- Ricardo Montalban - 'Spanish John' Espejo
- Robert Duvall - Bill Andrews
- Sylvia Sidney - Adela Collins
- Mark Lenard - Assistant District Attorney Holloman
- Frank Gorshin - Harry Simms
- Robert Redford - Gary Degan
- Larry Gates - Prof. Robert Hopkins
- John Marley - District Attorney Samartino
- Rudy Bond - Cy Wright
- Martin Landau - Dr. Daniel Orren
- Philip Coolidge - Joe Lundeen
- Edward Binns - District Attorney Wolf
- Michael V. Gazzo - Schultz
- Richard Bright - Phil Macy
- Dustin Hoffman - Buddy
- Gene Wilder - Waiter
- Jack Albertson - Roger Bailey Sr.
- Robert Loggia - Jerry Thomas
- Miriam Colon - Carmella Lopez
- Martin Balsam - District Attorney
- Dean Stockwell - Arnold Foster
- Lois Smith - Esther Terranova
- Michael Higgins - Dr. Fowler
- Melinda Dillon - Jeannie Birch
- Charles Durning - Juror #11
- Gene Hackman - Stanley McGuirk
- Albert Dekker - Mark Vronis
- Val Avery - Strafaci
- William Shatner - Assistant District Attorney Earl Rhodes
- Jerry Orbach - J.P. Loring
- Pat Hingle - Peter Dowling
- Billy Dee Williams - Private Austin George
- Dennis Hopper - Jason Thomas
- Bruce Kirby - Italian Record
- Barnard Hughes - Lester Swann
- Robert Thom
- Reginald Rose
- Bob Markell
- Herbert Brodkin
Ricardo Montalban hace el papel de 'Spanish John' Espejo.
Robert Duvall interpreta a Bill Andrews en la serie.
Sylvia Sidney hace el papel de Adela Collins.
Mark Lenard interpreta a Assistant District Attorney Holloman en la serie.
Frank Gorshin interpreta a Harry Simms en la serie.
Robert Redford interpreta a Gary Degan en la serie.
Larry Gates hace el papel de Prof. Robert Hopkins.
John Marley interpreta a District Attorney Samartino en la serie.
Rudy Bond interpreta a Cy Wright en la serie.
Martin Landau interpreta a Dr. Daniel Orren en la serie.
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