- Paul Stolarsky - Hammer
- Allen Williams - Adam Wilson
- Allen Williams - Assistant Foreign Editor
- Reni Santoni - Jim Keenan
- Mike Henry - Frank
- Barbara Tarbuck - Mother
- Linda Carlson - Carol
- Christopher Cazenove - Peter Witter
- Pat Morita - Ike Tatsumi
- Carmen Argenziano - Arnold Zinner
- Michael Constantine - Sidney Kovac
- Pat Corley - Organizer
- Brian Dennehy - Wilson
- Joe Mantell - Simmons
- Michael Alldredge - Sgt. Roche
- Cliff Potts - Ted McCovey
- Phillip Pine - Lindsay
- Jeff Corey - Larry Hill
- Peggy McCay - Marian Hume
- Tom Atkins - Dr Sorensen
- Tom Atkins - Jim Bronsky
- Tom Atkins - Frank Dunning
- Barney Phillips - Dr. Dick Barnes
- Sheila Larken - Rosalie Wilson
- Jonathan B. Woodward - Eric Kuzik (as Jonathan Woodward)
- Michael Morgan - Tom
- Bobby Rolofson - 5th Grader (as Robert Rolofson)
- David Armstrong - Protestor (uncredited)
- Charles Bracy - Leon
- Rebecca Balding - Carla Mardigian
- Stanley Kamel - Marty Niles
- Nicholas Colasanto - Patsy Reese
- Shannon Eubanks - Secretary
- Kene Holliday - J.D.
- J. Jay Saunders - Neil Turner
- Robert Davi - Hector
- Bartlett Robinson - Jacob Bauman
- Art LaFleur - Ben
- George Wyner - Jeff Benedict
- Mariclare Costello - Louise Larsen
- Keene Curtis - Coach Diehl
- Keene Curtis - Doctor at hospital
- Sharon Spelman - Jeanette Pepper
- Michael Leon - Jimmy Lee Grey
- Harold Gould - Dr. George Duncan
- Arthur Tovey - Dr. Van Dragen (uncredited)
- Gary Pagett - Trib Lawyer
- Gary Pagett - Financial Editor
- Gary Pagett - Assistant National Editor
- Robert Rothwell - Policeman (uncredited)
- Robert Rothwell - Poster
- William Schallert - Larry Hill
- Julia Duffy - Charlene
- Macon McCalman - Dolph Masterson
- Macon McCalman - Elliot Kibbee
- Harold J. Stone - Fred Gruber
- Robert Casper - Gary Kellum
- Jean Allison - Mrs. Morrison (uncredited)
- John Considine - David Milburn
- J. Pat O'Malley - Patrick Terhune
- Mark James - Eddie
- Earl Boen - Vice-Cop
- George Murdock - Sgt. Irwin Winowsky
- Bob Harks - Reporter (uncredited)
- Bob Harks - Restaurant Patron (uncredited)
- Ted Gehring - Chief Rankin
- Bill Erwin - Old Man
- Gordon Jump - National Editor
- Peter Brocco - Mr. Sturner
- Joseph Mascolo - McIntyre
- Dorothy Dells - Nurse #2
- Allyn Ann McLerie - Betty Newman
- Marshall Thompson - Paul Newman
- Buck Kartalian - Leon Hartounian
- Magda Harout - Lavenia Hartounian
- Charles Hallahan - Chet Wilke
- Charles Hallahan - Chuck
- Jean Howell - Nancy Downey
- Meshach Taylor - Marcus Prescott
- Meshach Taylor - Kinsasha
- Michael Fairman - Dr. Thomas Chamberlain
- Charles Cyphers - Jerry Baldwin
- Fran Bennett - Sarah
- Fran Bennett - Chaney
- David Ackroyd - Mike Kessler
- Arthur Taxier - Dale Tollifer
- Norman Burton - Franklin Nash
- Alan Haufrect - Chope
- Alan Haufrect - National Editor
- Stanley Grover - DTW Official
- Kenneth Tigar - Eugene Smithfield
- Kenneth Tigar - Defense Attorney Patterson
- Michael Jeter - Max Galt
- Ned Romero - Howard Sweetwater
- Paul Bryar - Parkins
- Richard Jaeckel - Dan Staley
- Peter Marshall - Art McQueen
- Geoffrey Lewis - Sheriff
- Read Morgan - Field Costello
- Read Morgan - Deputy Rutledge
- Read Morgan - Deputy
- Read Morgan - Lieutenant
- John Blyth Barrymore - Harold
- John Blyth Barrymore - Marc Pauley
- Jordan Rhodes - Schultz
- Michele Gallery
- Leon Tokatyan
- Steve Kline
- Leonora Thuna
- Johnny Dawkins
- Michael Vittes
- Gene Reynolds
- James L. Brooks
- Gary David Goldberg
- Seth Freeman
- Roger Young
- Allan Burns
- Patrick Williams
Robert Davi interpreta a Hector en la serie.
Ed Asner hace el papel de Lou Grant.
Robert Walden interpreta a Joe Rossi en la serie.
Linda Kelsey hace el papel de Billie Newman.
Mason Adams interpreta a Charlie Hume en la serie.
Jack Bannon hace el papel de Art Donovan.
Daryl Anderson hace el papel de Dennis Price.
Nancy Marchand interpreta a Margaret Pynchon en la serie.
Allen Williams interpreta a Adam Wilson en la serie.
Paul Stolarsky hace el papel de Hammer.
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