- Michael Brown - Winston Moreland
- Roger Guenveur Smith - Booker T. Washington
- Cornelius Smith, Jr. - W.E.B. DuBois
- Rothaford Gray - Reverend Smith
- Karen Glave - Peggie Prosser
- Tymika Tafari - Woman #1
- Gina James - Woman #2
- Joel Rinzler - White Man #1
- Edwige Jean-Pierre - Washerwoman
- Robert Ifedi - Davis
- Mouna Traoré - Esther
- Janelle Heron - Sales Agent #1
- Allison Wilson-Forbes - Elvira
- Joanne Reece - Gertrude
- Osias Reid - Newsboy
- Shawn Cotterell - Choir Singer
- Chris Tarpos - Townsman (uncredited)
- Bill Bellamy - Sweetness
- Kimberly Huie - Margaret Washington
- Sydney Morton - Dora Larrie
- Gairey Richardson - Lawyer
- Zahra Bentham - Nettie Ransom
- Mark Taylor - Emmett Jay Scott
- Jeremiah Sparks - Band Leader
- Mark Sparks - Landowner
- Shakura S'Aida - Claire Thomas
- Colin Edwards - Reporter
- Jason Burke - Farmer #1
- Okiki Kendall - Cake Walk Dancer (uncredited)
- Destiny Rettinger - Female Tap Dancer (uncredited)
- Remi Adéyinka - Birdie
- Vanessa Mitchell - Mildred
- Rashaana Cumberbatch - Ruby
- Joanne Jansen - Walker Girl
- Derick Agyemang - Chester
- Olivia Croft - Josephine Moreland
- Lili Francks - Clarissa
- Carson Durven - Peter
- Chris Robinson - Porter
- Douglas E. Hughes - Sullivan
- Brianna Goldie - Walker Girl #2
- Kiki Hammill - Fairy Mae
- Keeya King - Peaches
- Frank Moore - John D. Rockefeller
- Desmond Campbell - Owen
- Jael Obasi - Little Sarah
- Samantha Kaine - Sales Agent #1
- Novie Edwards - Sales Agent #2
- Stuart Hughes - Percy Saunders
- Glen Michael Grant - Doctor Ward
- Nneka Elliott - Sales Agent #3
- Nayo - Sales Agent #4
- Blessing Adedijo - Sales Agent #5
- Patrice Henry - Sales Agent #6
- Hillary Daley - Whitman Sister #1
- Andrew Perun - White Attacker #3
- Suzanne Coy - 1930's Employee
- Claudia Hamilton - 1970's Employee
- Dorrett White - Washerwoman (uncredited)
- A'Lelia Bundles
- Tyger Williams
- Janine Sherman Barrois
- DeMane Davis
- Luis Patiño
- Octavia Spencer
- LeBron James
- Lena Cordina
- Abe Rounds
- Larry Goldings
Octavia Spencer interpreta a Madam C. J. Walker en la serie.
Tiffany Haddish hace el papel de Lelia.
Carmen Ejogo interpreta a Addie en la serie.
Garrett Morris hace el papel de Cleophus Walker.
Kevin Carroll interpreta a Ransom en la serie.
J. Alphonse Nicholson hace el papel de John Robinson.
Blair Underwood interpreta a Charles James Walker en la serie.
Capítulo disponible en las siguientes plataformas:
