- Sadie Calvano - Violet Plunkett
- Matt Jones - Baxter
- French Stewart - Chef Rudy
- Beth Hall - Wendy Harris
- Beth Hall - Janice
- David de Lautour - Greg
- Robert Curtis Brown - Edward
- Jon Cryer - Customer
- Shane Blades - William
- Kristen O'Meara - Dolores
- Justin Long - Adam
- Dorian Brown Pham - Betsy
- Aubyn Philabaum - Lisa
- Jim Holmes - Wayne
- Matt Cook - Geoff
- Christopher Darga - Customs Agent
- Octavia Spencer - Regina Tompkins
- Nick Searcy - Nathan
- Lauren Bowles - Mary
- Robb Derringer - Vic
- Victoria Oscar - Woman
- Stacey Moseley - Customer
- Matt Roth - Jerry
- Peter Porte - Dr. Huss
- Bob Stephenson - Edward
- Nick Zano - David
- Tiffany Dupont - Alicia
- Jim Jansen - Judge Dugan
- Bob Glouberman - Mr. Davenport
- Brian Stepanek - Fred
- Rizwan Manji - Dr. Bellin
- Sloane Avery - Mindy
- Alex Désert - Wes
- Ryan Cartwright - Jeff
- Melissa Tang - Suzanne
- Regi Davis - Manager
- Molly Hawkey - Woman
- Wayne Wilderson - Dr. Butler
- Ericka Kreutz - Emma
- Stacy Arnell - Gail
- Zylan Brooks - Donna
- Jim Hanna - George
- Daniel Steven Gonzalez - Swat Officer
- Andrew Tinpo Lee - Dan
- Crista Flanagan - Beth
- Richard Riehle - John
- Brigitte Kali Canales - Isobel
- Art Bonilla - Ricardo
- James Earl - Dudley
- Meredith Giangrande - Andrea
- Jim Piddock - Kenneth
- Ed Asner - Jack
- Rick Fox - James
- Stefan Marks - Guy
- Dana Powell - Jessica
- Brandon Morales - Tony
- Ellen Burstyn - Shirley
- Duane R. Shepard Sr. - Al
- Chris Erric Maddox - Steve
- Carol Herman - Ethel
- Jill Lover - Carla
- Kotaro Watanabe - Dr. Nakamura
- Judy Greer - Michelle
- Emily Osment - Jodi
- Sonya Eddy - Angela
- Daisy Galvis - Woman
- David Krumholtz - Gregory
- Sonia Jackson - Janet
- David Ury - Randy
- Marcus Folmar - Fireman #2
- Ron Roggé - Fireman #3
- Noah Thorne - Cheff
- Mark Saul - Cooper
- Carmella Riley - Megan
- Lewis T. Powell - Paramedic
- Beverly D'Angelo - Lorraine
- Ian Reed Kesler - Lee
- Colin Hanks - Andy
- Kiva Jump - Carla
- Alan Rachins - Jed
- Juan Alfonso - Officer Barry
- Clark Duke - Jackie
- Christopher Nicholas Smith - Douglas
- Rachel Germaine - Rebecca
- Teddy Vincent - Woman #2
- Teddy Vincent - Woman #4
- Toby Huss - Bill
- April Bowlby - Selene
- Max Daniels - Lenny
- Meg Chambers Steedle - Shelly
- David Barrera - Gary
- Julie Dretzin - Wendy
- Seth Coltan - Andrew
- Stacy Hall - Mitch
- Ariel Meislin - Tenant #1
- Cory Jacob - Tenant #2
- John Charles Meyer - Jesus
- Victor Webster - Dr. Harris
- Michael Croner - Cliff
- Matt Hobby - Chip
- Mark Adair-Rios - Dr. Gonzalez
- Llou Johnson - Vial (voice)
- Fred Tatasciore - Canister (voice)
- Tom Amandes - Richard
- Brenda Ballard - Old Woman
- Kelly Stables - Kathy
- Nick Bakay - Man on Tape (voice)
- Nick Bakay - Man (voice)
- Michelle N. Carter - Tracy
- Anzu Lawson - Luanne
- Van Epperson - Judge
- Kim Yarbrough - Bailiff
- June Squibb - Dottie
- Meghan Maureen McDonough - Tina
- Tricia O'Kelley - Mrs. Lippert
- Lamont Thompson - Marcus
- Daniel Montgomery - Andre
- Shawn Parikh - Craig
- Harry Hamlin - Fred
- Alec Mapa - Milo
- Joe Dietl - Larry
- Monica Garcia Pérez - Soledad
- Israel Sáez de Miguel - Antonio
- Jeremy Long - Gay AA Member
- Joe Manganiello - Julian
- Jean St. James - Tricia
- Rhea Perlman - Anya
- Tom Mardirosian - Priest
- David Mattey - Pierre
- Senyo Amoaku - Officer Craig
- Gary Kraus - Officer Ted
- Dave Fennoy - Narrator (voice)
- Alison La Placa - Louanne
- Sean T. Krishnan - Dr. Patel
- David Figlioli - Andre
- Michelle La - Dakota Nakatumi
- Kevin Fonteyne - Danny
- Aris Alvarado - Al
- David Meunier - Yuri
- Michael Canetty - Vern
- Kathleen Turner - Cookie
- Bradley Whitford - Mitch
- Kate Micucci - Patty
- Tracy Vilar - Lorraine
- Ted McGinley - Dr. Berenson
- George Paez - Ramone
- Courtney Thorne-Smith - Sam
- Missi Pyle - Natasha
- Parisa Fakhri - Laurie
- Michanne Quinney - Hostess
- Jane Carr - Betty
- Kevin Dunn - Gary
- Danny Brown - Cassie
- Tom Virtue - Waiter
- Mark Berry - Douglas
- Nicole J. Butler - Woman #1
- Raymond Ma - Husband
- Katherine Von Till - Dixie (voice)
- Peter Banifaz - Old Roscoe
- Verona Blue - Menacing Woman
- Tim Trobec - Immigration Officer #2
- David Ghilardi - Immigration Officer #3
- Johnny Kostrey - Immigration Officer #4
- Patrick O'Connor - Minister
- Courtney Henggeler - Claudia
- Rodney J. Hobbs - Waiter
- Jim Pirri - Italian Language Instructor (voice)
- Monti Washington - Bernard
- Bonnie Hellman - Barbara
- Wylie Small - Woman
- Jesse Luken - Travis
- Steven Boyer - Dave
- Susan Leslie - Wife
- Richard Schiff - Robert
- Stacey Travis - Deborah
- Linda Lavin - Phyllis
- Artt Butler - Male Voice (voice)
- Artt Butler - TV Announcer (voice)
- Nick Toth - Richard Pleppler
- Carol Avery - Mother
- Fayelyn Bilodeau - Daughter
- Chris L. McKenna - Derek
- Monica Young - Cheryl
- Ayo Sorrells - Mike
- John-Michael Carlton - Josh
- Rosie O'Donnell - Jeanine
- Jennifer Taylor - Alissa
- Dan Aho - Roger
- Diane Delano - Leslie
- Mary-Pat Green - Susie
- Christopher Goodman - Waiter
- Sara Rue - Candace
- Joey Rich - Customer
- Kevin Daniels - Officer Bill
- Jason Olive - Paul
- Andrew James Allen - Jackson
- Andrew Ortega - Jimmy
- Tim Bagley - Dr. LaSalle
- Jack McGee - Frank
- Louise Claps - Linda
- J.J. Boone - Charlotte
- Jennifer Chang - Nurse
- Christina Moore - Camille
- Chris Pratt - Nick
- John O'Brien - Waiter
- Amy Farrington - June
- David James Elliott - Joe
- Claudia Choi - Woman
- Marcus Toji - Walter
- Carrie Armstrong - Carla
- Doc Farrow - Sam
- Chip Chinery - Dave
- Wendie Malick - Danielle
- Carlease Burke - Nurse Patricia
- Dana L. Wilson - Barbara
- Rachel Winfree - Judith
- Neil Ross - Announcer (voice)
- Bret Harrison - Brad
- Jonny Coyne - Victor Perugian
- Nathan Anderson - Guy
- John Benjamin Hickey - Dr. Sellers
- Yeardley Smith - Enid
- Don McManus - Steve
- David Anthony Higgins - George
- Christine Horn - Officer Carter
