- John Ortiz - Rogelio 'Ro' Burton
- Todd Allen Durkin - Sheriff Sonny Summers
- Matt Shively - James Mayberry
- Charlotte McKee - Louisa Mayberry
- Jacob Daniel Smith - Willy
- Lauren Buglioli - Heather
- Brett Cormier - Charles Phinney
- Lily Jane - Natalia
- Tyler Picchi - Simon
- Terry Allen Jones - Mr. Knowles
- Jeffery S. Herman - Dr. Clifford Witt
- Dwayne Alistair Thomas - Charles
- Demi Castro - Fed
- Victor Turpin - Montenegro
- David St. Louis - Egg
- Brian Thomas Smith - Brennan
- Gizel Jimenez - Mel Campesino
- Roberto Escobar - Mateo Campesino
- Reese Antoinette - Dawnie
- Aba Arthur - Samara
- Madelin Marchant - Ines Campesino
- Ali Macaulay - Hostess
- Adam Ignacio - Gardener
- Nadia Adelay - Bay's Edge Host
- CC Crain - Mel's Friend
- Jeremy King - Brad
- James D. Ballard - Dr. Dineen
- Crystal the Monkey - Driggs
- Zach Braff - Israel 'Izzy' O'Peele
- Gonzalo Menendez - Mendez
- Krys Marshall - Tanny
- Tom Hillmann - Buzz
- Amina Massai - Lulu
- Anthony Belevtsov - Pestov
- Tony Bentley - Murphy
- Tyler Colfer - Donald
- Ed Berliner - Gene
- Aaron Goldenberg - Co-Worker
- Anmalya Delva - Andrea Wendell
- Scott Glenn - Jim Yancy
- Arian S. Cartaya - Sam O'Peele
- Austin Janowsky - Officiant
- Rachel Comeau - Marisol O'Peele
- Veasna Keo - Robber
- Ricky Wayne - Dennis Chance
- William Ngo - Officer
- Zach Lane - Aidan
- Brian Brightman - Suit
- Gregg Weiner - Other Suit
- Laura Ault - Kyra Brown
- Adrian Tristan - Newscaster
- Tom Nowicki - Captain Keith Fitzpatrick / Narrator
- Bob Clendenin - K.J. Claspers
- Alex MacNicoll - Cody
- Timothy Mark Davis - Scott
- Hunter Romanillos - Jorge
- Autumn Monroe - Ms. Cay
- Hardy Rawls - Groundskeeper
- Xander Mateo - Benito
- Jack Covington III - Cop
- Alex Livinalli - Drug Runner
- Camila Rodríguez - Paula
- Austin Lampe - Thom
- Lauren O'Quinn - Director Rhodes
- Lawrence H. Collins - Craig
- Meggie Cherilus - Gracie's Mother
- Meggie Cherilus - Young Woman
- Shawn Reimer - Cashier
- John Menchion - Andre the Bartender
- Jeff Chase - Russian Behemoth
- Derek Russo - Russian Goon
- Avery Sommers - Mrs. Martin
- Essex O'Brien - Airport Worker
- Nicolas Sellar - Tomas
- Garfield Wedderburn - Bacon
- Alejandro Guevarez - Pilot
- Carl Hiaasen
- Jeff Ingold
- Vince Vaughn
- Bill Lawrence
- Liza Katzer
- Matt Tarses
Michelle Monaghan interpreta a Bonnie en la serie.
Jodie Turner-Smith interpreta a Dragon Queen / Gracie en la serie.
Meredith Hagner hace el papel de Eve.
Rob Delaney hace el papel de Christopher.
Natalie Martinez interpreta a Rosa en la serie.
L. Scott Caldwell interpreta a YaYa en la serie.
Ronald Peet interpreta a Neville en la serie.
John Ortiz interpreta a Detective Rogelio en la serie.
Capítulo disponible en las siguientes plataformas:
