- Jing Lusi - Kiera
- Marilyn Uribe - Woman 1
- Kale Culley - Young Alex Myers
- Miguel Anthony - Security Guard
- Issy Stewart - Tatiana
- Shannon Dang - Mia Zhang
- Scarlet Dergal - The Receptionist
- Aaron Eckhart - Greg
- Marthe Keller - Anushka
- Louise Bourgoin - Sophie
- Inès Melab - Hajar
- Darina Al Joundi - Raha Azim
- Mouss Zouheyri - Mohammed Azim
- Mounir Amamra - Amir Azim
- Franc Bruneau - JP
- Vernon Dobtcheff - M. Audran
- Évelyne Dandry - Mme. Audran
- Xavier Thiam - Dr. Shrom
- Salomé Diénis Meulien - Sonya
- Laurent Bateau - Denis
- Alexandra Cismondi - Lydia
- Grégoire Baujat - Paul
- Guslagie Malanda - Clotilde
- Gauthier Battoue - EMT
- Victoire Gonin-Labat - Female Shopper
- Tatiana Gontcharova - Lena
- Corey Stoll - Michael Romanoff
- Kerry Bishé - Shelly Romanoff
- Janet Montgomery - Michelle Westbrook
- Noah Wyle - Ivan
- Braeden Lemasters - Andrew
- Larry Bates - Darryl
- Brian Bisson - Scott
- Nora Sheehan - Mona
- Arlene Duncan - Prosecutor Dion
- Anita La Selva - Judge Garcia
- Christina Hendricks - Olivia Rogers
- Jack Huston - Samuel Ryan
- Paul Reiser - Bob Isaacson
- Isabelle Huppert - Jacqueline
- Mike Doyle - Brian Norris
- Mark Valley - Steve Lewis
- Евгения Брик - Katrina
- Morten Suurballe - Max Gruber
- Ivan G'Vera - Lazlo Barta
- Cornelia Ivancan - Gillian
- Jaschka Lämmert - Liesel
- Amanda Peet - Olivia Wells
- Jon Tenney - Eric Ford
- Mary Kay Place - Marilyn Hopkins
- Michael O'Neill - Ron Hopkins
- John Slattery - Daniel Reese
- Diane Lane - Katherine Ford
- Anni Krueger - Young Julia
- John Way - Young Eric
- Sasha Diamond - Young Lisa
- Andrew Rannells - David Patton
- Cara Buono - Debbie Newman
- Nicole Ari Parker - Cheryl Gowans
- Ron Livingston - Alex Myers
- Thaddeaus Ek - Benji Myers
- Joshua Carlon - Henry Myers
- JJ Feild - Jack
- JJ Feild - Jack Edgar
- Uriah Shelton - Julian Myers
- Alexandra Barreto - Detective Gutierrez
- Jennifer Parsons - Mrs. Swanson
- Radha Mitchell - Victoria Hayward
- Juan Pablo Castaneda - Abel
- Griffin Dunne - Frank Shefflied
- Paul Luke Bonenfant - Nick Hayward
- David Sutcliffe - Philip Hayward
- Roberto Medina - Dr. Eduardo Siquieros
- María Evoli - Lourdes Gonzalez
- Kathryn Hahn - Anka
- Jay R. Ferguson - Joe Garner
- Annet Mahendru - Elena Evanovich
- Stephanie McVay - Barb Callahan
- Marina Weis - Mrs. Fedunov
- Anastasija Marčenkaitė - Vera
- Zofia Wichłacz - Nadya
- Ieva Andrejevaitė - Young Woman at Airport
- Hugh Skinner - Simon Burrows
- Hera Hilmar - Ondine
- Ben Miles - George Burrows
- Adele Anderson - Candace
- Oliver Zetterström - Young Simon
- Deirdre Mullins - Natalie Burrows
- Rebecca Root - Dana
- Jane Perry - Belinda
- Christopher Goh - Christopher Ming
- Andrew Buckley - Doctor
- Josh Madryga - Kurt Davis
- Shannon Wilcox - Natalie
- James Naughton - Dmitri
- Laura Gardner - Dr. Crawford
- Neville Edwards - Mr. Clarence
- Mark Caven - Dr. Bennett
- Edoardo Beghi - Andreas
- Patrick Creery - Emcee
- Blair Williams - Grand Duke
- Rod Campbell - Nicholas
- Elva Mai Hoover - June
- Mary Long - Olga
- Timm Zemanek - Albert
- Kyle Pacek - Rasputin
- David Kerr - Ship Bartender
- Shaun Clarke - Champagne Soldier
- Stewart Downs - Nicholas
- Raeanna Guitard - Czarina
- Korina Rothery - Royal Daughter
- Raven Cinello - Officer Torrance
- Earl McLean Jr. - Jury Clerk
- Iva Babić - Gretchen
- Goran Navojec - Karl
- Thomas Nash - Hans
- Markus Gertken - Maître D'
- Františka Brzobohatá - Olga
- Markéta Gajdošová - Anastasia
- Marie Page - Little Girl
- Ambre Anderson - Mother
- Bryan Fitzgerald - Young Man
- Chelsea Taylor - Laughing Girl
- Carina Battrick - Little Ella
- Prianga Pieris - Cabbie
- Janne Mortil - Gloria
- David Ferry - Gary Beethoven
- Heather Dicke - Monica
- Dwight Ireland - Doctor 1
- Joseph DeVito - Subway Pervert
- Craig Brown - Doctor 2
- Rob Evors - George Myers
- Maggie Gwin - Sarah Myers
- Henry Kaufman - Tommy
- Zemyhe Curtis - Larry
- Paxton Booth - Young Henry
- Gregory E Freeman - Aaron
- Paige Searcy - Chloe
- Sandra Quiróz - Nurse Ortega
- Paul Gregory - Rupert Stanley
- Maggie Benedict - Personal Nurse
- Sergio Rogalto - Concierge
- Núria Blanco - Woman 2
- Sandra Debelak - Woman 4
- Estephania Barba - Woman 5
- Regina Spektor - Special Vocal Performance
- Oleg Nasobin - Orphanage Security Guard
- Olga Louzgina - Russian Judge
- Radu Bânzaru - Money Exchange Man
- Gabriel Răuță - Store Security Guard
- Kathy Ciric
- Maria Jacquemetton
- Semi Chellas
- Blake McCormick
- Nathaniel Smith
- Carrie Audino
Paul Reiser interpreta a Bob Isaacson en la serie.
Griffin Dunne interpreta a Frank Shefflied en la serie.
Vernon Dobtcheff interpreta a M. Audran en la serie.
Amanda Peet interpreta a Olivia Wells en la serie.
Jon Tenney hace el papel de Eric Ford.
Jing Lusi hace el papel de Kiera.
Marilyn Uribe interpreta a Woman 1 en la serie.
Kale Culley interpreta a Young Alex Myers en la serie.
Miguel Anthony interpreta a Security Guard en la serie.
Issy Stewart hace el papel de Tatiana.
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