- Beth Littleford - Lorraine
- Julia Lester - Emily
- Josh Banday - Boone
- Briana Cuoco - Tabitha
- Danielle Bisutti - Dana
- Amy Hill - Beverly
- Butch Klein - Maitre D'
- Patricia Belcher - Gloria
- Michael Dempsey - Officer Miliner
- Rolando Boyce - Officer Hayes
- Leonard Roberts - Ray
- Amir M. Korangy - Leo
- Brett Wagner - Frankie
- Nicola Lambo - Customer
- Michael Angarano - Cooper
- Steven Banks - Randy
- Steven Banks - Steven
- Steven Banks - Doug
- Lex Lang - Man (voice)
- Karen James - Passenger #1
- E.J. Callahan - Maintenance Man
- Timothy E. Goodwin - Passenger #2
- Ryan Malgarini - Brendan
- Tory N. Thompson - Barry
- Kristin Chenoweth - Miranda
- Lela Lee - Alice
- Karly Rothenberg - Ms. Harrington (voice)
- Steven Weber - Patrick
- Terri Hoyos - Soledad
- Hamilton Mitchell - Jerome
- Michael DiMente - Bruce
- Jazmyn Simon - Vanessa
- Larry Cedar - Male Voiceover (voice)
- Carla Tassara - Announcer (voice)
- Deidrie Henry - Andrea
- Mila Brener - Young Bonnie
- Bob Minor - Officer Roberts
- Travis Guba - Willie
- Jaime Barcelon - Jim
- Patti LuPone - Rita
- Mary Faber - Marla
- Jared Gertner - Peter
- Bill Fagerbakke - Sergeant Gene Reubenzer
- Max Adler - Officer Blankenship
- Jose Moreno Brooks - Alfonso
- Josh Latzer - Tony
- Marcus T. Thomas - Cater Waiter
- Matt Oberg - Geoffrey
- John Rubinstein - Professor Addison
- Maya Lynne Robinson - Amanda
- Stephanie Erb - Louise
- Jayme Andrews - Max
- Lyn Alicia Henderson - Susan
- Constance Zimmer - Professor Stevens
- Miller Tai - Matt
- Pat McNeely - Patty
- Dan Martin - Juan
- Krishna Smitha - Barb
- Eric Allan Kramer - Earl
- Joey Gaytan - Randy
- Susan James Berger - Betty
- Anthony Ma - Ben
- Cleo King - Sandy
- Michelle Ortiz - Stacy
- Maurice G. Smith - Jordan
- Alimi Ballard - Professor Gannon
- Amanda Perez - Lisa
- Liza Fernandez - Miriam
- K.T. Thangavelu - Barbara
- Shea Buckner - Daniel
- Shea Buckner - Daniel (uncredited)
- Iris Braydon - Sharon
- Mike Lane - Mason
- Bianca Lopez - Alice
- Tarina Pouncy - Silvia
- Deepti Gupta - Dhara (voice)
- Nicole Sullivan - Leanne
- Jerry O'Donnell - Howard
- Andrew Pifko - Man (voice)
- Hermie Castillo - Josh
- Hermie Castillo - Kenny
- Niccole Thurman - Stage Manager
- David Cooley - Rob (voice)
- Julie Claire - Vivian
- Jason Boegh - Waiter
- Stephanie McVay - Chelsea
- Sam McMurray - Ned
- Susan Ruttan - Lucy
- Gary Anthony Williams - Warren
- Ellie Reed - Mackenzie
- Konstantin Lavysh - Sergei
- Arber Mehmeti - Misha
- Yevgeniy Kartashov - Dimitry
- Timothy Davis-Reed - Salesman
- Terryn Westbrook - Saleswoman
- Lois Smith - Claire
- Johnathan McClain - Mark
- Winston Story - Dane
- Andrew Ridings - Russell
- Kale Clauson - Owen
- Yvette Nicole Brown - Nora
- Amanda Carlin - Alice
- Rick Overton - Burt
- Reginald VelJohnson - Jim
- John Ratzenberger - Stan
- Jim Turner - Rick
- Daniel Nguyen - Marcus
- Jeff Holman - Bob
- Renée Percy - Shelby
- Grace Rowe - Joan
- Charles Robinson - Mr. Munson
- Phil Buckman - Marv
- Dawan Owens - Dave
- Bernie Kopell - Ken
- Jayson Blair - DJ
- Helen Siff - Nikki (voice)
- Mary Pat Gleason - Mary
- Andrew Lewis Caldwell - Todd
- Lauren Weedman - Angela
- Jack Guzman - Guard
- Paget Brewster - Veronica
- Mario Cantone - Sean
- Kirstin Eggers - Janice
- Keone Young - George
- Tim Chiou - Kevin
- Karen Huie - Betty
- Emily Kosloski - Sandra (voice)
- Anna Maria Horsford - Ms. Ferguson
- Larry Joe Campbell - Mike
- Eva La Dare - Nurse
- Ervin Ross - Parking Attendant
- Michelle Arthur - Belinda
- Becky O'Donohue - GPS Voice (voice)
- Mason McCulley - Christopher
- Patricia Bethune - Wanda
- Francesco Bauco - Marco
- Michael Collins - Steve
- Peter Onorati - Wayne
- Gillian Vigman - Melanie
- Miriam Flynn - Arlene
- Karen Malina White - Natalie
- Elia Cantu - Hostess
- Cole Gerdes - Owen
- Lisa Mason Lee - Owen's Date (uncredited)
- Jennifer Marsala - Amber
- Carolyn Hennesy - Professor Winslow
- Aaron Krebs - Drunk Customer
- Amy Pietz - Rebecca
- Reggie De Leon - Paul
- Kiff VandenHeuvel - Zeke
- LaNisa Renee Frederick - Wanda
- Kevin Pollak - Alvin Biletnikoff
- Rebecca Metz - Bobbi
- Brianna Reed - Sarah
- Rob Brownstein - Dr. Mekizian
- Asante Jones - Corey
- Melody Butiu - Lorena
- Michael Christian Alexander - Officer Wiggins
- Jim Meskimen - Man (voice)
- Susan Chuang - Luanne
- Tyne Daly - Barbara
- Ace Gibson - Arlo
- Lauri Johnson - Beatrice
- Natasha Hall - Shawn
- Mark Fite - Wendell
- Dale E. Turner - Jerry
- Bob Odenkirk - Hank
- Steve Valentine - Rod
- David Theune - Lou
- Stephen Monroe Taylor - Darryl
- Malcolm Foster Smith - Mookie
- Sonya Leslie - Nancy
- Matt Cedeño - Vincent
- Galen Hooks - Melinda
- Dan Bucatinsky - Arthur
- Sandy Martin - Lillian
- Rainn Wilson - Trevor
- Chiquita Fuller - Taylor
- Lilli Birdsell - Lydia
- Virginia Montero - Marta
- Christopher Corbin - Man #1 (O.S.) (voice)
- Wallace Langham - Jerry
- Marcuis Harris - Clayton
- Rob Nagle - MC
- Melanie Lynskey - Shannon
- Rondi Reed - Jolene
- George Anthony Bell - Justice of the Peace
- Will Sasso - Andy
- James Marshall - Judge
- Samantha Cutaran - Receptionist
- Joe Smith - Newscaster (voice)
- Mark Bloom - Armand
- Eddie Diaz - Officer Wayne
- Christine Alicia Rodriguez - Leslie
- Lea Thompson
- Jon Cryer
- Nick Bakay
- Gary Halvorson
- Anthony Joseph Rich
- Ted Wass
- Michael Shipley
- Sam Miller
- Ilana Wernick
- Chelsea Myers
- Anne Flett-Giordano
- Susan McMartin
Rick Overton interpreta a Burt en la serie.
Missi Pyle interpreta a Natasha en la serie.
Beverly D'Angelo interpreta a Lorraine en la serie.
Kathleen Turner interpreta a Cookie en la serie.
Lois Smith hace el papel de Claire.
Mark Adair-Rios interpreta a Dr. Gonzalez en la serie.
Colin Hanks hace el papel de Andy.
Anna Faris hace el papel de Christy Plunkett.
Allison Janney hace el papel de Bonnie Plunkett.
Jaime Pressly interpreta a Jill Kendall en la serie.
Capítulo disponible en las siguientes plataformas:
