- Josh Groban - Self
- Laurence Fishburne - Self
- Jay Leno - Self
- Lea Thompson - Self
- Reza Aslan - Reza Aslan
- Elizabeth Banks - Self
- Tom Bergeron - Self
- Meagen Fay - Holly
- Jere Burns - Carl
- Riki Lindhome - Becky
- Layla Alizada - Betty
- Liam Hemsworth - Self
- Nick Offerman - Self
- Christina Applegate - Self
- Ed Helms - Self
- Reese Witherspoon - Self
- Kristin Chenoweth - Self
- Stacey Moseley - Cheryl
- Jason Bateman - Self
- Chelsea Handler - Self
- Joseph Gordon-Levitt - Self
- Dave Grohl - Self
- Mindy Kaling - Self
- Utkarsh Ambudkar - Pache
- June Diane Raphael - Lucy Royce
- Keegan-Michael Key - Self
- Jordan Peele - Self
- RuPaul - Self
- Ingrid Michaelson - Self
- Kat Purgal - Gwynne
- Jimm Giannini - Guiseppe
- Joan Jett - Self
- Willie Nelson - Self
- Jack White - Self
- Rosalind Chao - Woman #1
- Dan Reynolds - Self - Imagine Dragons
- Wayne Sermon - Self - Imagine Dragons
- Ben McKee - Self - Imagine Dragons
- Chris Jai Alex - Cop
- Bill Barretta - Pepe the King Prawn / Dr. Teeth / Rowlf (voice)
- Bill Barretta - Pepe the King Prawn / Dr. Teeth / Rowlf / Bobo the Bear (voice)
- Keylor Leigh - Nurse
- David Rudman - Janice / Scooter (voice)
- David Rudman - Janice / Scooter / Satay (voice)
- David Rudman - Scooter / Janice (voice)
- Jonathan Dixon - Surveyor
- Tim Lagasse - Additional Muppet Performer (voice)
- Matt Vogel - Floyd Pepper / Uncle Deadly (voice)
- Matt Vogel - Floyd Pepper (voice)
- Matt Vogel - Floyd Pepper / Robin (voice)
- Matt Vogel - Floyd Pepper / Uncle Deadly / Sweetums (voice)
- Matt Vogel - Floyd Pepper / Crazy Harry / Sweetums (voice)
- Matt Vogel - Uncle Deadly / Lew Zealand / Crazy Harry / Snowth (voice)
- Bruce Lanoil - Additional Muppet Performer (voice)
- Julianne Buescher - Denise / Yolanda the Rat (voice)
- Julianne Buescher - Yolanda
- Julianne Buescher - Additional Muppet Performer (voice)
- Julianne Buescher - Denise (voice)
- Julianne Buescher - Yolanda the Rat / Debbie (voice)
- Julianne Buescher - Yolanda the Rat
- Julianne Buescher - Yolanda the Rat (voice)
- Julianne Buescher - Yolanda (voice)
- Julianne Buescher - Yolanda the Rat / Denise (voice)
- Mike Quinn - Additional Muppet Performer (voice)
- Michelan Sisti - Additional Muppet Performer (voice)
- Lauran September - Sabrina
- Mitch Grassi - Pentatonix
- Scott Hoying - Pentatonix
- Avi Kaplan - Pentatonix
- Kirstin Maldonado - Pentatonix
- Kevin Olusola - Pentatonix
- Joy Jacobson - Wife
- Mike Ostroski - Husband
- Marco Rodríguez - Older Latino Man
- Tyler Bunch - Additional Muppet Performer (voice)
- Alice Dinnean - Additional Muppet Performer (voice)
- Alice Dinnean - Alynda (voice)
- Kevin Carlson - Additional Muppet Performer (voice)
- Ian Ziering - Ian Ziering
- Jim Turner - Man
- Petra Sprecher - Aerial Instructor
- Michael Cotter - Stage Manager
- Lara Spencer - Lara Spencer
- Hilty Bowen - Model
- Kamilla Alnes - Model
- Ben Seaward - Extra! Reporter
- Connor Rosen - Child
- Treisa Gary - Patient
- Sean W. Johnson - Additional Muppet Performer (voice)
- James Murray - Additional Muppet Performer (voice)
- Jim Henson
Lea Thompson interpreta a Herself en la serie.
Reese Witherspoon interpreta a Herself en la serie.
Laurence Fishburne interpreta a Himself en la serie.
Riki Lindhome hace el papel de Becky.
Steve Whitmire interpreta a Kermit / Statler / Beaker / Rizzo (voice) en la serie.
Eric Jacobson interpreta a Miss Piggy / Fozzie Bear / Animal (voice) en la serie.
Dave Goelz interpreta a The Great Gonzo / Waldorf / Zoot (voice) en la serie.
Peter Linz hace el papel de Angel Marie / Walter / Happy Yellow Creature (voice).
Capítulo disponible en las siguientes plataformas:
