- Jim Belushi - Bartolome T. Baxter III (voice)
- Brad Garrett - Diamond Jim Johnson (voice)
- Doris Roberts - Mrs. Hedwig (voice)
- Henry Gibson - Mr. Numblitz (voice)
- Matthew Lillard - Monsieur Ducat (voice)
- Curtis Armstrong - (voice)
- Phil LaMarr - (voice)
- Lauren Tom - (voice)
- Jeff Bennett - (voice)
- Clyde Kusatsu - (voice)
- Candi Milo - (voice)
- Tara Strong - (voice)
- Kathleen Gati - Miss Thornton (voice)
- Kathleen Gati - Miss Thornton (voice; uncredited)
- Kathleen Gati - (voice)
- Neil Patrick Harris - Philip (voice)
- Neil Patrick Harris - (voice)
- Dionne Quan - (voice)
- Nestor Carbonell - Diego (voice)
- April Winchell - (voice)
- April Winchell - Tutor Candidate #3 (voice)
- April Winchell - Secretary / Betty's Mom / Janet Palmer (voice)
- Lacey Chabert - (voice)
- Alan Cumming - (voice)
- Jason Marsden - (voice)
- Liliana Mumy - (voice)
- Cynthia Nixon - (voice)
- Kevin Michael Richardson - (voice)
- Tony Jay - (voice)
- Kay Thompson
- Morris Berger
- Steve Brown
Brad Garrett interpreta a Diamond Jim Johnson (voice) en la serie.
Clyde Kusatsu interpreta a (voice) en la serie.
Mary Mouser hace el papel de Eloise (voice).
Lynn Redgrave hace el papel de Nanny (voice).
Tim Curry interpreta a Mr. Salamone (voice) en la serie.
Rob Paulsen interpreta a Bill (voice) en la serie.
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