- Zrinka Cvitešić - Sara
- Josef Altin - Pavel
- Samantha Spiro - Detective Taylor
- Richard Cunningham - Danny's Lawyer
- David Hayman - Mr. Turner
- David Hayman - Mr Turner
- Charlotte Rampling - Frances
- Lorraine Ashbourne - Mrs. Turner
- Lorraine Ashbourne - Mrs Turner
- Nicolas Chagrin - Charles
- Harriet Walter - Claire
- Adrian Lester - Professor Marcus Shaw
- Riccardo Scamarcio - Doppelganger
- Tatsujiro Oto - Geisha
- Gintare Beinoraviciute - Clubber (uncredited)
- Neil Alexander Smith - Nightclub Doorman (uncredited)
- Kate Dickie - Editor
- Michaela Coel - Journalist
- Grant Stimpson - Danny's Boss
- Clarke Peters - The American
- Mark Gatiss - Rich
- Steffan Donnelly - Raphael
- Heronimo Sehmi - Club Staff
- James Fox - James
- Henry Goodman - Silversmith
- Sean McKee - Dealer
- Priyanga Burford - Clinician
- Priyanga Burford - Clinician (uncredited)
- Jay Benedict - Phone Voice (voice)
- Lizzy McInnerny - Danny's Mother
- David Meyer - Danny's Father
- Sam Kenyon - HIV Group Chair
- Louis Saint-Juste - Oldest Guy
- Matthew Stagg - Young Alex
- Nicola Grier - Agent in the Attic
- Chris Wilson - CID Officer (uncredited)
- Antonia Campbell-Hughes - Magician
- Jakob Verbruggen
- Tom Rob Smith
- Robert Sterne
- Hilary Salmon
- Polly Hill
- Tim Bevan
- Eric Fellner
- Robert Brazier
- Keefus Ciancia
- Ben Cross
- James Gregory
James Fox interpreta a James en la serie.
Ben Whishaw interpreta a Danny en la serie.
Edward Holcroft interpreta a Alex en la serie.
Jim Broadbent hace el papel de Scottie.
David Hayman interpreta a Mr. Turner en la serie.
Lorraine Ashbourne hace el papel de Mrs. Turner.
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