- Candace Cameron Bure - Jenny Foster
- Brian Peck - Pizza Man
- Matthew Perry - Sandy
- Biff McGuire - Simmons
- Ami Dolenz - Linda
- Cathy Podewell - Lydia Shayne
- Deborah Harmon - Elizabeth Lubbock
- Julie McCullough - Julie Costello
- Carmen Filpi - Fred
- Stuart Nisbet - George Washington
- K.C. Martel - Eddie
- Hilary Swank - Sasha Serotsky
- Jenny Lewis - Judy Jones
- Tricia Leigh Fisher - C.J. Powell
- Dick Van Patten - Nick Simpson
- Jane Kean - Kathleen
- Derek McGrath - Encyclopedia Salesman
- Brian Robbins - Mitch
- Earl Boen - Dr. Marlen
- Dana Plato - Lisa
- Keith Coogan - Scottie
- James T. Callahan - Uncle Bob
- Philip Sterling - Dr. Miller
- Summer Phoenix - Jody
- Jo De Winter - Mrs. Salinger
- Timothy Gibbs - Jerry Delish
- Kimberley Kates - Sheena 'Woo Woo' Berkowitz
- Franklyn Seales - Dr. Jerry Marquez
- Kelly Hu - Melia
- Heidi Zeigler - Sherry
- Jane Powell - Irma Seaver Overmier
- Beth Toussaint - Morgan Chase
- Kevin Brophy - Ray
- Judie Aronson - Cindy
- Carol Ann Susi - Norma
- Christian Hoff - Student #1
- Khrystyne Haje - Teenage Chrissy Seaver
- Michael Gregory - Cop
- Raymond Singer - Rick
- Jonna Lee - Becky
- Danny Nucci - Scooter Krassner
- Hallie Todd - The Kid
- Rachel Jacobs - Shelley
- Jill Whitlow - Kim
- James Sloyan - Max Drummond
- Kristy Swanson - Rhonda
- Douglas Seale - Jimmy
- Andrea Barber - Rhonda Green
- Tuc Watkins - Trainer
- Kelly Rowan - Rachel
- Van Epperson - Truman Capote
- Sam Anderson - Principal Willis Dewitt
- Nicholas Pryor - Dr. Frankovich
- Brian Austin Green - Rapper in Fresh Kid's Music Group (uncredited)
- Jay Acovone - Jake
- Forry Smith - Lyle Douglas
- Paul Collins - Jim Kimball
- Ellen Crawford - Dr. Whiteside
- Fred Applegate - Mr. Tedesco
- Stewart Finlay-McLennan - Nigel Dunn
- Shavar Ross - Kenny
- James Lew - Movie Villain #2
- Jeff Lester - Kent
- Ty Miller - Hadley Barnes
- Deborah White - Susan
- Andrew Koenig - Richard 'Boner' Stabone
- Scott Curtis - Rodney
- Scott Curtis - Mark
- Peter Jurasik - Doug Stanton
- Olivia d'Abo - Terry
- Olivia d'Abo - Wendy
- Michael Cudlitz - Chucksteak
- Chelsea Noble - Kate MacDonald
- Gary Grubbs - George Brower
- Dick O'Neill - Chris
- Diane Delano - Sonya Olsen
- Eric Allan Kramer - Tony
- Marianne Muellerleile - Nurse Bauer
- Richard Sanders - Luther
- Richard Sanders - Dr. Rosenfeld
- Larry Poindexter - Andre
- Annette Funicello - Mrs. Hinkley
- Leanna Creel - Schwartz Twin
- Dick Butkus - Robert
- Danny Cooksey - New Ben
- Ralph Manza - Izzy
- Arlene Golonka - Nancy
- Arlene Golonka - Kitty
- Judith Barsi - Little Carol
- Cristine Rose - Roseanne Flagg
- Cristine Rose - Lucy Snyder
- Robert Rockwell - Wally Overmier
- Carlos Lacámara - Crew Member
- Tracy Wells - Marlene
- Gregory Sierra - Dr. Paul Ramirez
- Jerry Vale - Jerry Vale
- Jerry Vale - Self
- Pamela Brull - Thelma
- Jean Kasem - DeDe DeWitt
- Paula Irvine - Lori McNeil
- Hoyt Axton - Claver Jackson
- Kathleen Freeman - Sophie
- Kathleen Freeman - Madge
- Kathleen Freeman - Estelle
- Renée Estevez - Robin
- David Coburn - David
- David Coburn - Doug
- Dawn Wells - Casting Receptionist
- Dawn Wells - Myrtle Deforest
- Kit McDonough - Mrs. Scoffengerio
- Linda Carlson - Margo Drummond
- Kari Lizer - Stewardess
- Jeannine Renshaw - Gretchen
- Michael A. Goorjian - Hank Miller
- Shannon Day - Melanie
- Joely Fisher - Sally Garner
- Susan Griffiths - Marilyn Monroe
- Dan Lauria - Dan
- Dan Lauria - Hockey Coach
- Julie Cobb - Gracie Thornton
- Julie Cobb - Mrs. Dufelder
- Karen Hensel - Dr. Goodner
- Mel Brandt - Accordian Player
- Heather Graham - Cindy
- Kenneth Tigar - Sid Sidlevich
- Peter Hansen - Mr. Littlefield
- Robin Thicke - Boy at Party
- Robin Thicke - Ralph
- Bill Kirchenbauer - Coach Lubbock
- Ahmet Zappa - Louie
- Ahmet Zappa - Barry
- Susan Krebs - Marsha
- Pat Crawford Brown - Kathleen
- Robert Costanzo - Ernie
- Michael Dempsey - Officer
- Anjul Nigam - Raj
- Anjul Nigam - Sub #2
- Timothy Scott - Fool (Larry Leaky)
- Ben Frank - Captain
- William Cort - Mr. Hinkley
- Jennie Garth - Denise
- Abraham Benrubi - Really Big Kid
- Heidi Kozak - Bonnie
- Danielle Harris - Susie Maxwell
- Patrick Cranshaw - Reverend Chuck MacGregor
- Butch Hartman - Robert Jordan
- Matt Shakman - Graham Jr.
- Dennis Haysbert - Police Officer
- Dennis Haysbert - Officer Wright
- Dennis Haysbert - Frank
- Parley Baer - Counterman
- Kim Valentine - Shauna
- Brad Pitt - Jonathan Keith
- Brad Pitt - Jeff
- Jennifer Nash - Margo
- Gordon Jump - Ed Malone
- James Marshall - Kevin Randall
- James Marshall - Stage Manager
- James Marshall - Actor (uncredited)
- Jarrett Lennon - Little Boner
- Al Ruscio - Stranger
- Archie Lang - Minister
- Charlie Spradling - Tawney
- Wendy Cox - Cheryl Murray
- Peggy Doyle - Big Al's Mom
- Jamie Luner - Cindy
- Jamie Luner - Sheena Berkowitz
- Jamie Luner - Kara Daye
- Tina Caspary - Jamie
- Lesley Boone - Girl
- Lesley Boone - Lesley Boone
- Lesley Boone - Lesley
- Matthew Asner - Delivery Man
- Noah Blake - Tony Di Sipio
- Brooke Theiss - Wendy
- Brooke Theiss - Stacy
- Kedric Wolfe - Hymie Lowenstein
- Skip Young - Coffee Shop Regular
- Heather Langenkamp - Amy Boutilier
- Heather Langenkamp - Marie
- Patrika Darbo - Estelle
- Patrika Darbo - Judy Jones
- Patrika Darbo - Luella
- Bill Erwin - Chester / Lester
- Bill Erwin - Bub
- Bill Erwin - Janitor
- Bill Erwin - Edgar
- Bill Erwin - Maurice
- Bill Erwin - Lloyd
- Bill Erwin - Buzz
- Bill Stevenson - Boom Boom
- Darren Powell - Ken Singleton
- Janet Clark - Yvonne
- Gordon Jennison Noice - Older Hood
- Jason Naylor - Freshman #1
- Leon Fan - Freshman #2
- Arnold Margolin
- Neal Marlens
- Steve Marshall
Brad Pitt interpreta a Jonathan Keith en la serie.
Marianne Muellerleile interpreta a Nurse Bauer en la serie.
Dennis Haysbert interpreta a Frank en la serie.
Danny Cooksey interpreta a New Ben en la serie.
Joely Fisher interpreta a Sally Garner en la serie.
Earl Boen interpreta a Dr. Marlen en la serie.
Hilary Swank interpreta a Sasha Serotsky en la serie.
Alan Thicke interpreta a Jason Seaver en la serie.
Joanna Kerns interpreta a Maggie Seaver en la serie.
Kirk Cameron interpreta a Mike Seaver en la serie.
Capítulo disponible en las siguientes plataformas:
