- Nick Cannon - Self - Host
- Nick Cannon - Bulldog
- Jamie Foxx - Self - Guest Panelist
- Jason Biggs - Self - Guest Panelist
- Leah Remini - Self - Guest Panelist
- Gabriel Iglesias - Self - Guest Panelist
- Joel McHale - Self - Guest Panelist
- Will Arnett - Self - Guest Panelist
- Yvette Nicole Brown - Self - Guest Panelist
- Jay Pharoah - Self - Guest Panelist
- Carrot Top - Self - Clue Giver
- J.B. Smoove - Self - Guest Panelist
- Kenan Thompson - Self - Guest Panelist
- Robert Smigel - Guest Panelist (as Triumph the Insult Comic Dog)
- Chrissy Metz - Self - Guest Panelist
- Will.i.am - Self - Guest Panelist
- Leslie Jordan - Self - Guest Panelist
- Jodie Sweetin - Self - Clue Giver
- Andrew Lloyd Webber - Self - Guest Panelist
- Chris Daughtry - Rottweiler
- Sharon Osbourne - Self - Guest Panelist
- Gordon Ramsay - Self - Guest Panelist
- Nick Carter - Crocodile
- Aloe Blacc - Mushroom
- Michael Bolton - Self - Singing Partner
- Michael Bolton - Wolf
- Caitlyn Jenner - Phoenix
- Danny Trejo - Raccoon
- Logan Paul - Grandpa Monster
- Mark McGrath - Orca
- Tyrese Gibson - Robopine
- Toni Braxton - Pufferfish
- Tyga - Dalmatian
- Cheyenne Jackson - Frog Prince
- Hayley Orrantia - Ringmaster
- Teyana Taylor - Firefly
- Jesse McCartney - Turtle
- Jesse McCartney - Turtle (archive footage)
- Jesse McCartney - Self - Singing Partner
- Carnie Wilson - Lamb [Wilson Phillips]
- Wendy Wilson - Lamb [Wilson Phillips]
- Chynna Phillips - Lamb [Wilson Phillips]
- Amber Riley - Harp
- Dick Van Dyke - Gnome
- Kandi Burruss - Night Angel
- Kandi Burruss - Self
- Sara Evans - Mustang
- Bill Engvall - Clue Giver
- Deana Carter - Clue Giver
- Alexis Cabrera - Axolotl
- Jennifer Nettles - Guest Panelist
- Malin Åkerman - Squirrel
- Lele Pons - Jackalope
- Jim Lee - Clue Giver
- Helen Mirren - Clue Giver (video)
- Zachary Levi - Clue Giver (video)
- Todrick Hall - Bull
- Todrick Hall - Self
- Victor Oladipo - Thingamajig
- Victor Oladipo - Thingamajig (archive footage)
- Grandmaster Flash - Polar Bear
- D.J. 'Shangela' Pierce - Clue Giver
- Niecy Nash-Betts - Self - Guest Host
- Niecy Nash-Betts - Self - Guest Panelist
- Nick Viall - Clue Giver
- Howie Mandel - Rock Lobster
- Debbie Gibson - Night Owl
- Jon Lovitz - Clue Giver
- Holly Robinson Peete - Self - Video Message
- Holly Robinson Peete - Fairy
- T-Pain - Self - Guest Panelist
- T-Pain - Monster (archive footage)
- T-Pain - Monster
- Shad Moss - Frog (archive footage)
- Shad Moss - Frog
- Sheila E. - Self - Performer
- Danielle Fishel - Self - Clue Giver
- Cecil Glenn - Self - Performer
- Eric Jacobson - Miss Piggy / Fozzie / Animal (voices)
- Jamie Lee Curtis - Special Message (video)
- Nicole Byer - Guest Panelist
- Gilbert Gottfried - Special Message (video)
- Tommy Chong - Pineapple (archive footage)
- Tommy Chong - Pineapple
- Johnny Weir - Egg
- Johnny Weir - Egg (archive footage)
- Laila Ali - Panda (archive footage)
- Laila Ali - Panda
- Kate Hudson - Special Message (video)
- Busta Rhymes - Dragon
- Busta Rhymes - Dragon (archive footage)
- Eric Stonestreet - Guest Panelist
- Drew Pinsky - Eagle
- Drew Pinsky - Eagle (archive footage)
- Lil Wayne - Robot
- Lil Wayne - Robot (archive footage)
- Drew Carey - Llama
- Drew Carey - Llama (archive footage)
- Terry Bradshaw - Deer (archive footage)
- Terry Bradshaw - Deer
- Sherri Shepherd - Penguin
- Sherri Shepherd - Penguin (archive footage)
- Margaret Cho - Poodle (archive footage)
- Margaret Cho - Poodle
- Michael Sanchez - Baby Alien
- Michael Sanchez - Baby Alien (archive footage)
- Paul Anka - Broccoli
- Paul Anka - Broccoli (archive footage)
- Chaka Khan - Miss Monster
- Chaka Khan - Miss Monster (archive footage)
- Wendy Williams - Lips
- Wendy Williams - Lips (archive footage)
- Raven-Symoné - Black Widow
- Raven-Symoné - Black Widow (archive footage)
- Tony Hawk - Elephant
- Tony Hawk - Elephant (archive footage)
- Dionne Warwick - Mouse
- Dionne Warwick - Mouse (archive footage)
- Ricki Lake - Raven
- Ricki Lake - Raven (archive footage)
- La Toya Jackson - Alien (archive footage)
- La Toya Jackson - Alien
- Tom Bergeron - Taco
- Tom Bergeron - Taco (archive footage)
- Brian Austin Green - Giraffe
- Brian Austin Green - Self
- Brian Austin Green - Giraffe (archive footage)
- Patti LaBelle - Flower (archive footage)
- Patti LaBelle - Flower
- Ninja - Ice Cream
- Ninja - Ice Cream (archive footage)
- Sarah Palin - Bear
- Sarah Palin - Bear (archive footage)
- Rumer Willis - Lion (archive footage)
- Rumer Willis - Lion
- Michelle Williams - Butterfly (archive footage)
- Michelle Williams - Butterfly
- Mickey Rourke - Gremlin (archive footage)
- Mickey Rourke - Gremlin
- Mickey Rourke - Self
- Bella Thorne - Swan
- Bella Thorne - Swan (archive footage)
- JoJo Siwa - T-Rex
- JoJo Siwa - T-Rex (archive footage)
- Wayne Brady - Fox
- Wayne Brady - Fox (archive footage)
- Wayne Brady - Self - Guest Panelist
- Ana Gasteyer - Self
- Ana Gasteyer - Tree
- Ana Gasteyer - Tree (archive footage)
- Jordyn Woods - Kangaroo
- Jordyn Woods - Kangaroo (archive footage)
- Matt Vogel - Kermit the Frog (voice)
- Matt Vogel - Snail (as Kermit the Frog)
- Gladys Knight - Self - Video Message
- Gladys Knight - Queen Bee (archive footage)
- Gladys Knight - Bee
- Tori Spelling - Unicorn (archive footage)
- Tori Spelling - Self - Clue Giver
- Seal - Leopard
- Seal - Leopard (archive footage)
- LeAnn Rimes - Self - Guest Panelist
- LeAnn Rimes - Sun
- LeAnn Rimes - Sun (archive footage)
- Donny Osmond - Self - Guest Panelist
- Donny Osmond - Peacock
- Donny Osmond - Peacock (archive footage)
- Faith Evans - Self
- Faith Evans - Skunk
- Katharine McPhee - Self
- Katharine McPhee - Banana Split - Ice Cream
- Bobby Berk - Caterpillar
- Bobby Berk - Self
- David Foster - Self
- David Foster - Banana Split - Banana
- Vivica A. Fox - Self
- Vivica A. Fox - Mother Nature
- Anthony Anderson - Self - Guest Panelist
- Anthony Anderson - Rubber Ducky
- Dwight Howard - Self
- Dwight Howard - Octopus
- Phil McGraw - Special Message (via video)
- Willie Robertson - Mallard
- Willie Robertson - Self
- Hilary Swank - Special Message (via video)
- Larry the Cable Guy - Self
- Larry the Cable Guy - Baby
- Judge Greg Mathis - Self - Special Message (via video)
- Ruth Pointer - Self
- Ruth Pointer - Cupcake
- John Lydon - Self
- John Lydon - Jester
- Cheryl Hines - Self - Guest Panelist
- Emily Hampshire - Special Message (via video)
- Rob Schneider - Hamster
- Rob Schneider - Self
- June Shannon - Beach Ball
- June Shannon - Self
- Paul Shaffer - Skeleton (archive footage)
- Paul Shaffer - Self - Video Message
- Paul Shaffer - Skeleton
- Chris Pratt - Self - Video Message
- Jerry Rice - Special Message (via video)
- Joey Fatone - Self - Video Message
- Joey Fatone - Rabbit (archive footage)
- Joey Fatone - Rabbit
- William Shatner - Knight
- William Shatner - Knight (archive footage)
- Eric Idle - Hedgehog
- Eric Idle - Hedgehog (archive footage)
- Michael Strahan - Special Message (via video)
- Chris Kirkpatrick - Hummingbird (archive footage)
- Chris Kirkpatrick - Hummingbird
- Jeff Dunham - Pi-Rat
- Jeff Dunham - Pi-Rat (archive footage)
- Jane Fonda - Special Message (via video)
- Montell Jordan - Panther
- Montell Jordan - Panther (archive footage)
- Barry Williams - Mummy (archive footage)
- Barry Williams - Mummy
- Courteney Cox - Special Message (via video)
- Christopher Knight - Mummy
- Christopher Knight - Mummy (archive footage)
- Duff Goldman - McTerrier
- Duff Goldman - McTerrier (archive footage)
- Lily Pearl Black - Self
- Lily Pearl Black - Self - Video Message
- Mike Lookinland - Mummy
- Mike Lookinland - Mummy (archive footage)
- Jewel - Queen of Hearts
- Jewel - Self - Performer
- Jewel - Self
- Jorge Garcia - Cyclops (archive footage)
- Jorge Garcia - Cyclops
- Daymond John - Fortune Teller
- Daymond John - Fortune Teller (archive footage)
- Mario Cantone - Maize
- Mario Cantone - Maize (archive footage)
- Gloria Gaynor - Mermaid
- Gloria Gaynor - Mermaid (archive footage)
- Adrienne Bailon-Houghton - Flamingo
- Adrienne Bailon-Houghton - Self - Performer
- Natasha Bedingfield - Pepper
- Jerry Springer - Beetle
- Jerry Springer - Beetle (archive footage)
- Kat Graham - Robo-Girl (archive footage)
- Kat Graham - Robo-Girl
- Duane 'Dog' Chapman - Armadillo (archive footage)
- Duane 'Dog' Chapman - Armadillo
- Jennifer Holliday - Miss Teddy (archive footage)
- Jennifer Holliday - Miss Teddy
- Shaggy - Space Bunny (archive footage)
- Shaggy - Space Bunny
- Linda Blair - Scarecrow
- Linda Blair - Scarecrow (archive footage)
- Ray Parker, Jr. - Sir Bug-a-Boo
- Ray Parker, Jr. - Sir Bug-a-Boo (archive footage)
- Clint Black - Sir Snow Owl
- Clint Black - Self - Video Message
- Clint Black - Self
- Lisa Hartman - Self
- Lisa Hartman - Self - Video Message
- Lisa Hartman - Lady Snow Owl
- Nikki Glaser - Snowstorm
- Nikki Glaser - Snowstorm (archive footage)
- Omarion - Yeti (archive footage)
- Omarion - Yeti
- Rita Wilson - Guest Panelist
- Bret Michaels - Self
- Bret Michaels - Self - Performer
- Bret Michaels - Banana
- Bret Michaels - Self - Video Message / Banana (archive footage)
- Bobby Brown - Crab
- Tamera Mowry-Housley - Seashell
- Tori Kelly - Seahorse
- Tori Kelly - Self
- Tori Kelly - Seahorse (archive footage)
- Tori Kelly - Seahorse (archive footage)
- Rob Riggle - Guest Panelist
- Taylor Hanson - Russian Doll
- Isaac Hanson - Russian Doll
- Chloe Kim - Jellyfish
- Chloe Kim - Self
- Chloe Kim - Jellyfish (archive footage)
- Zac Hanson - Russian Doll
- Chris Irvine - T-Rex Bride
- Chris Irvine - Bride (archive footage)
- Darius Rucker - Guest Panelist
- Adam Carolla - Avocado
- Adam Carolla - Avocado (archive footage)
- George Foreman - Venus Fly Trap
- George Foreman - Venus Fly Trap (archive footage)
- George Clinton - Gopher
- George Clinton - Gopher (archive footage)
- Joey Lawrence - Walrus (archive footage)
- Joey Lawrence - Walrus
- Bob Saget - Self - Video Message
- Bob Saget - Self
- Bob Saget - Squiggly Monster (archive footage)
- Bob Saget - Squiggly Monster
- Wiz Khalifa - Chameleon
- JoJo - Black Swan
- Nick Lachey - Piglet
- Kelly Osbourne - Ladybug (archive footage)
- Kelly Osbourne - Self - Clue Giver
- Kelly Osbourne - Ladybug
- Craig Robinson - Guest Panelist
- Rhona Bennett - Queen Cobra [En Vogue]
- Rhona Bennett - Queen Cobra (archive footage)
- Penn Jillette - Hydra (archive footage)
- Penn Jillette - Hydra
- Terry Ellis - Queen Cobra [En Vogue]
- Terry Ellis - Queen Cobra (archive footage)
- Christie Brinkley - Lemur
- Christie Brinkley - Lemur (archive footage)
- Teller - Hydra
- Teller - Hydra (archive footage)
- Joe Buck - Ram
- Joe Buck - Ram (archive footage)
- Cindy Herron - Queen Cobra [En Vogue]
- Cindy Herron - Queen Cobra (archive footage)
- Rudolph Giuliani - Jack-in-the-Box (archive footage)
- Rudolph Giuliani - Jack-in-the-Box
- Kirstie Alley - Baby Mammoth (archive footage)
- Kirstie Alley - Baby Mammoth
- Luann de Lesseps - Clue Giver
- Luann de Lesseps - Hibiscus
- Eric Finch - Snoop Dogg Look-a-Like - Guest Panelist
- Jeff Dye - Guest Panelist
- John Oates - Special Message (video)
- John Oates - Anteater
- Rob Gronkowski - White Tiger
- Rob Gronkowski - White Tiger (archive footage)
- Jackie Evancho - Kitty (archive footage)
- Jackie Evancho - Kitty
- Le'Veon Bell - Milkshake
- Le'Veon Bell - Milkshake (archive footage)
- Le'Veon Bell - Self - Performer / Clue Giver
- Donnie Wahlberg - Self
- Donnie Wahlberg - Cluedle-Doo
- Taylor Dayne - Popcorn
- Taylor Dayne - Popcorn (archive footage)
- Taylor Dayne - Self - Performer
- Hunter Hayes - Astronaut
- Hunter Hayes - Astronaut (archive footage)
- Hunter Hayes - Self - Performer
- Erik Estrada - Clue Giver
- Charlene Tilton - Clue Giver
- George Wendt - Moose
- Christine Bently - Scorpio
- Daphne Zuniga - Clue Giver
- Dee Snider - Doll
- Alicia Witt - Dandelion
- Melissa Joan Hart - Lamp
- Lou Diamond Phillips - Mantis
- Keenan Allen - Gargoyle
- Olivia Culpo - UFO
- Scott Hoying - [Pentatonix] California Roll
- Mitch Grassi - [Pentatonix] California Roll
- Kirstin Maldonado - [Pentatonix] California Roll
- Kevin Olusola - [Pentatonix] California Roll
- Matthew Sallee - [Pentatonix] California Roll
- David Archuleta - Macaw
- Demi Lovato - Anonymouse
- Lance Bass - Self - Clue Giver
- Kate Flannery - Self - Clue Giver
- Antonio Gates - Self - Clue Giver
- DeSean Jackson - Self - Clue Giver
- Tom Sandoval - Diver
- Michael Rapaport - Pickle
- Billie Jean King - Royal Hen
- Tyler Posey - Hawk
- Metta Sandiford-Artest - Cuddle Monster
- Ashley Parker Angel - S'more
- Ginuwine - Husky
- Sebastian Bach - Tiki
- Keyshia Cole - Candelabra
- Macy Gray - Sea Queen
- Janel Parrish - Gazelle
- John Schneider - Donut
- Marvin Young - Performer / Clue Giver
- Alex Rudzinski
- Hayley Broderick
- Tiana Gandelman
- Chloe Storey
- Jessica Taylor
- Emily Smith
- Ethan Ellenberger
- Ralik Rachman
- Elizabeth Part
- Nick Campagna
- Meryl Ginsberg
- Miguel Gandelman
Kirstie Alley interpreta a Baby Mammoth (archive footage) en la serie.
Alicia Witt hace el papel de Dandelion.
Michael Rapaport interpreta a Pickle en la serie.
Donnie Wahlberg interpreta a Self en la serie.
Jamie Foxx hace el papel de Self - Guest Panelist.
Hilary Swank interpreta a Special Message (via video) en la serie.
Nick Cannon interpreta a Self - Host en la serie.
William Shatner interpreta a Knight (archive footage) en la serie.
Emily Hampshire hace el papel de Special Message (via video).
Vivica A. Fox interpreta a Mother Nature en la serie.
Capítulo disponible en las siguientes plataformas:
