- Katherine Kelly - DI Karen Renton
- Amy Nuttall - Winnie Peterson
- Sam Spruell - Oliver Graham
- Harry Capehorn - Scottish hotel receptionist
- Donna Banya - Rebecca
- Conrad Peters - David
- Jill Buchanan - English Teacher
- Douglas Bunn - Police Officer
- Andrew Greenough - Taxi driver
- Franc Ashman - Forensic examiner
- Franc Ashman - SARC Nurse
- Simon Manley - Diner
- Beverley Klein - Michaela
- Peter Davison - Denis Walters
- Genevieve Barr - Dr. Hartley
- Tsion Habte - Makeda Kidane
- Vanessa Hehir - Sara
- Shanice Sewell - Nurse
- Dejan Bućin - Man Being Chased
- Fatah Ghedi - Postman
- Rosie Fellner - Beth
- David Avery - Officer Brown
- Adjoa Andoh - Margaret Rust
- Clare Higgins - Felicity Cassidy
- Simon Poland - Chief inspector
- Ty Hurley - Police Inspector
- Mandana Jones - Dr. Rachael Kyle
- Evelyn Duah - Counsellor
- Finn Bennett - Ewen
- Laura Aikman - Charlotte
- Eileen Davies - Sylvia
- Ivana Basic - Mia Lentzovka
- Akbar Kurtha - Birav Suri
- Akbar Kurtha - Birav
- Chu Omambala - Semer
- Shun Yin - Soco
- Cindy Humphrey - TV Reporter
- Michelle Jeram - Detention Officer
- Matthew David McCarthy - Builder
- Paul O'Kelly - Barman
- Joakim Skarli - Man in Bar
- Oliver Maltman - Nick Pillar
- David Kennedy - Reporter Austin
- Tomi Sunmonu - Receptionist
- Stephen Samson - P. C R. Michaels
- Shauna MacDonald - Mary Earlham
- Dawn Steele - Catherine McAulay
- Dermot Crowley - Henry Neilson
- Agni Scott - Dr. Hamood
- Alex Jordan - Joshua
- Carolin Stoltz - Dr. Engers
- Josh Zaré - Dylan
- Clara Onyemere - DC Rochelle Thompson
- Michael Wildman - DI Michael McCoy
- Sian Clifford - Ruby Allen
- Jo Martin - Debbie
- Tim Chipping - DS Nigel Wilson
- Tania Rodrigues - Judge
- Lucy Speed - Counsellor
- Kieran Bew - Ian Davis
- Jill Halfpenny - Jennifer Robertson
- Howard Charles - Carl Peterson
- Jenny Galloway - Hotel Receptionist
- Freya Evans - Nurse
- Jack Colgrave Hirst - Greg Maxwell
Akbar Kurtha interpreta a Birav Suri en la serie.
Joanne Froggatt interpreta a Laura Nielson en la serie.
Ioan Gruffudd interpreta a Andrew Earlham en la serie.
Zoë Tapper interpreta a Katy Sutcliffe en la serie.
Shelley Conn interpreta a DI Vanessa Harmon en la serie.
Danny Webb interpreta a DS Rory Maxwell en la serie.
Richie Campbell interpreta a Liam Sutcliffe en la serie.
Katherine Kelly interpreta a DI Karen Renton en la serie.
Amy Nuttall interpreta a Winnie Peterson en la serie.
Sam Spruell hace el papel de Oliver Graham.
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