- Jon Hamm - Tony Stark / Iron Man (voice)
- Nathan Fillion - Simon Williams / Wonder Man (voice)
- Whoopi Goldberg - Marian Pouncy / Poundcakes (voice)
- Chris Parnell - Alvin Healy / Tenpin (voice)
- Eddie Pepitone - Bruno Horgan / Melter (voice)
- John DiMaggio - A.I.M. agent (voice)
- John DiMaggio - Rodney (voice)
- Meredith Salenger - Whitney Frost / Madame Masque / Club Supervisor (voice)
- Meredith Salenger - Brandi (voice)
- Brian Posehn - General Dagger (voice)
- Lennon Parham - Doris / Mrs. Horgan (voice)
- Alan Tudyk - Arcade (voice)
- Kevin Michael Richardson - David Cannon / Whirlwind (voice)
- Dustin Ybarra - Antonio Rodriguez / Armadillo (voice)
- Jack Kirby
- Stan Lee
- Whitney Loveall
- Paula Haifley
- Joe Quesada
- Matthew Senreich
- Itai Grunfeld
- Seth Green
- Daniel Rojas
Whoopi Goldberg hace el papel de Marian Pouncy / Poundcakes (voice).
Patton Oswalt interpreta a George Tarleton / M.O.D.O.K. (voice) en la serie.
Melissa Fumero interpreta a Melissa Tarleton (voice) en la serie.
Aimee Garcia hace el papel de Jodie Ramirez-Tarleton (voice).
Ben Schwartz interpreta a Louis 'Lou' Tarleton (voice) en la serie.
Wendi McLendon-Covey interpreta a Monica Rappaccini / Scientist Supreme (voice) en la serie.
Beck Bennett interpreta a Austin Van Der Sleet (voice) en la serie.
Jon Daly interpreta a Super-Adaptoid (voice) en la serie.
Sam Richardson hace el papel de Gary Garoldson (voice).
Capítulo disponible en las siguientes plataformas:
