- Rupert Penry-Jones - Samuel Blake
- Sagar Radia - PC Tariq
- Emily Taaffe - Mel
- Josh Taylor - Kevin Jones
- Charles Babalola - Ade Okeyale
- Bradley John - Frankie
- Jonathan Aris - Ralph Dickenson
- Ffion Jolly - Melanie Spencer
- Matthew McNulty - Rob Spencer
- Brett Allen - Sean Blake
- Conleth Hill - Reverend Huxley
- Leilah de Meza - Daisy Clayton
- Sam Benjamin - Mark Travis
- Craig Vye - Donato
- Jon Tarcy - Anton
- Sendhil Ramamurthy - Nikhail Julian
- Joe Sims - Thomas Rice
- Jonathan Kerrigan - Jonny
- Sally Plumb - Beverley Donoghue
- Arthur Lee - Rui Hirota
- Jeff Alexander - David Thomas
- Richard Cunningham - Casino Manager
- Adam Sopp - Croupier 1
- Ross Green - Croupier 2
- Tom Reed - Ajit Malhotra
- Harvey Virdi - Shefali Malhotra
- Martin Pemberton - Mugger
- Ryan Gage - Davey Wells
- Leo Hatton - Mary Wells
- Rebecca Grant - Lakshi Perera
- Tamla Kari - Rachel Spikes
- Stan Lee - Himself
- Charlene McKenna - Clare Cartmell
- Glenn Speers - Buster Wiley
- Jessica Boyde - Julie Tracey
- Stefan Boehm - Dr Jones
- Rhys Yates - Jake
- Yoon C. Joyce - Bo Jing
- Gia Labarbera - Police Woman (uncredited)
- Adam Treasure - Soco
- Andrew Moore - Gambling Addict
- Sarah Turner - Kayleigh Fenchurch
- Patrick James Stephens
- Corinne Bailey Rae
- Ben Bartlett
- Nick Green
Steven Mackintosh interpreta a DSI Winter en la serie.
James Nesbitt hace el papel de Harry Clayton.
Sienna Guillory interpreta a Eve en la serie.
Amara Karan interpreta a Suri Chohan en la serie.
Darren Boyd interpreta a DI Orwell en la serie.
Rupert Penry-Jones hace el papel de Samuel Blake.
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