
- Bonnie Burroughs - Julie Fordham
- Brian J. White - Lt. Carl Davis
- Gigi Rice - Martha
- Lisa Sheridan - Julia Stephens
- Christopher Cousins - Kent Morrow.
- Kevin Weisman - Steve Blafour
- Kevin Weisman - Steve Balfour
- Mark D. Espinoza - Father Garza
- Margaret Easley - Dr. Alison Lin
- Chris Payne Gilbert - Dr. Jeff Pollack
- Abigail Spencer - Simone Walker
- Dean O'Gorman - Daniel
- Maurice Compte - Bustos
- Brad Greenquist - Gerald Stovsky
- Erika Schaefer - Lisa
- Hal Williams - 70-Year-Old Det. Bobby Desmond
- Eric Winter - ADA Benjamin Talbot
- Heather Stephens - Emma Monaghan
- Jonathan LaPaglia - Jackson Monaghan
- William Christian - Ryan Gold
- Peyton List - Tierney Taylor
- Jill Latiano Howerton - The Cleaner
- Daniel Goldman - Jacob
- Amro Salama - Scientist
- Josh Wingate - 20-Year-Old Lee Jay Spalding
- David Fabrizio - 40-Year-Old Lee Jay Spalding
- Lawrence Mandley - 40-Year-Old Det. Bobby Desmond
- Brian Oerly - Cam
- Jon Jon Briones - Party Goer
- Catherine Kresge - Reporter #1
- Kevin T. McCarthy - Reporter #2
- Cosimo Canale - Ricardo
- Jordan Belfi - Josh Lindsey
- Countrified Wedman - David
- Josh Clark - Ed
- Diego Villarreal Garcia - Clerk
- Cate Cohen - Randi
- Jared Farid Ward - Doctor #1
- Tiya Sircar - Doctor #2
- Navid Negahban - Amir Fayed
- Philip Maurice Hayes - Colden
- James C. Victor - Kempner
- Haley Pullos - Mara
- Martez Covington - Omar
- Tami Roman - Maureen
- Wes Robinson - Mineo
- Casey LaBow - Cherish
- Christine Romeo - Mom
- Tom Ohmer - Dad
- Nate Mooney - Rider England
- Janelle Marra - Janelle Giumarra
- Deanna Smith - Natalie
- Asia De Marcos - Fed #1
- David Haley - Fed #2
- Anil Raman - Terrance
- Josh Kelly - Calvin
- Adam Shapiro - Attendant
- Michelle Lee - Black Crystal Girl
- Brian Maillard - Bandmate #1
- Rhomeyn Johnson - Fire Inspector
- Quincy Newton - Levi
- Alicia Randolph - Young Audrey
- Lorena Segura York - Bronwyn
- Aisha Kabia - Miriam
- Christopher Guyton - Phillips
- Kathleen Munroe - Tina Haggans
- Marc Anthony Samuel - Tucker
- Andrew Wei Lin - Waiter
- Nick E. Tarabay - Ralf Martan
- Paul Rae - Tom
- Kavita Patil - Doctor Duffy
- Rashawn Underdue - Tim
- Al Galvez - Dan
- Elizabeth Chambers - Victoria's Secret Model
- Greg Allan Martin - Older Man
- Jane Galloway Heitz - Elderly Woman
- Betty A. Bridges - Paula
- Edward Carnevale - Doorman
- Manuel Urrego - Jorge Perez
- Jon Emm - Judge
- Luis Moncada - Huerta
- Jeremy Denzlinger - Paramedic
- Christopher Stapleton - Officer
- Lonnie Hughes - Clarence Brown
- Charley Rossman - Security Guard
- Jeremy Forte - Scientist
- Tasha Tae - Hostess
- Marques Johnson - Minister
- Ksenia Solo - Bonnie Morrow
- Amy Motta - Interior Designer
- Alex Sol - Dean
- Sean Wing - Scott Walsh
- Martin Spanjers - Marshall
- Marc Vahanian - Partygoer #2
- Bryan Rasmussen - Paparazzo #1
- Robert Okumu - Paparazzo #2
- Robin Thomas - Robert Fordham
- Mercedes Connor - Lilah Fordham
- Christian Keyes - Dominic Brewer
- Erika Ringor - Det. Theresa Novak
- Ryan Caltagirone - Hank Bishop
- Todd Giebenhain - Leo
- Matt Riedy - Hearst College Chancellor
- Vince Pavia - Guard
- Mitch Eakins - Troy
- Jacleen Haber - Cleaner #4
- Eduardo Ortiz - Stu Peldon
- Eduardo Ortiz - David
- Stephen Jackson - Hank
- Robert Noble - Toupee Man (uncredited)
- Jennifer Chu - Architect
- Rod Holcomb
- Trevor Munson
- Joel Silver
- Chip Johannessen
- Gabrielle Stanton
- Harry Werksman
Alex Sol interpreta a Dean en la serie.
Rade Šerbedžija interpreta a Josef Kostan en la serie.
Alex O'Loughlin interpreta a Mick St. John en la serie.
Sophia Myles hace el papel de Beth Turner.
Jason Dohring interpreta a Josef Kostan en la serie.
Shannyn Sossamon hace el papel de Coraline Duvall.
Capítulo disponible en las siguientes plataformas:
